RESUMO
The development of animal models for research has been very diffused. Osteoarthritis is a joint degenerative pathology that induces cartilage erosion, chondrocyte proliferation and osteophyte formation. The aim of this paper is to present a technical procedure to perform the injection of monosodium iodine acetate in the temporomandibular joints of rats to generate osteoarthritis and to contribute to future research analysis related to pathology progression and proper treatment performance. The use of rat models may be a complex process because of their size, but they can be compared to the human temporomandibular joint due to the similar characteristics and the possibility of performing diagnosis and treatment protocols in order to detect this pathology.
Assuntos
Modelos Animais de Doenças , Injeções Intra-Articulares/métodos , Compostos de Iodo/toxicidade , Osteoartrite/induzido quimicamente , Articulação Temporomandibular/anatomia & histologia , Animais , Ratos , Ratos Sprague-DawleyRESUMO
A high-resolution X-ray diffraction beamline at the Brazilian Synchrotron Light Laboratory (LNLS) has been commissioned for the study of crystalline magnetic materials. The beamline optics is based on a Rh-coated vertical-focusing X-ray mirror and a sagittal-focusing double-crystal monochromator. The primary instrument is a six-circle diffractometer equipped with energy and polarization analysers and a closed-cycle He cryostat. The beamline source is a bending magnet of the 1.37 GeV storage ring of the LNLS, delivering approximately 4 x 10(10) photons s(-1) at 8 keV at the sample position. Resonant and non-resonant scattering are the main techniques used to study charge, orbital and magnetic structures. Examples of magnetic scattering in Ho and NiO single crystals, as well as orbital ordering in manganites thin films, are presented.
Assuntos
Hólmio/química , Magnetismo , Níquel/química , Eletricidade Estática , Síncrotrons/instrumentação , Difração de Raios X/instrumentação , Difração de Raios X/métodos , Brasil , Desenho de Equipamento , Análise de Falha de Equipamento , Laboratórios , Reprodutibilidade dos Testes , Espalhamento de Radiação , Sensibilidade e Especificidade , TemperaturaRESUMO
La uncinariasis es una parasitosis causada por dos especies de nematodes, el Necator Americano y el Anquilostoma Duodenale, con una clinica que varia con la edad, alimentacion, raza, embarazo, intensidad de la infeccion y especie de uncinaria. Por no existir informacion respecto a la prevalencia de ambas especies en la patologia regional, es que se considero una prioridad la realizacion del presente trabajo. Las muestras procedentes de la provincia Chapare y Cercado fueron cultivadas de acuerdo a la tecnica de Harada-Mori para identificacion de larvas 3. Los resultados obtenidos de 50 muestras procesadas dieron cuenta de la presencia de solo larvas de A. Duodenale en el 100% de ellas. Teniendo en cuenta que la presencia de A. Duodenale confiere a un foco endemico mayor gravedad, nuestros resultados son una alerta a las autoridades de salud que tiene bajo su responsabilidad el control la profilaxis y educacion en nuestro medio
