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1.
Biol Trace Elem Res ; 190(1): 282, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30255338

RESUMO

The original version of this article unfortunately contained a mistake. The name of "Herlambang herlambang" is now corrected in the author group of this article.

2.
BMC Res Notes ; 10(1): 683, 2017 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-29202851

RESUMO

BACKGROUND: Female genital tuberculosis (FGTB) is a Mycobacterium infection in the reproductive organs which often leads to infertility. FGTB is either asymptomatic or causes uncharacteristic clinical presentations, making an early diagnosis is challenging. Our aims were to evaluate the clinical presentations, the process to confirm the diagnosis and followed-up the patients who had undergone laparoscopy at our center. FGTB has been reported from many countries, but has never been reported from Indonesia. Here we present case studies to document the presence of FGTB in Indonesia. CASES PRESENTATION: There were three patients admitted to our center; two patients were admitted with irregular menstrual cycle as their chief complaint, while one patient came due to infertility. The results from laparoscopy were suggestive of FGTB; including the presence of caseating granulomas surrounded by epithelioid cells, lymphocytes, plasma cells, and Langhans giant cells. Additionally, PCR testing confirmed presence of MTB. Subsequent to diagnosis, continuous TB medications was administered with excellent clinical outcome in two patients (pregnant in 18 months after under gone laparoscopy). The infertile patient remain in one of the treated patient above. CONCLUSION: In infertile patients who live in countries where Tuberculosis is an endemic disease, such as Indonesia, a comprehensive history taking, along with ultrasonography results can be used to diagnose FGTB. Confirmation of this diagnosis can be achieved through polymerase chain reactions result. Timely diagnosis and treatment are imperative to prevent any permanent injury to patient's reproductive organs.


Assuntos
DNA Bacteriano/genética , Granuloma/diagnóstico por imagem , Distúrbios Menstruais/diagnóstico por imagem , Mycobacterium tuberculosis/genética , Tuberculose dos Genitais Femininos/diagnóstico por imagem , Adulto , Feminino , Granuloma/microbiologia , Granuloma/patologia , Humanos , Indonésia , Infertilidade Feminina , Laparoscopia , Distúrbios Menstruais/microbiologia , Distúrbios Menstruais/patologia , Mycobacterium tuberculosis/isolamento & purificação , Reação em Cadeia da Polimerase , Gravidez , Tuberculose dos Genitais Femininos/microbiologia , Tuberculose dos Genitais Femininos/patologia , Ultrassonografia
3.
Biol Trace Elem Res ; 154(1): 1-6, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23695728

RESUMO

Selenium is an essential nutrient for human health, and maternal selenium concentration has been reported to be associated with pregnancy outcome. To further investigate the possible role of selenium (Se) in miscarriage, we conducted a case-control study to evaluate the correlations among selenium status, glutathione peroxidase activity, and spontaneous abortion. A total of 46 subjects with normal pregnancies and 25 subjects with spontaneous abortion were recruited, and their serum selenium concentrations and serum glutathione peroxidase activities were analyzed. The total serum selenium concentrations in subjects with normal pregnancies were significantly higher than those of subjects with spontaneous abortion; however, the glutathione peroxidase activities were similar in both groups. We further separated the subjects into smoking and nonsmoking groups, and the logistic regression analysis suggested that total serum selenium concentration, but not serum glutathione peroxidase activity or smoking, was significantly correlated with the incidence of miscarriage. The present study thus reaffirms that low serum selenium levels are associated with miscarriage and that selenium plays an important role in pregnancy maintenance.


Assuntos
Aborto Espontâneo/sangue , Selênio/sangue , Aborto Espontâneo/enzimologia , Adulto , Estudos de Casos e Controles , Feminino , Glutationa Peroxidase/sangue , Humanos , Indonésia , Gravidez , Fumar/efeitos adversos
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