1.
Adv Exp Med Biol
; 691: 421-31, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21153347
Assuntos
Modelos Animais de Doenças , Fator de Necrose Tumoral alfa/antagonistas & inibidores , Animais , Encefalomielite Autoimune Experimental/imunologia , Encefalomielite Autoimune Experimental/patologia , Hepatite/imunologia , Hepatite/patologia , Humanos , Tecido Linfoide/imunologia , Tecido Linfoide/patologia , Camundongos , Choque Séptico/imunologia , Choque Séptico/patologia , Fator de Necrose Tumoral alfa/biossíntese
2.
Biochemistry (Mosc)
; 73(5): 562-72, 2008 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18605981
RESUMO
The appearance of antibodies to cancer-associated antigens in biological fluids (particularly, in blood sera) of cancer patients is now a well-established fact, and their detection by immunochemical methods is a promising approach to diagnostics of malignant neoplasms. In this review, we consider some immunobiological aspects of the most extensively studied cancer-associated B-cell antigens, various applications of autoantibodies as cancer biomarkers, and prospects for the use of antigen arrays for improving diagnostic sensitivity.
