A randomized clinical trial on zirconia versus titanium implants in maxillary single tooth replacement.

OBJECTIVES: This RCT aimed to compare zirconia and titanium dental implants in the maxillary premolar region. The comparison was based on marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs) 1 year after prosthetic loading. MATERIALS AND METHODS: Fifty patients were randomly assigned to receive either a zirconia (ZrO2, n = 25) implant or a titanium (Ti, n = 25) bone-level implant. Implants were provided with a lithium disilicate crown 3 months after placement. Follow-up was at 1 month and after 1 year. The primary outcome pertained to changes in MBL. Reported secondary outcomes consisted of implant survival, peri-implant tissue health, aesthetics, and PROMs. RESULTS: Mean MBL change after 1 year was 0.01 mm (SD = 0.45; min = 0.72, max = 0.86) for ZrO2 and -0.09 mm (SD = 0.34; min = 0.53, max = -1.06) for Ti (p = .439). Scores for the other clinical outcome parameters and PROMs were generally favorable, with no significant differences. However, significant differences were found for the aesthetic outcomes regarding two criteria: (a) level of facial mucosa (p = .022), in favor of Ti, and (b) root convexity/soft tissue color and texture (p = .005) in favor of ZrO2. CONCLUSION AND CLINICAL IMPLICATIONS: The ZrO2 and Ti implant types used in this study, replacing a single missing maxillary premolar, show a comparable outcome in terms of MBL change after 1 year. Clinical and aesthetic parameters, as well as PROMs, are favorable and similar between both implant types after 1 year of prosthetic loading. These short-term study results suggest that both are suitable for clinical use.

[Ceramic implants: the state of art]. / Keramische implantaten: de stand van zaken.

A multitude of biomaterials have been used for the production of implants through the years. Titanium or titanium alloy have been regarded as the 'gold standard' for years. However, potential risks and disadvantages regarding biocompatibility and aesthetics have also been reported for the use of titanium in dental implantology. As such, there is need for an alternative material. Zirconia may be regarded as a possible alternative. It is a ceramic with high fracture toughness and other positive qualities, such as beings metal-free, biocompatible, and white, which is aesthetically desirable. Short-term study results of contemporary zirconia implants are promising and comparable to titanium implants. Nevertheless, the material is relatively brittle and susceptible to surface defects. However, no long-term clinical results exists and possible complications are unknown. Long-term clinical research is needed before zirconia implants routine use may be endorsed.

Dimensional changes of CAD/CAM polymer crowns after water aging - An in vitro experiment.

Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) polymers can potentially replace traditional materials used for manufacturing indirect restorations. In 2012, Lava Ultimate (LU) was introduced as a highly suitable material for implant-supported single crowns. Three years after its introduction, the manufacturer issued a change in indication for the material, implying that they no longer considered the material to be suitable for crown indications due to debonding issues. A clinical trial with implant-borne Lava Ultimate crowns bonded to zirconia abutments revealed that 80 percent of the LU crowns showed debonding from the abutment within one year, whereas no debonding occurred when an alternative full-ceramic restoration material was used. These results suggest that the material itself had been the cause of the debonding. However, the exact reason for the debonding remained unclear. Water uptake in resin methacrylates like LU is known to cause dimensional changes resulting in mechanical stress on the RelyX Ultimate (RU) cement. The purpose of this study is to quantify the dimensional changes in LU caused by water uptake and relate these dimensional changes to the failure of the RU cement. Twenty-five identical LU-crowns were divided into three groups. 10 LU-crowns with abutment and 10 crowns without abutments were stored in water for 23 days and were only removed for measurement. Five crowns served as a control to calibrate the measurements. The internal diameter was measured eight times with a TS 460 Heidenhain touch probe. For visualization purposes, one crown was also 3D scanned before and after water treatment. The results showed that after 23 days in water the mean increase in diameter for the groups with and without abutment was 36.6 µm (SD = 35,1) and 36.7 µm (SD = 26,5) respectively. Mixed effects modelling indicated no significant between-group differences at any time point. Exposure of LU to water results in dimensional changes causing mechanical stress on the crown-abutment complex. It can be estimated that RU cement fails after an expansion of more than 4 µm. Within the limitations of this in vitro study, it can be concluded that the dimensional changes induced by water uptake can cause debonding issues. As more CAD/CAM polymers for restorative purposes are expected to be developed, the results of this study should stimulate manufacturers to quantify their products' dimensional changes in a wet environment before market release.

Influence of Deep Margin Elevation and preparation design on the fracture strength of indirectly restored molars.

The objectives of this in-vitro study were to investigate the influence of Deep Margin Elevation (DME) and the preparation design (cusp coverage) on the fracture strength and repairability of CAD/CAM manufactured lithium disilicate (LS2) restorations on molars. Sound extracted human molars (n = 60) were randomly divided into 4 groups (n = 15) (inlay without DME (InoD); inlay with DME (IWD); onlay without DME (OnoD); onlay with DME (OnWD)). All samples were aged (1.2 × 106 cycles of 50N, 8000 cycles of 5-55 °C) followed by oblique static loading until fracture. Fracture strength was measured in Newton and the fracture analysis was performed using a (scanning electron) microscope. Data was statistically analyzed using two-way ANOVA and contingency tables. DME did not affect the fracture strength of LS2 restorations to a statistically significant level (p = .15). Onlays were stronger compared to inlays (p = .00). DME and preparation design did not interact (p = .97). However, onlays with DME were significantly stronger than inlays without DME (p = .00). More repairable fractures were observed among inlays (p = .00). Catastrophic, crown-root fractures were more prevalent in onlays (p = .00). DME did not influence repairability of fractures or fracture types to a statistically significant level (p > .05). Within the limitations of this in-vitro study, DME did not statistical significantly affect the fracture strength, nor the fracture type or repairability of LS2 restorations in molars. Cusp coverage did increase the fracture strength. However, oblique forces necessary to fracture both inlays and onlays, either with or without DME, by far exceeded the bite forces that can be expected under physiological clinical conditions. Hence, both inlays and onlays are likely to be fracture resistant during clinical service.

