1.
J Pept Sci
; 27(11): e3358, 2021 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34121261
RESUMO
Hydrophobic latent C-terminal thioesters were converted into thioesters, and were also coupled with cysteine in one-pot reactions, using conditions generally compatible with hydrophobic materials. The reaction conditions (ethanethiol and triethylamine in a mixture of DMF and THF) are compatible with acid-labile protecting groups (Boc/t-Bu) that are standard in Fmoc peptide synthesis.