RESUMO
The changes of external respiration indices in the patients suffering hepatic cirrhosis, complicated by ascitis and portal hypertension, were studied. Application of method of the ascitic liquor extracorporeal ultrafiltration and sorption with its subsequent return into venous system was proposed. The morphological changes of pulmonary parenchyma, which coincided with lowering of the external respiration indices in the patients, were studied.
Assuntos
Ascite/fisiopatologia , Hipertensão Portal/fisiopatologia , Hipertensão Pulmonar/fisiopatologia , Cirrose Hepática/fisiopatologia , Fenômenos Fisiológicos Respiratórios , Adulto , Ascite/complicações , Ascite/cirurgia , Feminino , Humanos , Hipertensão Portal/complicações , Hipertensão Portal/cirurgia , Hipertensão Pulmonar/etiologia , Cirrose Hepática/complicações , Cirrose Hepática/cirurgia , Masculino , Pessoa de Meia-Idade , Derivação Peritoneovenosa , Resultado do TratamentoRESUMO
New method of extracorporeal detoxication of organism, which is applied for temporary restoration of hepatic detoxication function in patients with hepatic insufficiency, albumin-mediated peritoneal dialysis, was presented. The main principle of this technology is a transfer through highly permeable dialysis membrane of toxins, which are in affinity with albumin, from the blood to acceptor. The donor's human albumin, circulating in the closed contour, serves as acceptor. The watersoluble lowmolecular substances are excreted according to the concentration gradient. For rapid restoration of acceptoral ability of the donor's albumin solution it was subjected to hemodialysis and carboperfusion. The performance of the procedure guarantees excretion of toxins, combined with albumin, along with excretion of watersoluble toxins.
