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1.
Musculoskelet Surg ; 104(3): 321-328, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31583519

RESUMO

PURPOSE: The treatment of olecranon fracture-dislocations (OFDs) remains challenging. OFDs are often misdiagnosed as Monteggia lesions, and the real frequency is actually higher. However, studies on OFDs are limited. This study aimed to report on the surgical management of OFDs and to highlight the importance of three-dimensional computed tomography (3D CT) evaluation in the treatment of OFDs. MATERIALS AND METHODS: The study participants included 18 patients (11 men, 7 women, mean age 44 years (range 24-78) with OFDs. Each patient's medical records, radiographs, and 3D CT scans were reviewed for demographics, injury details, operative findings, and information about radiological and functional outcomes. The patients were divided into 2 groups according to the direction of the dislocation: the posterior dislocation group (group 1, 7 patients) and anterior dislocation group (group 2, 11 patients). The clinical evaluation was performed according to Broberg-Morrey and the American Shoulder and Elbow Surgeons-Elbow (ASES-E) scoring systems. RESULTS: The mean follow-up period was 39 months (range 25-62 months). The Broberg-Morrey results were excellent in 4, good in 9, fair in 3, and poor in 2 patients. The mean ASES-E score was 84.83 (range 48-100) points. There were signs of ulna-humeral arthrosis in 5 elbows. Arthrosis was graded as grade 1, grade 2, and grade 3 in 3, 1, and 1 elbows, respectively. Partial sensory recovery was observed in one patient with postoperative ulnar neuropathy at the last follow-up visit. CONCLUSIONS: OFDs are complex injuries of the proximal ulna and may involve the radial head, coronoid process, and lateral collateral ligament. The effective treatment of OFDs begins with the proper identification of the injury with 3D CT. A secure fixation including the coronoid process is mandatory for the elbow joint stability. Insufficient restoration of the trochlear notch may lead to problems with loss of motion and arthrosis. Although an application of a pre-contoured locking anatomical olecranon plate can simplify the fixation procedure in most cases, the surgeons' equipment should also include radial head implant, coronoid plates, headless screws, small cannulated screw system, suture anchors, fluoroscopy, and articulated external fixator.


Assuntos
Fratura-Luxação/cirurgia , Imageamento Tridimensional/métodos , Olécrano/lesões , Tomografia Computadorizada por Raios X/métodos , Fraturas da Ulna/cirurgia , Adulto , Idoso , Feminino , Seguimentos , Fratura-Luxação/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Olécrano/diagnóstico por imagem , Osteoartrite/diagnóstico por imagem , Fraturas do Rádio/classificação , Estudos Retrospectivos , Fraturas da Ulna/diagnóstico por imagem , Adulto Jovem
2.
Orthop Traumatol Surg Res ; 103(5): 703-707, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28606840

RESUMO

BACKGROUND: Pilon variant posterior malleolar (PVPM) fractures significantly disrupt joint congruency and cause tibiotalar instability. They are often underestimated and inadequately treated. PURPOSE: This study assessed the outcomes of surgical treatment of this subtype of malleolar fracture, and examined the importance of computed tomography (CT) in diagnosis and surgical treatment. MATERIAL AND METHODS: CT images and radiographs of 67 patients with trimalleolar ankle fractures were retrospectively analyzed. Fourteen patients (6 women and 8 men) were studied. The mean age was 37.7 (range, 21-58) years, and mean follow-up period was 17.1 (range, 12-24) months. All patients underwent open reduction. Reconstruction of the joint surface was assessed with postoperative CT images. The outcomes were assessed with the American Academy of Orthopaedic Surgeons (AAOS) and Osteoarthritis (OA) scoring systems. RESULTS: The ratio of PVPM fractures to trimalleolar ankle fractures was 20.1%. Postoperative CT images demonstrated that anatomic reconstruction was achieved in 11 patients. The mean AAOS scores were 85.6 in Type 1 and 81.1 in Type 2 cases. The mean OA scores were 1 in Type 1 and 1.1 in Type 2 cases (P>0.05). The only statistically significant difference between the 2 groups was in osteochondral impaction (P<0.05). CONCLUSION: CT imaging is essential for the accurate diagnosis and management of PVPM fractures. Posteromedial and posterolateral incisions enable direct exposure, and therefore facilitate joint surface reconstruction. LEVEL OF EVIDENCE: Level IV. Retrospective study.


