RESUMO
A child in early puberty, who presented with a modestly enlarged thyroid gland and confirmed hypothyroidism, was successfully treated with thyroxine. Subsequently a widespread bruit developed in the neck caused by bilaterally dilated superior thyroid arteries with increased blood flow to the goitre. At thyroidectomy, histopathology showed features of dyshormonogenesis with greatly increased vascularity and widespread diffuse staining for vascular endothelial growth factor (VEGF). It is likely that VEGF in association with other angiogenetic factors was associated with enlargement of the gland and its hypervascularity.
Assuntos
Bócio/complicações , Hipotireoidismo/complicações , Glândula Tireoide/irrigação sanguínea , Criança , Feminino , Bócio/cirurgia , Humanos , Pescoço/irrigação sanguínea , Neovascularização Patológica , Fluxo Sanguíneo Regional , Glândula Tireoide/cirurgia , Tireoidectomia , Fator A de Crescimento do Endotélio Vascular/análiseRESUMO
Acute pancreatitis is more common in childhood than has been appreciated previously. During acute attacks of pancreatitis, hyperglycaemia and glycosuria are not uncommon but permanent diabetes mellitus is rare. Acute pancreatitis can also be associated with diabetic ketoacidosis and the association between these two is of a two-way cause and effect relationship. Early imaging of the pancreas is recommended in children with severe prolonged abdominal pain.
Assuntos
Diabetes Mellitus/tratamento farmacológico , Pancreatite/complicações , Doença Aguda , Adolescente , Complicações do Diabetes , Feminino , Humanos , Insulina/administração & dosagemRESUMO
We conducted a study to determine the prevalence and clinical patterns of footwear dermatitis, patch testing 50 patients with suspected footwear dermatitis and 30 controls with 22 allergens of a shoe series (Chemotechnique Diagnostics AB, Malmö, Sweden). The overall prevalence among contact dermatitis cases was 11.7%. The dorsa of the feet and toes were the commonest sites involved. 70% of patients showed sensitivity to footwear allergen(s), as opposed to 6.67% of controls. Potassium dichromate and colophony were the commonest sensitizers. Other sensitizers were the rubber accelerators 2-mercaptobenzothiazole (MBT) and diphenylguanidine (DPG) and a dye p-aminoazobenzene. Of the 23 patients patch tested with pieces or scrapings of footwear, only 3 showed positive reactions. We recommend that there should be primary and secondary footwear screening series to detect the responsible allergens, with the ultimate objective of providing correct nonallergenic footwear for our patients, with the help of manufacturers and research institutes.
Assuntos
Dermatite Alérgica de Contato/epidemiologia , Dermatoses do Pé/epidemiologia , Sapatos , Adolescente , Adulto , Alérgenos/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/etiologia , Feminino , Dermatoses do Pé/induzido quimicamente , Dermatoses do Pé/diagnóstico , Humanos , Masculino , Testes do Emplastro , PrevalênciaRESUMO
Exposure time of sunlight for PUVASOL is often arbitrarily determined. This,can-lead to either inadequate or over-exposure,. We, have evolved a computer programme, from which the exposure time can be determined. The programme, takes into consideration the, variations of UV light at different times of the day. We hove to extend this pilot study to various places in India.
RESUMO
A patient having contact dermatitis due to nickel on the wrist, sides of neck, thighs and legs, confirmed by patch tests with nickel sulphate, showed aggravation of the dermatitis following oral provocation with 25 mg nickel sulphate.
