[Improving the system of preventing vibration and noise-induced pathology]. / Sovershenstvovanie sistemy profilaktiki vibratsionno-shumovoi patologii.

Due to the long-term study of various machines under industrial and test conditions it became possible to determine the specific role of each chain of the man-machine system in the intensification of vibroacoustic effect on a worker and to develop a system of medical, technical and organizational preventive measures. Introduction of a set of such measures at one of the plants helped to reduce vibration disease rates by dozens of times. In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.

[Pharmacokinetics of ampicillin in patients with chronic renal insufficiency during hemodialysis and hemosorption]. / Farmakokinetika ampitsillina u bol'nykh khronicheskoi pochechnoi nedostatochnost'iu v usloviiakh gemodializa i gemosorbtsii.

It was shown that when the filtration capacity of the kidneys was lowered even insignificantly (the creatinine clearance 50-80 ml/min), the maximum blood levels of ampicillin increased 2 times and its retention time was prolonged. At the terminal stage of chronic renal insufficiency the half-life of the drug and the area under the pharmacokinetic curve markedly increased and the plasma clearance decreased. Hemodialysis and hemosorption significantly lowered the ampicillin half-life. The ampicillin coefficient in hemosorption was 2 times higher than that in hemodialysis.