Assuntos
Fraturas do Tornozelo/cirurgia , Fraturas Intra-Articulares/cirurgia , Redução Aberta/métodos , Ossos do Tarso/lesões , Fraturas da Tíbia/cirurgia , Adulto , Fraturas do Tornozelo/classificação , Fraturas do Tornozelo/diagnóstico por imagem , Feminino , Fixação Interna de Fraturas , Humanos , Fraturas Intra-Articulares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Ossos do Tarso/diagnóstico por imagem , Fraturas da Tíbia/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto Jovem
3.
Cent Eur Neurosurg ; 71(2): 108-9, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20135585

RESUMO

As the use of instrumentation in spinal surgery has become common, the need for revision surgery has increased. During revision surgery one of the most difficult steps is removal of poly-axial pedicle screws, especially if no suitable revision set is available. We describe here an easy method for poly-axial screw removal. Leaving or placing a small piece of rod, attached firmly by a nut, tightens the head of the poly-axial screw. It can no longer move freely from the distal part of the screw and the screw can be removed by turning it counterclockwise with a big clamp or needle driver, which is available in almost every surgery set.


Assuntos
Parafusos Ósseos , Remoção de Dispositivo/métodos , Procedimentos Ortopédicos/instrumentação , Coluna Vertebral/cirurgia , Humanos , Reoperação
4.
Eur J Phys Rehabil Med ; 44(3): 237-44, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18469735

RESUMO

AIM: To evaluate the effects of ''Playstation EyeToy Games'' on upper extremity motor recovery and upper extremity-related motor functioning of patients with subacute stroke. METHODS: The authors designed a randomized, controlled, assessor-blinded, 4-week trial, with follow-up at 3 months. A total of 20 hemiparetic inpatients (mean age 61.1 years), all within 12 months post-stroke, received 30 minutes of treatment with ''Playstation EyeToy Games'' per day, consisting of flexion and extension of the paretic shoulder, elbow and wrist as well as abduction of the paretic shoulder or placebo therapy (watching the games for the same duration without physical involvement into the games) in addition to conventional program, 5 days a week, 2-5 hours/day for 4 weeks. Brunnstrom's staging and self-care sub-items of the functional independence measure (FIM) were performed at 0 month (baseline), 4 weeks (post-treatment), and 3 months (follow-up) after the treatment. RESULTS: The mean change score (95% confidence interval) of the FIM self-care score (5.5 [2.9-8.0] vs 1.8 [0.1-3.7], P=0.018) showed significantly more improvement in the EyeToy group compared to the control group. No significant differences were found between the groups for the Brunnstrom stages for hand and upper extremity. CONCLUSION: ''Playstation EyeToy Games'' combined with a conventional stroke rehabilitation program have a potential to enhance upper extremity-related motor functioning in subacute stroke patients.


Assuntos
Atividade Motora/fisiologia , Paresia/reabilitação , Recuperação de Função Fisiológica/fisiologia , Reabilitação do Acidente Vascular Cerebral , Extremidade Superior/fisiopatologia , Jogos de Vídeo , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Paresia/etiologia , Paresia/fisiopatologia , Desempenho Psicomotor/fisiologia , Método Simples-Cego , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/fisiopatologia , Resultado do Tratamento
5.
Anesth Analg ; 101(5): 1490-1491, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16244016

RESUMO

Risperidone is an atypical antipsychotic drug used for the treatment of schizophrenia. Both positive and negative symptoms are prominent with its use. Metabolism occurs mainly in the liver, where risperidone is changed by CUP2D6 to an active metabolite, 9-hydroxyrisperidone. The half-lives of risperidone and its metabolite are 3 and 7 h, respectively. Genetic polymorphism is seen in the 6%-8% of white patients who are considered poor metabolizers. In poor metabolizers, the half-life extends to 20-30 h. We present an unusual case of unanticipated delayed respiratory depression after risperidone overdose.


