RESUMO
Assessment of quality of life in patients with different degrees of chronic kidney disease is an important issue because of its impact on clinical decisions and financial resource management in the health-care system. The aim of this study was to assess whether a generic instrument like the SF-36 questionnaire is able to discriminate three different populations of patients with different degrees of renal disease (pre-ESRD, ESRD, TxR). Five hundred sixty-three patients from 12 Italian nephrology units completed the SF-36 scales by themselves. The results from these samples were compared with those from the general population. Univariate analysis and multivariate regression were used. The generic SF-36 questionnaire proved to be a powerful instrument to discriminate populations with different degrees of chronic renal failure. The quality of life of patients on dialysis is significantly worse than that of the normal population and other patients with less severe renal function impairment.
Assuntos
Nefropatias , Qualidade de Vida , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Feminino , Humanos , Nefropatias/diagnóstico , Nefropatias/terapia , Falência Renal Crônica/diagnóstico , Falência Renal Crônica/terapia , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Adulto JovemRESUMO
Since there have been a few reports of pediatric HIV-2 infection. We therefore investigated the perinatal transmission of HIV-2 in 147 malnourished and 164 well-nourished children attending a health center in the northern part of Guinea Bissau. Specific HIV-2 antibodies were detected in 17 mothers and in 2 malnourished children, one of them with pediatric AIDS. This study demonstrates that mother to child transmission of HIV-2 infection occurs in Guinea Bissau and suggests that there is an increased likelihood of detecting HIV-2 infection in malnourished children. The high seroprevalence of HIV-2 in a rural population without known risk factors may represent a hidden threat to mother/child health.
PIP: The authors tested blood samples of 147 malnourished children, 164 well-nourished children, and their 205 mothers with the goal of exploring the extent to which HIV-1 and HIV-2 were being transmitted perinatally in Guinea-Bissau. The children were attending a health center in the northern part of Guinea-Bissau and had been breast fed from birth to 20 months of age or longer. Analysis found antibodies to HIV-2 in 17 mothers and 2 malnourished children, one with pediatric AIDS. These findings demonstrate the occurrence of mother-to-child transmission of HIV-2 in the country and suggest a possible increased likelihood of detecting HIV-2 infection in malnourished children. The high seroprevalence of HIV-2 infection in a rural population without known risk factors may represent a hidden threat to the health of mothers and children.
