Air pollution we breathe: Assessing the air quality and human health impact in a megacity of Southeast Asia.

With 24 million inhabitants and 6.6 million vehicles on the roads, Karachi, Pakistan ranks among the world's most polluted cities due to high levels of fine particulate matter (PM2.5). This study aims to investigate PM2.5 mass, seasonal and temporal variability, chemical characterization, source apportionment, and health risk assessment at two urban sites in Karachi. Samples were analyzed using ion chromatography and dual-wavelength optical transmissometer for various inorganic components (anions, cations, and trace elements) and black carbon (BC). Several PM2.5 pollution episodes were frequently observed, with annual mean concentrations at Kemari (140 ±â€¯179 µg/m3) and Malir (95 ±â€¯40.9 µg/m3) being significantly above the World Health Organization's guidelines of 5 µg/m3. Chemical composition at both sites exhibited seasonal variability, with higher pollution levels in winter and fall and lower concentrations in summer. The annual average BC concentrations were 4.86 ±â€¯5.29 µg/m3 and 4.52 ±â€¯3.68 µg/m3, respectively. A Positive Matrix Factorization (PMF) analysis identified 5 factors, crustal, sea salt, vehicular exhaust, fossil-fuel combustion, and industrial emission. The health risk assessment indicated a higher number of deaths in colder seasons (fall and winter) at the Kemari (328,794 and 287,814) and Malir (228,406 and 165,737) sites and potential non-carcinogenic and carcinogenic risks to children from metals. The non-carcinogenic risk of PM2.5 bound Pb, Fe, Zn, Mn, Cr, Cu and Ni via inhalation exposure were within the acceptable level (<1) for adults. However, potential non-carcinogenic and carcinogenic health risk posed by Pb and Cr through inhalation were observed for children. The findings exhibit critical levels of air pollution that exceed the safe limits in Karachi, posing significant health risks to children and sensitive groups. Our study underscores the urgent need for effective emission control strategies and policy interventions to mitigate these air pollution risks.

Occupational lead exposure health risk assessment and heme biosynthesis: A study on batik artisans in yogyakarta, Indonesia.

This study aims to assess dermal and inhalation lead exposure levels among batik industry workers and evaluate noncarcinogenic and carcinogenic health risks associated with lead exposure. We investigate potential relationships between lead exposure (dermal average daily dose and inhalation exposure concentration) and the workers' blood hemoglobin levels (Hb), as well as their urinary ALA (u-ALA) concentrations. Additionally, we explore any possible associations between Hb and u-ALA levels among the workers and identify various factors influencing lead exposure levels. A total of 30 workers were recruited for the study. Interviews and exposure sampling were conducted to measure dermal and inhaled lead exposure. Sample analysis methods include XRF for exposure samples, spectrophotometry for u-ALA, and HiCN colorimetric for Hb. Carcinogenic and noncarcinogenic risk assessments, correlation analysis, as well as ANOVA for factors analysis, were performed. The average dermal exposure dose and inhalation exposure concentration of lead were 6.53 ± 3.2 ng/kg/day and 0.021 ± 0.015 µg/m3, respectively. Hazard Index (HI) values for all workers were below 1 (average: 0.372 ± 0.155), indicating no expected noncarcinogenic health effects due to lead exposure. The average Excess Lifetime Cancer Risk (ELCR) was (5.18 ± 3.84) × 10-8, significantly below acceptable limits. Correlation analysis revealed a significant negative correlation between Hb and u-ALA (r = -0.519, p = 0.058 for male workers and r = -0.531, p = 0.034 for female workers), supporting their use as lead exposure biomarkers. The factors analysis demonstrated a significant impact of working conditions on inhalation exposure (p = 0.018), with outdoor workers experiencing lower lead inhalation. This research provides crucial insights into potential dangers faced by batik workers due to lead exposure, emphasizing the importance of targeted interventions. The strong correlation between Hb and u-ALA indicates their combined effectiveness in detecting lead exposure, even at low levels. The study underscores the significance of outdoor work as a protective measure against inhaling heavy metals, such as lead, present in the air. The assessment of health risks associated with lead exposure in the batik industry lays the groundwork for informed decision-making and interventions to protect workers' well-being, particularly in informal sectors workplaces where health risks are often overlooked.

Impacts of a lead smelter in East Java, Indonesia: degree of contamination, spatial distribution, ecological risk, and health risk assessment of potentially toxic elements in soils.