Assuntos
Antipsicóticos/intoxicação , Respiração/efeitos dos fármacos , Risperidona/intoxicação , Adulto , Overdose de Drogas , Feminino , Humanos , Fatores de Tempo
6.
Minim Invasive Neurosurg ; 48(3): 149-53, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16015491

RESUMO

A new rat model of the sacrifice of the anterior and posterior cortical anastomotic veins by the microsurgical technique was used to evaluate venous infarction. 20 male Sprague-Dawley rats were used in this experiment. Small burr-holes were done over the anterior and posterior anastomotic veins. After the precise description of these vessels, bipolar coagulation and micro-scissor was used for sacrifice. Specimens were evaluated by histopathological techniques. Hemispheric swelling, midline shift, brain edema, subcortical petechial hemorrhage, infarction and necrosis were histopathological findings on the microscopic examination. Our results revealed that the sacrifice of the anterior and posterior anastomotic veins was a very successful model in the evaluation of brain damage after the disturbance to the venous circulation.


Assuntos
Infarto Cerebral , Veias Cerebrais , Modelos Animais de Doenças , Microcirurgia/métodos , Procedimentos Neurocirúrgicos/métodos , Animais , Infarto Cerebral/patologia , Veias Cerebrais/patologia , Veias Cerebrais/cirurgia , Masculino , Ratos , Ratos Sprague-Dawley
7.
Minim Invasive Neurosurg ; 47(3): 169-72, 2004 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15343434

RESUMO

In spite of electrodiagnostic examinations, the determination of the precise localization of the injured site along the involved peripheral nerve may remain obscure or uncertain. Before starting the operation, a surgeon should have knowledge about the type of injury, the position of the proximal and distal nerve stumps, and the presence or absence of a neuroma and excessive perilesional scar tissue formation for orientation and planning of the surgical intervention. We hypothesized that real-time ultrasound could be helpful in the determination of the type of injury, the localisation of proximal and distal nerve stumps, as well as for diagnosing a neuroma. Fourteen patients with traumatic peripheral nerve injuries that were verified by neurological examinations and electrodiagnostic tests underwent surgical repair, and were examined by ultrasound before and during the surgical intervention. Visualisation of the injured site, the type of the injury, the position of the nerve stumps and the diagnosis of the neuroma were reliably feasible in all the patients by using ultrasonography. Axonal swelling of a nerve was diagnosed in 4 (29 %) patients, a stump neuroma was diagnosed in 3 (21 %) patients, a total nerve interruption (neurotmesis in the Seddon classification) was diagnosed in 9 (64 %) patients, and surrounding scar tissue was diagnosed in 5 (35 %) patients. Presurgical and intraoperative ultrasound-assisted neuroexamination is a useful diagnostic method in the determination of the precise localisation of the injured site, the type of injury, the position of stumps, and the diagnosis of a neuroma. The use of preoperative and intraoperative ultrasound can enhance the orientation of the surgeon to the surgical field. The application of our method to our patients shows that presurgical ultrasonographic neuroexamination can be used in the surgical repair of peripheral nerve injury.


