[Congenital anomalies of the inferior vena cava: diagnosis and medical treatment].

Analyzed herein are the findings obtained following an examination and medical treatment of five 17-to-39-year-old male patients (average age 25.0+/-1.83 years) presenting with congenital abnormalities of the inferior vena cava. The diagnosis was made and the level of aplasia was determined based on the findings of a comprehensive instrumental examination (computed and magnetic resonance tomography of the abdominal cavity, duplex scanning of the veins of the lower extremities, of the pelvis and the retroperitoneal space, as well as on the data of pelvic phlebography, and retrograde cavography). In three of the five patients, the disease appeared to have for the first time manifested itself by a clinical picture of peripheral thrombosis (oedema of the crus and femur), and in the remaining two by an elevated body temperature and shivering, followed by oedema of the both lower limbs. Two patients were found to have aplasia of the infrarenal segment of the inferior vena cava, two subjects had aplasia of the infra-, renal and partially suprarenal portions of the vessel, and one patient suffered from aplasia of virtually the whole vena cava, excepting a small part of the suprahepatic portion, toward which converged the hepatic veins and the superior polar renal vein. With the purpose of early diagnosis of congenital abnormalities of the inferior vena cava, the protocol of examination of patients with venous diseases should include ultrasonographic mapping of the supra-, renal and infrarenal portions of the vena cava, and if agenesis is revealed, the use of computed or magnetic resonance tomography, retrograde cavography is strongly recommended. When the diagnosis of IVC aplasia is confirmed, primary medical treatment should consist in prescribing venotonic agents, elastic compression and in cases of deep veins thrombosis -anticoagulant therapy.

[Deep vein thrombosis as the manifestation of congenital anomaly of inferior vena cava].

Results of examination of 5 male patients aged 20 to 43 years with congenital anomaly of inferior vena cava are analyzed. Complex special examination (CT, MRI, duplex scanning, pelvic phlebography, retrograde cavagraphy) was used for correct diagnosis. Primary treatment of agenesis of inferior vena cava should consist of elastic compression and phlebotonics; in cases of deep vein thrombosis anticoagulants must be used.

[An epidemiological study of herpetic viral infections in the Republic of Byelarus]. / Izuchenie épidemiologii gerpeticheskikh virusnykh infektsii v Respublike Belarus'.

Studies on the epidemiology of infections caused by Herpes simplex virus, cytomegalovirus and Epstein-Barr virus in different age groups of the population of the Republic of Belarus, carried out over the period of many years, are summarized. The frequency of clinical manifestations of different forms of herpetic viral pathology in newborns, children and adults in different regions of the republic was studied. More frequent cases of the most severe clinical forms of herpetic viral infections (encephalitides, generalized infection) were noted in persons having immunodeficient states of different etiology, as well as among the population residing on the territory with unfavorable radiation conditions as a consequence of the catastrophe in the Chernobyl nuclear electric power station. For further study of the specific features of the epidemiology of herpetic obligatory registration of all cases of herpetic viral infections, starting from January 1, 1996, was introduced.

[The antioxidant status of children with congenital cleft lip and (or) palate]. / Antioksidantnyi status detei s vrozhdennymi rasshchelinami guby i (ili) neba.

Lipid peroxidation (LPO) parameters, Schiff's bases and diene conjugates (DC), as well as endogenous antioxidant system parameters, blood serum alpha-tocopherol were examined in 22 children with cleft lips and/or palates and their parents. DC LPO processes were found intensified in both children and their parents. Various DC levels were detected in probands: normal in 4 and significantly elevated (p less than 0.001) in 18 children. A group of children with intensified LPO processes and a reduced level of endogenous antioxidant activity was distinguished, that appears to be a risk group in respect of postoperative complications and therefore is in need of adequate preoperative antioxidant correcting therapy.

[The prospects for the antenatal preventive therapy of congenital developmental defects]. / Perspektivy antenatal'noi profilakticheskoi terapii vrozhdennykh porokov razvitiia.

Prenatal diagnosis of congenital diseases using specialized and expensive enough methods and abortion in case of defect revealing are regarded today as the main approach to their control. The paper is concerned with an alternative approach lying in the preconceptional and antenatal therapy in order to arrest the occurrence of developmental abnormalities. The data on the role of vitamins in the origin of congenital defects of the neural tube as well as on possibilities of the antenatal therapy by a complex of vitamin drugs are provided.