Association of SARS-CoV-2 Genomic Load with COVID-19 Patient Outcomes

RationaleThe Infectious Diseases Society of America has identified the use of SARS-CoV-2 genomic load for prognostication purposes as a key research question. ObjectivesWe explored the SARS-CoV-2 genomic load as a risk factor for adverse patient outcomes. MethodsA retrospective cohort study among adult patients admitted to the hospital between March 31st to April 10th, 2020 with COVID-19 pneumonia was conducted. We segregated patients into 3 genomic load groups: low (Cycle threshold (Ct) [≥]35), intermediate (25