Assuntos
Traumatismos dos Nervos Periféricos , Doenças do Sistema Nervoso Periférico/diagnóstico por imagem , Doenças do Sistema Nervoso Periférico/cirurgia , Ultrassonografia/métodos , Adolescente , Adulto , Axônios/patologia , Criança , Cicatriz , Eletrodiagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Monitorização Intraoperatória , Planejamento de Assistência ao Paciente , Nervos Periféricos/diagnóstico por imagem , Sensibilidade e Especificidade
8.
Minim Invasive Neurosurg ; 47(2): 127-9, 2004 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15257489

RESUMO

In spite of maximal microsurgical efforts, perilesional neural tissue can be injured by surgical instruments in the process of the separation and dissection of tumors. We hypothesized that transparent microballoon dissection could be helpful in the gentle separation of brain tissue from tumor by minimizing cerebral damage, and in separating sulcal and cisternal walls during surgical interventions on brain masses. We used the transparent microballoon dissection technique in 3 primary cases and 4 metastatic brain tumors that were verified with computed tomography (CT) and magnetic resonance imaging (MRI). Gentle separation of tumor from surrounding brain, reduction of cerebral damage, and separation of sulcal and cisternal walls were feasible in all patients. Postoperative CT and MRI showed satisfactory results in reducing perilesional cerebral damage. The transparent microballoon inflation technique is a useful microsurgical method for the gentle separation of tumors from surrounding brain tissue, minimizing cerebral damage, and separating sulcal and cisternal walls during surgical interventions for brain masses. Our conclusion is that using the microballoon dissection method may be suitable in microneurosurgical practice.


Assuntos
Neoplasias Encefálicas/cirurgia , Encéfalo/cirurgia , Dissecação/métodos , Microcirurgia/instrumentação , Microcirurgia/métodos , Complicações Pós-Operatórias/prevenção & controle , Adulto , Idoso , Encéfalo/patologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
9.
Minim Invasive Neurosurg ; 46(3): 169-72, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12872195

RESUMO

In this operative case-based report, we have investigated the ability and benefits of intraoperative grey-scale sonographic examination in the localising of arteriovenous malformations in the brain, the identification of feeding artery or arteries, the description of perilesional changes, and the detection of accompanying hematomas. The surrounding edematous brain tissue was observed as hyperechioc areas. The arteriovenous malformation appeared in two echogenic parts, a hyperechioc thrombotic part and a hypoechoic perfused part. We were able to identify the feeding artery. The sonographic characteristics of this artery are thick vascular wall, the presence of arterial systolic pulsation and a close relation with the nidus. We conclude that intraoperative ultrasonographic examination during the surgical treatment of arteriovenous malformation is a non-invasive, useful, and simple diagnostic tool in the detection of the components and accompanying parts of the lesion.


Assuntos
Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Malformações Arteriovenosas Intracranianas/cirurgia , Ultrassonografia de Intervenção/métodos , Adulto , Edema Encefálico , Artérias Cerebrais/diagnóstico por imagem , Artérias Cerebrais/patologia , Hematoma/diagnóstico por imagem , Hematoma/etiologia , Humanos , Masculino , Monitorização Intraoperatória
10.
Minim Invasive Neurosurg ; 46(2): 110-2, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12761683

RESUMO

We report two children with asymptomatic arachnoid cysts which resolved spontaneously without any surgical intervention and history of major head and body trauma. The first child was a 10-year-old boy with an arachnoid cyst in the right sylvian fissure. The second child was a 1-year-old girl with a right cerebral convexity arachnoid cyst. Both of them were asymptomatic. Arachnoid cysts spontaneously disappeared within 2 years following initial diagnosing. There was no major head and body trauma except usual home, school and sports activity. We speculated that the cysts ruptured into cerebrospinal fluid circulation by the mechanical effects of some forced activities to the brain tissue and cyst, such as excessive breathing, coughing and sport activities. These factors may change the balance between intracystic and pericystic pressure and facilitate the rupturing of the cyst into subdural, subarachnoid and intraventricular spaces. These cases demonstrate that neurosurgical intervention of asymptomatic arachnoid cysts is not absolutely indicated in the paediatric age group. Close follow up with computerized tomography (CT) and magnetic resonance imaging (MRI) is a treatment option in the patient with arachnoid cysts located in the middle cranial fossa and cerebral convexity.


