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1.
Heliyon ; 10(15): e34622, 2024 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-39144992

RESUMO

Protein compartmentalization in the frame of a liquid-liquid phase separation is a key mechanism to optimize spatiotemporal control of biological systems. Such a compartmentalization process reduces the intrinsic noise in protein concentration due to stochasticity in gene expression. Employing Flory-Huggins solution theory, Avramov/Casalini's model, and the Grüneisen parameter, we unprecedentedly propose a cellular Griffiths-like phase (CGLP), which can impact its functionality and self-organization. The here-proposed CGLP is key ranging from the understanding of primary organisms' evolution to the treatment of diseases. Our findings pave the way for an alternative Biophysics approach to investigate coacervation processes.

2.
Sci Rep ; 11(1): 9431, 2021 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-33941810

RESUMO

The temperature change under adiabatic stress, i.e., the elastocaloric effect, is a well-understood phenomenon and of particular interest due to its potential application in alternative ways for refrigeration. Here, we demonstrate that in the regime of low-temperatures (a few mK) real paramagnets can be magnetized when compressed adiabatically without applied magnetic field. Such adiabatic magnetization is a genuine many-body problem, stemming from the inherent dipolar mutual interactions between adjacent magnetic moments. We showcase experimental setups to carry out adiabatic magnetization and thus to access such a subtle effect. Perspectives of further investigations by controlling the mutual interactions in Bose-Einstein condensates in magnetic insulators and dipolar spin-ice systems via the adiabatic increase of temperature are also presented. Yet, we discuss the connection between the elastic Grüneisen parameter and the shift on the critical temperature of second-order phase transitions under adiabatic stress, as well as its connection with the Ehrenfest relation.

3.
Physica A ; 573: 125963, 2021 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-33814681

RESUMO

We revisit well-established concepts of epidemiology, the Ising-model, and percolation theory. Also, we employ a spin S = 1/2 Ising-like model and a (logistic) Fermi-Dirac-like function to describe the spread of Covid-19. Our analysis show that: (i) in many cases the epidemic curve can be described by a Gaussian-type function; (ii) the temporal evolution of the accumulative number of infections and fatalities follow a logistic function; (iii) the key role played by the quarantine to block the spread of Covid-19 in terms of an interacting parameter between people. In the frame of elementary percolation theory, we show that: (i) the percolation probability can be associated with the probability of a person being infected with Covid-19; (ii) the concepts of blocked and non-blocked connections can be associated, respectively, with a person respecting or not the social distancing. Yet, we make a connection between epidemiological concepts and well-established concepts in condensed matter Physics.

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