[Fracture strength of various types of direct and indirect restorations in the functional repair of endodontically treated molars]. / Breuksterkte van verschillende types directe en indirecte restauraties bij het functioneel herstel van endodontisch behandelde molaren.

The fracture strength of endodontically treated molars restored by means of various types of direct and indirect materials was studied in vitro. 105 sound molars were endodontically treated and randomly assigned to 1 control group (endodontic access cavity only) and 6 experimental groups (n = 15) with restorations of the following materials: glass fibre reinforced composite (GFRC); microhybrid composite (C); microhybrid composite restoration with glass fiber post (CP); full-contour lithium disilicate crown (LDS); full-contour lithium disilicate crown with glass fiber post (P-LDS); and an endocrown (EC). Specimens were thermo-mechanically aged and axially loaded until failure. Data were analysed using ANOVA and Tukey's post hoc test (α = 0.05). Fracture strength was significantly affected by the type of restoration (p = 0.000). LDS had significantly higher fracture strength than the control group and GFRC, C and CP groups. Groups EC, LDS and P-LDS were not statistically different from each other in fracture strength. This was also the case with EC, P-LDS and all composite groups. The glass fibre strength of composite restoration resulted in significantly fewer fatal fractures.

Fracture Strength of Various Types of Large Direct Composite and Indirect Glass Ceramic Restorations.

INTRODUCTION: The objective of this study was to investigate the mechanical behavior of severely compromised endodontically treated molars restored by means of various types of composite buildups, full-contour lithium disilicate crowns (with or without post) or a lithium disilicate endocrown. METHODS AND MATERIALS: One hundred five sound molars were endodontically treated and randomly assigned to 1 control group (endodontic access cavity only) and 6 experimental groups (n=15): glass fiber reinforced composite (GFRC group), direct microhybrid composite (C group), direct microhybrid composite restoration with glass fiber post (CP group), composite buildup and full-contour lithium disilicate crown (LDS group), additional glass fiber post (P-LDS group), and endocrown (EC group). Molar crowns in the treatment groups were removed 1 mm above the cementoenamel junction and restored. All specimens were thermomechanically aged (1.2×106 cycles at 1.7 Hz/50N, 8000 cycles 5°C to 55°C) and axially loaded until failure. Data were analyzed using analysis of variance and Tukey post hoc test (α=0.05). RESULTS: Fracture strength was significantly affected by the type of restoration (p=0.000; statistically similar groups identified with superscript letters): LDSB (3217±1052 N), P-LDSAB (2697±665 N), ECAB (2425±993 N), CA (2192±752), controlA (1890±774 N), CPA (1830±590 N), and GFRCA (1823±911 N). Group GFRC obtained significantly more repairable fractures than the other groups. CONCLUSIONS: Significant differences in fracture strength were obtained between LDS, the composite restorations, and control group. Direct composite restorations showed similar fracture strength as P-LDS and EC. Incorporating a glass fiber reinforced composite resulted in significantly more repairable failures.

[A PhD completed. Innovations in restorative dentistry: necessary or superfluous?] / Serie: Hora est. Innovaties in de restauratieve tandheelkunde: nodig of overbodig?

Restorative dentists are faced with a dilemma: they needs to be aware of the most recent developments in order to be able to offer state-of-the-art care but they also have to be able to identify which of the many innovations are superfluous. In this doctoral dissertation the focus was on the role of digital production and procedures in restorative dentistry, and in oral implantology in particular. The variety of studies performed revealed that patients prefer to have impressions taken digitally rather than with dental impression putty and that digital impressions can be taken more quickly. Modern restorative materials are often made of ceramics, such as the white and aesthetically appealing zirconium dioxide (3Y-TZP). It was revealed that zirconia when used as abutment material for implant-born restorations showed no signs of degradation after 1 year of clinical use and was more or less as strong as it had been in the beginning. Milled composite resin crowns, however, that were cemented to them did not adhere well to the ceramic.

On the bulk degradation of yttria-stabilized nanocrystalline zirconia dental implant abutments: an electron backscatter diffraction study.

Degradation of yttria-stabilized zirconia dental implants abutments due to the tetragonal to monoclinic phase transformation was studied in detail by microstructural characterization using Electron Back Scatter Diffraction (EBSD). The amount and distribution of the monoclinic phase, the grain-size distribution and crystallographic orientations between tetragonal and monoclinic crystals in 3 mol.% yttria-stabilized polycrystalline zirconia (3Y-TZP) were determined in two different types of nano-crystalline dental abutments, even for grains smaller than 400 nm. An important and novel conclusion is that no substantial bulk degradation of 3Y-TZP dental implant abutments was detected after 1 year of clinical use.