Assuntos
Cistos Aracnóideos/diagnóstico por imagem , Cistos Aracnóideos/patologia , Cistos Aracnóideos/fisiopatologia , Criança , Feminino , Humanos , Lactente , Imageamento por Ressonância Magnética , Masculino , Remissão Espontânea , Fatores de Tempo , Tomografia Computadorizada por Raios X
11.
Minim Invasive Neurosurg ; 46(6): 361-2, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14968405

RESUMO

A 42-year-old male patient was surgically treated for two cerebral aneurysms, 18 months later he developed manifestations of Behçet's disease. Lack of clinical manifestations as well as angiographic evidence of vasculitis at the time of the cerebral aneurysmal disease argue against the possibility that the aneurysms were complications of the neural involvement of Behçet's disease.


Assuntos
Síndrome de Behçet/complicações , Aneurisma Intracraniano/complicações , Adulto , Síndrome de Behçet/diagnóstico , Humanos , Aneurisma Intracraniano/diagnóstico , Masculino
12.
Minim Invasive Neurosurg ; 46(6): 372-3, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14968409

RESUMO

Patients who underwent craniotomy occasionally complain about the postoperative cosmetic appearance at the site of burr holes on the scalp. This problem occurs as a result of depletion of the skin into the unreconstructed burr holes. Some materials have been developed for reconstruction of craniotomy burr holes. To prevent the postoperative cosmetic deformity, the authors developed a button-shaped autologous bone graft harvested from the inner table of craniotomy flap. Clinical application of this method is described.


Assuntos
Transplante Ósseo/métodos , Craniotomia/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Crânio/patologia , Crânio/transplante , Estruturas Criadas Cirurgicamente , Humanos , Transplante Autólogo
13.
J Neurosurg Sci ; 45(2): 97-102, 2001 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-11533534

RESUMO

Nine male patients with acute interhemispheric subdural hematoma (ISH) are presented. The etiologic factor was trauma for all patients (traffic accident and falling down). The young adult cases and one child had bad prognosis due to severe clinical findings and high mortality. The asymptomatic patients were treated conservatively. In this report, we discussed etiologic factors, presentation of age groups, whether an ISH progresses to a chronic convexity subdural hematoma (SH), and real mortality rates for ISH with relevant literature knowledge. As a result, ISHs can present in all age groups including shaken babies, severely injured young adults as well as low velocity trauma striken elderly patients (especially those under anticoagulant medication). We believe that an acute ISH does not change to chronic convexity SH; in fact they present as simultaneous acute thin convexity SH and acute ISH. It is also concluded that in contrast to previous literature ISH and acute SH patients of similar neurological status have similar mortality rates.


Assuntos
Lesões Encefálicas/complicações , Córtex Cerebral/irrigação sanguínea , Veias Cerebrais/lesões , Veias Cerebrais/patologia , Hematoma Subdural Agudo/etiologia , Hematoma Subdural Agudo/mortalidade , Doença Aguda , Adolescente , Adulto , Fatores Etários , Idoso , Anticoagulantes/efeitos adversos , Lesões Encefálicas/patologia , Lesões Encefálicas/fisiopatologia , Córtex Cerebral/patologia , Córtex Cerebral/fisiopatologia , Veias Cerebrais/diagnóstico por imagem , Evolução Fatal , Hematoma Subdural Agudo/patologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Prognóstico , Tomografia Computadorizada por Raios X , Resultado do Tratamento
14.
Acta Anaesthesiol Scand ; 45(6): 786-9, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11421842

