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Perfusion ; 26(6): 519-23, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21844112

RESUMO

INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery.


Assuntos
Ponte Cardiopulmonar/efeitos adversos , Embolia Gordurosa/diagnóstico , Embolia Gordurosa/etiologia , Reação Transfusional , Ultrassonografia Doppler Transcraniana/métodos , Idoso , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Feminino , Humanos , Masculino , Mediastino/irrigação sanguínea , Mediastino/cirurgia , Pessoa de Meia-Idade , Tamanho da Partícula , Projetos Piloto
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