This study investigates the characteristics of potentially toxic elements in soils collected from the vicinity of a lead smelter in East Java, Indonesia. The objective is to assess the impact of the lead smelter on the surrounding soil. The study involves chemical composition analysis, spatial distribution mapping, and potential ecological and health risk assessments. Soil samples were collected from the surface area (0-10 cm) and subsurface (15-30 cm) within radii of 1.5 km, 3 km, and 5 km from the lead smelter. The samples were analyzed for As, Cr, Cu, Ni, Pb, and Zn using energy-dispersive X-ray fluorescence. Principal component analysis (PCA) was performed to identify the sources of potentially toxic elements in the soil. The results indicate severe Pb contamination within a 1.5 km radius of the smelter, with an average contamination factor (Cf) value of 22.0, posing a high potential health risk. The contamination factor indicated that the soils were heavily polluted by As and Pb and moderately polluted by Cu, Ni, and Zn. The results of PCA showed that smelter releases are the main source of potentially toxic element contamination in the soil, accounting for 66.2%. The health risk assessment suggested that the children and adults in the study region were exposed to non-carcinogenic risks caused by As and Pb. Oral ingestion was identified as the primary exposure route impacting health risks. The carcinogenic risk from potentially toxic elements in soil was found to exceed the acceptable level for children and adults in the study region. Therefore, it is necessary for the government to take effective measures, including designing regulations and interventions, and improving lead smelter management to mitigate potential contamination and minimize the impact of lead smelter releases on the surrounding environment, especially to protect human health, particularly that of children.

Fine particulate matter and its chemical constituents' levels: A troubling environmental and human health situation in Karachi, Pakistan.

Like many urban centers in developing countries, the effect of air pollution in Karachi is understudied. The goal of this study was to determine the chemical characterization, temporal and seasonal variability, sources, and health impacts of fine particulate matter (PM2.5) in Karachi, Pakistan. Daily samples of PM2.5 were collected using a low-volume air sampler at two different sites (Makro and Karachi University) over the four seasons between October 2009 and August 2010. Samples were analyzed for black carbon (BC), trace metals, and water-soluble ions. Results showed that the annual average concentrations of PM2.5 at Makro and Karachi University were 114 ± 115 and 71.7 ± 56.4 µg m-3, respectively, about 22.8 and 14.3-fold higher than the World Health Organization annual guideline of 5 µg m-3. BC concentrations were 3.39 ± 1.97 and 2.70 ± 2.06 µg m-3, respectively. The concentrations of PM2.5, BC, trace metals, and ions at the two sites showed clear seasonal trends, with higher concentrations in winter and lower concentrations in summer. The trace metals and ionic species with the highest concentrations were Pb, S, Zn, Ca, Si, Cl, Fe, and SO42-. The air quality index in the fall and winter at both sites was about 68 %, which is "unhealthy" for the general population. Positive Matrix Factorization revealed the overall contribution to PM2.5 at the Makro site came from three major sources - industrial emissions (13.3 %), vehicular emissions (59.1 %), and oil combustion (23.3 %). The estimates of expected number of deaths due to short-term exposure to PM2.5 were high in the fall and winter at both sites, with an annual mean estimate of 3592 expected number of deaths at the Makro site. Attention should be paid to the reduction of inorganic pollutants from industrial facilities, vehicular traffic, and fossil fuel combustion, due to their extremely high contribution to PM2.5 mass and health risks.

The air quality of Palangka Raya, Central Kalimantan, Indonesia: The impacts of forest fires on visibility.

Airborne particles in urban Palangka Raya, Kalimantan from Oct 2011 until Oct 2020 have been collected and analyzed for PM2.5, PM10, and Black Carbon (BC) concentrations. Palangka Raya is a city that serves the capital of the Central Kalimantan province on the island of Borneo. Kalimantan is affected by peat fires that occur periodically. There were identified increases in PM2.5 and PM10 concentrations during El Niño periods. During the forest fire episode in September - October 2015, PM2.5 and PM10 concentrations increased significantly, to nearly 400 µg/m3 and 800 µg/m3, respectively, and visibility in the city was reduced to < 0.2 miles. The highest BC concentrations were observed during this massive forest fires episode. The regression analyses for PM2.5, PM10 and visibility in Palangka Raya during the period of 2011-2020, showed a non-linear correlation with reduction in visibility due to increased PM2.5 and PM10. There was no correlation for BC with visibility. Air quality in Palangka Raya was at a relatively good level with concentrations below the national ambient air quality standard when there were no forest fires event. Emissions from forest fires caused a substantial reduction in air quality reaching concentrations well above ambient air quality standards and are likely to have caused adverse health effects on the people living in the area.Implications: Indonesia has repeatedly experienced forest fires, especially on Kalimantan and Sumatera Islands, which burned large areas of peatland. The forest fires leading to increasing PM concentrations especially in the PM2.5 size range which influence visibility. The seasonal variations of BC in Palangka Raya and the relationships of fine particulates with visibility were assessed. The results of regression analyses for PM2.5 and PM10 to visibility during the period of 2011-2020 showed non-linear relationships. An increasing of PM2.5 and PM10 concentrations during El Nino periods were detected well above the ambient air quality standard. To ensure effective and continued handling and prevention of forest and peatland fires, the government set up a special task force and review on several rules, including laws and government regulations as well as governor regulations that permit the burning of forest and peatland areas. These results are expected to be used to formulate more effective mitigations in reducing forest fires events in Indonesia.