RESUMO

BACKGROUND: Administration of bupivacaine caudally has been used for postoperative analgesia after urogenital, rectal and lower abdominal surgery in children. Caudal opioids may offer analgesic advantages over bupivacaine alone but have been associated with side effects such as respiratory depression. Tramadol is an analgesic assumed to lack a respiratory depressant effect and has been shown to provide effective, long-lasting analgesia after epidural administration in adults and children. The aim of this study was to determine whether the addition of tramadol to bupivacaine caudally prolongs the duration of analgesia compared with bupivacaine alone, with respect to side effects, and whether caudal tramadol alone provides satisfactory analgesia. METHODS: Sixty boys, aged 12-84 months, undergoing unilateral herniorrhaphy, were allocated randomly to three groups. Children in group B received 0.25% plain bupivacaine 1 ml kg(-1), group BT received an identical local anesthetic dose mixed with tramadol 1.5 mg kg(-1) and group T received caudal tramadol 1.5 mg kg(-1) in 0.9% sodium chloride in the same total volume (1 ml kg(-1)). Pain and demeanour assessments were made 1, 2, 3, 4, 6, 12 and 24 h after recovery from anesthesia with reference to a three-point scale. RESULTS: Analgesia time (time between caudal injection and first administration of analgesic) in group BT (13.5+/-2.2 h) was significantly longer than in the other two groups (P<0.05). In group T, more patients required additional analgesia after surgery than in the other two groups (P<0.05). Pain scores in the three groups were similar up to 4 h after operation but the mean score in group T was higher than groups B and BT 4 and 6 h after operation (P<0.05). Significantly more patients who had received caudal bupivacaine alone or with tramadol had lower pain and demeanour scores during the first 24 h after operation compared with those in the tramadol group. CONCLUSION: Caudal administration of bupivacaine with the addition of tramadol resulted in superior analgesia with a longer period without demand for additional analgesics compared with caudal bupivacaine and tramadol alone without an increase of side effects.


Assuntos
Analgésicos Opioides/uso terapêutico , Anestésicos Locais/uso terapêutico , Bupivacaína/uso terapêutico , Herniorrafia , Dor Pós-Operatória/tratamento farmacológico , Tramadol/uso terapêutico , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/efeitos adversos , Anestésicos Locais/administração & dosagem , Anestésicos Locais/efeitos adversos , Bupivacaína/administração & dosagem , Bupivacaína/efeitos adversos , Pré-Escolar , Quimioterapia Combinada , Frequência Cardíaca/efeitos dos fármacos , Humanos , Lactente , Masculino , Bloqueio Nervoso , Oximetria , Medição da Dor , Testes de Função Respiratória , Tramadol/administração & dosagem , Tramadol/efeitos adversos
16.
Acta Neurochir (Wien) ; 142(8): 929-33, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-11086833

RESUMO

Intra-operative cyst rupture is a catastrophic event in the intracranial hydatid cyst disease. Dissemination of the cyst contents may lead to severe anaphylactic reactions and an increased risk of recurrence. Several scolicidal agents have been used to eradicate the infective scolices but recurrences occur and no solution has been evaluated for its adverse effects to the brain tissue. Being a specific scolocidal agent albendazole has been shown to be 100% scolicidal in vitro. In this study, we present the electrophysiological and histopathological effects of intracerebral 2% albendazole injection in the rat brain. Vascular, neuronal and glial as well as inflammatory changes were evaluated in order to detect any adverse pharmacological effects. Electrophysiological and most microscopic parameters showed no significant effects attributable to albendazole but in 25% of the albendazole group cerebral gliosis was detected whereas no gliosis was present in the control group. It is concluded that being a specific scolicidal agent albendazole offers an efficient alternative for ruptured cerebral hydatid disease, but the significance and clinical importance of the gliosis should be further investigated.


Assuntos
Albendazol/efeitos adversos , Anticestoides/efeitos adversos , Encéfalo/efeitos dos fármacos , Encéfalo/patologia , Neurocisticercose/tratamento farmacológico , Neurocisticercose/cirurgia , Albendazol/administração & dosagem , Animais , Anticestoides/administração & dosagem , Encéfalo/parasitologia , Relação Dose-Resposta a Droga , Gliose/induzido quimicamente , Instilação de Medicamentos , Masculino , Neurocisticercose/patologia , Ratos , Ratos Wistar
17.
J Egypt Soc Parasitol ; 27(2): 445-54, 1997 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-9257983

