1.
J Org Chem
; 75(16): 5764-7, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20666429
RESUMO
The total synthesis of batatoside L (1), a resin glycoside possessing cytotoxicity against laryngeal carcinoma cells, has been completed in a highly convergent manner. The most crucial step in this total synthesis was the efficient construction of the 18-membered macrolactone framework through the Corey-Nicolaou macrolactonization approach.
Assuntos
Convolvulaceae/química , Oligossacarídeos/síntese química , Resinas Vegetais/síntese química , Substâncias Macromoleculares/síntese química , Substâncias Macromoleculares/química , Conformação Molecular , Oligossacarídeos/química , Resinas Vegetais/química , Estereoisomerismo
2.
Carbohydr Res
; 344(15): 2063-8, 2009 Oct 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19709649
RESUMO
A protected trisaccharide imidate, 2,3-di-O-acetyl-4,6-O-benzylidene-beta-d-glucopyranosyl-(1-->3)-2-O-chloroacetyl-3-O-benzyl-4-isobutyryl-alpha-l-rhamnopyranosyl-(1-->4)-2-O-isobutyryl-alpha-l-rhamnopyranosyl trichloroacetimidate (1), has been synthesized by a block synthesis approach. Compound 1 can serve as a key intermediate in the total synthesis of resin glycoside merremoside H(2).