Increase of Cardiometabolic Biomarkers Among Vehicle Inspectors Exposed to PM0.25 and Compositions.

BACKGROUND: Exposure to particulate matter (PM) emitted from vehicle exhaust might disrupt systemic function and elevate the risk of cardiovascular disease. In this study, we examined the changes of cardiometabolic biomarkers among vehicle inspectors exposed daily to PM0.25 and components. METHODS: This cross-sectional study was conducted at two vehicle inspection centers, Pulogadung and Ujung Menteng, located in East Jakarta, Indonesia. The exposed respondents were 43 workers from vehicle inspection centers, and the unexposed group consisted of 22 staff officers working in the same locations. Vehicle exhaust particulate matter was measured for eight hours using a Leland Legacy personal pump attached to a Sioutas Cascade Impactor. The used filters were 25 and 37-mm quartz filters. The particulate matter concentration was analyzed using a gravimetric method, whereas trace elements were analyzed using energy dispersive X-ray fluorescence. An EEL Smoke Stain Reflectometer analyzed black carbon. RESULTS: The personal exposure concentrations of PM0.25 were 10.4-fold higher than those in unexposed groups. Calcium and sulfur were the major components in the obtained dust, and their levels were 3.3- and 7.2-fold higher, respectively, in the exposed group. Based on an independent-samples t-test, high-density lipoprotein, triglyceride, HbA1c, total immunoglobulin E, high-sensitivity C-reactive protein, tumor necrosis factor-alpha, and nitric oxide levels were significantly different between the groups. CONCLUSIONS: In summary, it was suggested that PM0.25 exposure from vehicle exhaust might affect cardiometabolic biomarkers change.

Determinations of Minerals Composition of Rices in Java Island, Indonesia.

Rice (Oryza sativa L.) is one of the staple foods widely consumed by Indonesian people. They usually have rice as the biggest portion on their diet, therefore rice becomes the main source of nutrients of Indonesian people mainly for those whom live in Java Islands. Although rice is known to contain various minerals, but the minerals level are varied based on differences in geographic region associated with soil quality. Hence, quantity and quality of minerals content of rice from different regions of the world are particularly important to be characterized. The present aim of the study was to assess the composition of mineral of rice from different geographical regions in Java Islands, Indonesia using nuclear analytical techniques i.e. Neutron Activation Analysis method... Quality control of data analysis was assessed using SRM NIST Rice Flour 1568a and gave good results with accuracy (% bias) ≤5% and precision (%CV) less than 10%. The essential elements contents such as Fe, Zn, and Se were quantified and found in the range of 2.8-60.9, 2.48-28.8, and 0.01-2.17 mg/kg respectively, while for the toxic elements, Cr and Co in rice are also quantified and found in the range of 0.03-1.24 and 0.003-0.59 mg/kg, respectivelyThe elemental concentrations in rices from Java Island followed the order Zn>Fe>Se>Cr>Co. It also found that rices from East Java Province have higher concentrations of Fe and Se, while the highest mean of Zn concentration was found in the rices from Jakarta province. The daily intake of those elements in rices give significant contribution to their RDA values. These results of mineral contents in rice hopefully can be used as one of references for estimating daily nutritional intake status of especially Javanese people.

Characterization of Micronutrients in Tofu from Several Cities in Java Island Indonesia.

Tofu is a traditional food such as curd made from soymilk with additional coagulants which is widely consumed by people in Indonesia and Asian countries. Tofu is one of the important sources of micronutrients, such as cobalt (Co), chromium (Cr), iron (Fe), selenium (Se) and zinc (Zn). Therefore, the content of various elements both toxic and essential need to be studied to ensure the food safety and estimating their contribution to daily intake. METHODS: In this research, the determination of micronutrient content in tofu was carried out in the samples collected from traditional market in Jakarta, Yogyakarta, West, Central and East Java Provinces during the period 2010-2014. Determination of elemental concentration was carried out using neutron activation analysis (NAA) methods. RESULTS: Analysis result showed that the elemental concentrations of Co, Cr, Fe, Se and Zn in tofu were in the range of 0.001-0.27; ≤0.001-0.35; ≤0.050-62.90; ≤0.0046-5.34 and 0.02-21.19 mg/kg respectively. The daily intake value of tofu is calculated by estimating their contribution based on the concentration and consumption data. The average daily intake of Co, Cr, Fe, Se and Zn contributes to 1.33-11.95; 2.10-2.93; 2.66-5.99, 13.1 and 1.95-2.69% of RDA values for adult women and men. CONCLUSIONS: The analysis shows that there are variations in the concentration of micronutrients contained in tofu from the five provinces. Tofu has contributed RDA of Co, Cr, Fe, Se, and Zn in almost all regions observed, tofu consumption contributed only a low fraction of RDA value for an adult.

