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1.
J Otolaryngol Head Neck Surg ; 49(1): 52, 2020 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-32703280

RESUMO

BACKGROUND: Operating room (OR) efficiency is related to minutes spared from surgical time and has been linked to the make up of surgical teams and operating room workplace. The research on the efficiency of surgical nursing staff members is scant. The current study evaluates the effect of ENT trained OR resource nurses on the efficiency of operating time during ENT procedures. METHODS: Five hundred seventy-three ENT surgery cases from 4 surgeons were retrospectively reviewed. Two hundred forty-two cases had ENT OR nursing staff and 331 cases had non-ENT OR nursing staff. Requested operative times (ROT) and true operative times (TOT) were analyzed. The difference between the TOT and ROT was used to measure operating time efficiency. RESULTS: Cases with ROT < 30 min (M = -1.19, SD = 5.01) required 3.34 min less than planned for when an ENT nurse was present compared to those with non-ENT nursing staff which required on average 2.15 min (M = 2.15, SD = 5.68) longer than ROT. Furthermore, cases with ROT > 30 min (M = -4.32, SD = 10.85) required 10.85 min less than planned for when an ENT nurse was present. Conversely with non-ENT nursing staff cases with a ROT > 30 min required on average 6.53 min (M = 6.53, SD = 11.85) longer than ROT. CONCLUSION: ENT resource nurses were shown to improve OR efficiency in cases less than 30 min and greater than 30 min. Cases that were greater than 30 min showed the largest increase in efficiency. Specialized ENT nursing staff improved efficiency during common ENT surgeries.


Assuntos
Eficiência Organizacional , Enfermagem de Centro Cirúrgico , Salas Cirúrgicas/organização & administração , Análise de Variância , Humanos , Duração da Cirurgia , Otolaringologia , Equipe de Assistência ao Paciente , Estudos Retrospectivos
2.
J Otolaryngol Head Neck Surg ; 48(1): 38, 2019 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-31426857

RESUMO

BACKGROUND: The natural history of patients diagnosed with Eisenmenger's Syndrome typically revolve around the pediatric population. Medical advances have allowed these patients to live longer and present with a different subset of symptoms as a result of the progression of their disease process. CASE PRESENTATION: In this case report, we discuss a 77-year-old Caucasian female with Eisenmenger's Syndrome presenting with hoarseness. Clinical and imaging studies reveal a left vocal cord paralysis secondary to a progressively enlarging patent ductus arteriosus (PDA) and dilation of pulmonary arteries causing mass effect on the left recurrent laryngeal nerve. CONCLUSION: From a clinical perspective, this case highlights the need for otolaryngologists to be aware of the pathophysiology of Eisenmenger's Syndrome as it progresses with age.


Assuntos
Complexo de Eisenmenger/fisiopatologia , Rouquidão/fisiopatologia , Idoso , Complexo de Eisenmenger/diagnóstico por imagem , Feminino , Rouquidão/diagnóstico por imagem , Humanos
3.
Oncol Rep ; 18(1): 93-7, 2007 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-17549352

RESUMO

N-myristoyltransferase (NMT) catalyzes the myristoylation of proteins involved in signal transduction, cellular transformation, differentiation, proliferation and oncogenesis. In this study, we report for the first time on the elevated NMT activity in oral squamous cell carcinoma (OSCC). Increased activity is marked with increased staining for NMT in the OSCC samples compared to the normal adjacent tissues. In addition, we observed increased staining for the N-myristoyltransferase inhibitor protein 71 (NIP71) in the OSCC samples compared to the control tissues. These findings suggest the regulatory relationship between NMT and NIP71 during tumorigenesis. It is possible that the increased activity results in the overexpression of NIP71 in an effort to control NMT activity.


Assuntos
Aciltransferases/metabolismo , Carcinoma de Células Escamosas/enzimologia , Neoplasias Bucais/enzimologia , Proteínas de Neoplasias/metabolismo , Carcinoma de Células Escamosas/patologia , Estudos de Casos e Controles , Regulação Neoplásica da Expressão Gênica , Humanos , Mucosa Bucal/enzimologia , Mucosa Bucal/patologia , Neoplasias Bucais/patologia , Ácido Mirístico/metabolismo , Processamento de Proteína Pós-Traducional
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