[Various indicators of serotonin metabolism in the cerebrospinal fluid of patients with neurasthenia and cerebral arachnoiditis]. / Nekotorye pokazateli obmena serotonina v likvore bol'nykh nevrasteniei i tserebral'nym arakhnoiditom.

Thirty patients with cerebral arachnoiditis and 26 with neurasthenia were found to have differences in the content of serotonin, 5-hydroxyindoleacetic++ acid and melatonin in the cerebrospinal fluid, which depended in arachnoiditis on the degree of intracranial pressure elevation. The data on serotonin metabolism can be used in objective evaluation of the organic background in neurotic patients and serve for estimating the intensity of hypertension in patients with cerebral arachnoiditis.

[Serotonin and kinins in the cerebrospinal fluid in brain tumors]. / Serotonin i kininy likvora pri opukholiakh golovnogo mozga.

Concentrations of serotonin, 5-hydroxyindoleacetic acid, melatonin and parameters of the kinin system in the cerebrospinal fluid were monitored in 109 cases of brain tumor. All the levels were increased prior to surgery but returned to normal postoperatively unless disease followed an unfavorable course. It was suggested that the above-mentioned physiologically active substances play a certain role in compensatory mechanisms assuring recovery of CNS function.

[The pseudotumorous course of ischemic myelopathies]. / Psevdotumoroznoe techenie ishemicheskikh mielopatii.

Study of 36 cases of ischemic myelopathy following a pseudotumorous course and 30 cases of spinal cord tumors revealed similarity and differences in the clinical manifestations which should be taken into account in differential diagnosis. Authentic differences in the content of serotonin and its metabolites in the cerebrospinal fluid and blood of this group of patients are pointed out.

[Clinico-electromyographic indicators in patients with ischemic myelopathy]. / Kliniko-élektromiograficheskie pokazateli u bo'lnykh s ishemicheskoi mielopatiei.

Electromyography, electroneuromyography and monosynaptic N-reflex studies were performed in 61 patients with ischemic myelopathy. These data can be used to specify localization and the extent of the process. Its differentiation with several diseases providing a phenocopy of spinal disorders (tumors, lateral amyotrophic sclerosis syringomyelia, funicular myelosis) is discussed. The results of the study are important for evaluation of the extent of motor disorders compensation states in disabled functions, and hence, the patients' working capabilities.

[Serotonin and its metabolites in the cerebrospinal fluid and blood of patients with tumors of the spinal cord]. / Serotonin i ego metabolity v likvore i krovi bol'nykh s opukholiami spinnogo mozga.

Twenty-six patients with extra- and intramedullary tumors of the spinal cord had a considerably increased content of serotonin, 5-hydroxyindoleacetic acid, and melatonin in the cerebrospinal fluid (highest in patients with total blockade of the subarachnoid space) as well as of serotonin in blood platelets. The results of tests for serotonin metabolism can be used as a diagnostic test in the early stages of the tumor growth and are an additional factor in determining the indications for contrast examination of patients with a suspected spinal tumor.