RESUMO
Sarcomas constitute approximately 1% of adult cancers and 8%-10% of paediatric cancers. Undifferentiated pleomorphic sarcoma (UPS) is a type of soft-tissue sarcoma (STS) characterised by dedifferentiated cancer cells. The most common sites of metastasis for UPS include the lungs, liver, bones and regional lymph nodes. Brain metastasis is rare, affecting only 1%-8% of STS patients. This report presents a unique case of a woman in her 80s with a TET2-mutant UPS metastatic to the lung and brain.
Assuntos
Neoplasias Encefálicas , Proteínas de Ligação a DNA , Dioxigenases , Neoplasias Pulmonares , Proteínas Proto-Oncogênicas , Sarcoma , Humanos , Feminino , Neoplasias Pulmonares/genética , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/secundário , Neoplasias Encefálicas/secundário , Neoplasias Encefálicas/genética , Neoplasias Encefálicas/diagnóstico por imagem , Sarcoma/genética , Sarcoma/secundário , Sarcoma/patologia , Proteínas Proto-Oncogênicas/genética , Proteínas de Ligação a DNA/genética , Idoso de 80 Anos ou mais , Mutação , Evolução FatalRESUMO
Few descriptions of using the femoral vein as an arterial replacement exist in the pediatric surgical literature. A 3-year-old child sustained a gunshot wound to the right subclavian artery, which resulted in ischemia to the upper extremity. The left femoral vein was harvested and used to reconstruct the subclavian artery. This report highlights a rare case of subclavian artery reconstruction using a femoral vein conduit in a young child after a penetrating injury.