1.
Vopr Onkol
; 53(5): 575-7, 2007.
Artigo
em Russo
| MEDLINE
| ID: mdl-18154124
RESUMO
Three regimes of combined treatment for intraoral and oropharyngeal cancer were compared. In group A, cisplatin 6 mg/m2 was given intravenously, daily; group B--40 mg/m2, weekly; group C--100 mg/m2, once in 3 weeks. All patients simultaneously received distant radiation therapy in a standard fractionated dose of 2 Gy per fraction, 5 times a week, up to TTD of 68-70 Gy. Among relatively frequent side-effects were granulocytopenia, asthenia and stomatitis. Overall immediate effectiveness was: group A--100%, group B--96% and group C--100%. The rates of complete tumor resorption were: group A--27.3%, group B--19.2% and group C--16.7%.
Assuntos
Antineoplásicos/uso terapêutico , Cisplatino/uso terapêutico , Neoplasias Bucais/tratamento farmacológico , Neoplasias Bucais/radioterapia , Neoplasias Orofaríngeas/tratamento farmacológico , Neoplasias Orofaríngeas/radioterapia , Adulto , Agranulocitose/etiologia , Astenia/etiologia , Quimioterapia Adjuvante , Fracionamento da Dose de Radiação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radioterapia Adjuvante , Estomatite/etiologia , Resultado do Tratamento
2.
Vestn Ross Akad Med Nauk
; (3): 51-3, 2002.
Artigo
em Russo
| MEDLINE
| ID: mdl-11989293