RESUMO

Adenosine deaminase (ADA) activities in serum samples, erythrocytes, leukocytes and plasma hemoglobin concentrations were investigated in 50 patients with vivax malaria and compared with control group. ADA activity was determined by Bertholet reaction. Student's t-test and correlation analyses methods were used for statistical analyses. Serum ADA activity in patients with vivax malaria 49.20 +/- 29.02 IU/I, in control 21.15 +/- 8.04 IU/I (p = 0.005), erythrocyte ADA activity in patients 2.91 +/- 1.23 U/gr Hb, in control 1.65 +/- 0.59 U/gr (p = 0.001), leukocyte specific ADA activity in patients 26.23 +/- 20.21 U/mg protein, in control 25.84 +/- 9.19 U/gr Hb were determined (P > 0.05). Plasma hemoglobin concentration in patients 29.25 +/- 28.10 ml/dl, in control 9.80 +/- 13.14 mg/dl were also determined. There is no significant correlation among mentioned parameters. Erythrocyte purine salvage pathway is accelerated by Plasmodium to provide preformed purine source which can not be synthesized by Plasmodium to provide preformed purine source which can correlation between plasma hemoglobin concentration and serum ADA activity suggests that increased serum ADA activity may develop secondarily to the disease independently from the hemolyses. No higher ADA activity level than expected value of leukocytes may reflect immunosuppression of leukocytes.


Assuntos
Adenosina Desaminase/sangue , Eritrócitos/enzimologia , Leucócitos/enzimologia , Malária Vivax/sangue , Adolescente , Adulto , Hemoglobinas/metabolismo , Humanos , Malária Vivax/enzimologia , Valores de Referência , Turquia
18.
Middle East J Anaesthesiol ; 13(6): 605-11, 1996 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-8987040

RESUMO

We have assessed tracheal intubating conditions in 45 ASA I-II children, aged 4-14 years, undergoing elective ear, nose and throat surgery. After the induction dose of propofol 2.5 mgkg-1, Group I received alfentanil 10 ugkg-1, Group II received alfentanil 20 ugkg-1 and Group III received atracurium 0.5 mgkg-1 for tracheal intubation. The mean arterial pressure (MAP), heart rate (HR), arterial oxygen saturation (SaO2), end tidal carbondioxide (ETCO2) and intubation conditions were investigated. The quality of tracheal intubation was graded according to ease of laryngoscopy, position of the vocal cords, coughing and jaw relaxation. There were no significant differences in the overall assessment of intubating conditions between the three groups. Intubations were accomplished in 94% of the patients in Group I and II, and 100% of the patients in Group III. We conclude that the combination of propofol and alfentanil conditions for treacheal intubation in children and attenuate the hemodynamic responses to layngoscopy and tracheal intubation.


Assuntos
Alfentanil , Anestésicos Intravenosos , Atracúrio , Intubação Intratraqueal , Fármacos Neuromusculares não Despolarizantes , Propofol , Adolescente , Alfentanil/administração & dosagem , Alfentanil/farmacologia , Anestésicos Intravenosos/administração & dosagem , Anestésicos Intravenosos/farmacologia , Atracúrio/administração & dosagem , Atracúrio/farmacologia , Criança , Pré-Escolar , Procedimentos Cirúrgicos Eletivos , Hemodinâmica/efeitos dos fármacos , Humanos , Fármacos Neuromusculares não Despolarizantes/administração & dosagem , Fármacos Neuromusculares não Despolarizantes/farmacologia , Propofol/administração & dosagem , Propofol/farmacologia
20.
Neuroradiology ; 36(1): 54-5, 1994.
Artigo em Inglês | MEDLINE | ID: mdl-8107999

RESUMO

We reviewed the computed tomographic (CT) studies of 105 adults with various complaints. Spinal canal diameters were measured by CT using both the conventional and Jones-Thomson (JT) techniques at the level of the fourth lumbar vertebra. The data were statistically assessed in an attempt to define spinal stenosis.


Assuntos
Vértebras Lombares/diagnóstico por imagem , Canal Medular/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência , Estenose Espinal/diagnóstico por imagem
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