Theoretical and practical aspects of receptor hormone assay in breast cancer.

The Authors have discussed the importance of ER/PR assay in breast cancer care. 162 patients were studied. The dextran-coated charcoal technique was used as the standard most readily available. The Authors point out the importance of specimen handling as is shown by time-decay studies, and the differences in ER/PR level at the time of the biopsy and mastectomy cut-section, and its eventual influence to better understanding assay results. The establishment of a center of control between different labs would also help in the development of more exact regimens for cancer care.