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Respir Physiol Neurobiol ; 325: 104268, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38679307

RESUMO

Obstructive sleep apnea (OSA) patients who use continuous positive airway pressure (CPAP) often complain of nasal dryness and nasal obstruction as side effects of CPAP. The physiological mechanisms by which CPAP may cause nasal dryness and nasal obstruction remain poorly understood. It has been hypothesized that CPAP interferes with the nasal cycle, abolishing the resting phase of the cycle and leading to nasal dryness. We performed rhinomanometry measurements in 31 OSA patients sitting, laid supine, and supine after 10 min of CPAP at 10 cmH2O. A posture change from sitting to supine led to more symmetric airflow partitioning between the left and right nostrils in the supine position. CPAP did not have a significant impact on nasal resistance, unilateral airflows, or airflow partitioning. Our results suggest that airflow partitioning becomes more symmetric immediately after changing to a supine position, while CPAP had no effect on nasal airflow, thus preserving the nearly symmetric airflow partitioning achieved after the posture change.


Assuntos
Pressão Positiva Contínua nas Vias Aéreas , Postura , Rinomanometria , Apneia Obstrutiva do Sono , Humanos , Masculino , Postura/fisiologia , Feminino , Pessoa de Meia-Idade , Apneia Obstrutiva do Sono/terapia , Apneia Obstrutiva do Sono/fisiopatologia , Adulto , Resistência das Vias Respiratórias/fisiologia , Obstrução Nasal/fisiopatologia , Obstrução Nasal/terapia , Decúbito Dorsal/fisiologia , Idoso
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