Atmospheric black carbon in PM2.5 in Indonesian cities.

UNLABELLED: Samples of airborne particulate matter were collected at several cities in Indonesia: Bandung, Jakarta, Palangka Raya, Serpong, and Yogyakarta, from January through December 2011. The samples were collected once a week using a Gent stacked filter unit sampler in two size fractions of 2.5 microm (fine, PM2.5) and 2.5 to 10 microm (coarse, PM2.5-10). Black carbon was measured using an EEL smoke stain reflectometer The average of PM2.5 during the sampling period for Bandung, Jakarta, Palangka Raya, Serpong, and Yogyakarta sites was 18.35, 16.50, 7.74, 16.68, and 8.78 microg/m3, respectively. The average of BC for Bandung, Jakarta, Palangka Raya, Serpong and Yogyakarta was 3.05, 3.37, 3.19, 2.51, and 2.20 microg/m3, respectively. The ratio of the 24-hr BC concentration compared to the PM2.5 concentrations showed that BC comprises about 17-45% of the fine particulate matter collected at all sites. The average percentage of BC in PM2.5 concentrations in Bandung, Jakarta, Palangka Raya, Serpong, and Yogyakarta was 18, 22, 45, 17, and 26%, respectively. Bandung and Jakarta compared with Yogyakarta showed higher concentrations of PM2.5 and BC, which indicated pollution occurring in Bandung and Jakarta is more intense than in Yogyakarta, while the maximum of BC concentration and the percentage of BC in PM2.5 in Palangka Raya were 6.04 microg/m3 and 75%, respectively This higher BC concentration than the other cities was due to the forest fires that occurred frequently during the sampling period. The contributions of BC source in these cities were also analyzed to ascertain the local sources of BC. IMPLICATIONS: BC in PM2.5 was monitored over the period of January-December 2011 in several big cities in Indonesia to provide quantitative information on BC concentrations and contributions to PM2.5 and for comparison among these cities and with other Asian countries. This study supports the national air quality monitoring projects. The results of black carbon concentrations in these areas indicate source contributions from local sources such as forest fire, biomass burning, and vehicle emissions.

Urban air quality in the Asian region.

Over the past decade, member states of the Regional Co-operation Agreement (RCA), an intergovernmental agreement for the East Asia and Pacific region under the auspices of the IAEA with the assistance of international organizations and financial institutions such as the World Bank and the Asian Development Bank, have started to set in place policies and legislation for air pollution abatement. To support planning and evaluate the effectiveness of control programs, data are needed that characterizes urban air quality. The focus of this measurement program describe in this report is on size segregated particulate air pollution. Such airborne particulate matter can have a significant impact on human health and urban visibility. These data provide the input to receptor models that may permit the mitigation of these impacts by identification and quantitative apportionment of the particle sources. The aim of this report is to provide an overview of the measurements of concentrations and composition of particulate air pollution in two size fractions across the participating countries. For many of the large cities in this region, the measured particulate matter concentrations are greater than air quality standards or guidelines that have been adopted in developed countries.

Sources identification of the atmospheric aerosol at urban and suburban sites in Indonesia by positive matrix factorization.

Samples of fine and coarse fractions of airborne particulate matter were collected in Indonesia (west central Java) at an urban site in Bandung and in suburban Lembang from January 2002 to December 2004. The samples were collected using a Gent stacked filter sampler in two size fractions of <2.5 microm (fine) and 2.5 to 10 microm (coarse). The samples were analyzed for elemental concentrations by instrumental neutron activation analysis (INAA) and proton-induced X-ray emission (PIXE). Black carbon was determined using an EEL Smoke Stain Reflectometer. The data sets were then analyzed using positive matrix factorization to identify the possible sources of fine and coarse atmospheric aerosols in both areas. The best solutions were found to be seven factors and five factors for elemental compositions of fine and coarse particulate matter in the urban area of Bandung and six factors and five factors for elemental compositions of fine and coarse particulate matter in the suburban area of Lembang, respectively. The sources are soil dust, motor vehicles, biomass burning, sea salt, and road dust. The PMF results showed that more than 50% of the PM2.5-10 mass at both sites comes from soil dust and road dust. The biomass burning factor contributes about 40% of the PM2.5 mass in case of suburban Lembang and about 20% in urban Bandung.