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1.
Biology (Basel) ; 12(12)2023 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-38132336

RESUMO

Geloina erosa is an important benthic animal in the mangrove, serving as an indicator organism for coastal environmental pollution. This study aimed to investigate the tissue-specific expression of miRNAs and their regulatory roles in predicted targets in G. erosa. Through miRNA sequencing and co-expression network analysis, we extensively studied the miRNA expression in three tissues: gills, hepatopancreas, and muscle. The results revealed a total of 1412 miRNAs, comprising 1047 known miRNAs, and 365 newly predicted miRNAs. These miRNAs exhibited distinct tissue-specific expression patterns. In the miRNA target gene prediction, a total of 7404 potential predicted targets were identified, representing approximately 33% of all unique transcripts associated with miRNAs. Further co-expression network analysis revealed nine modules, each showing a positive correlation with specific tissues (gills, hepatopancreas, or muscle). The blue module showed a significant correlation with gills (r = 0.83, p-value = 0.006), the black module was significantly related to the hepatopancreas (r = 0.78, p-value = 0.01), and the purple module was significantly correlated with muscle (r = 0.83, p-value = 0.006). Within these modules, related miRNAs tended to cluster together, while their correlations with other modules were relatively weak. Functional enrichment analysis was performed on miRNAs and their predicted targets in each tissue. In the gills, miRNAs primarily regulate immune-related genes, substance transport, and cytoskeletal organization. In the hepatopancreas, miRNAs suppressed genes involved in shell formation and played a role in cellular motor activity and metabolism. In muscle, miRNAs participate in metabolism and photoreceptive processes, as well as immune regulation. In summary, this study provides valuable insights into the tissue-specific regulation of miRNAs in G. erosa, highlighting their potential roles in immune response, metabolism, and environmental adaptation. These findings offer important clues for understanding the molecular mechanisms and biological processes in G. erosa, laying the foundation for further validation and elucidation of these regulatory relationships.

2.
Front Neurorobot ; 17: 1267231, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37885769

RESUMO

In light of advancing socio-economic development and urban infrastructure, urban traffic congestion and accidents have become pressing issues. High-resolution remote sensing images are crucial for supporting urban geographic information systems (GIS), road planning, and vehicle navigation. Additionally, the emergence of robotics presents new possibilities for traffic management and road safety. This study introduces an innovative approach that combines attention mechanisms and robotic multimodal information fusion for retrieving traffic scenes from remote sensing images. Attention mechanisms focus on specific road and traffic features, reducing computation and enhancing detail capture. Graph neural algorithms improve scene retrieval accuracy. To achieve efficient traffic scene retrieval, a robot equipped with advanced sensing technology autonomously navigates urban environments, capturing high-accuracy, wide-coverage images. This facilitates comprehensive traffic databases and real-time traffic information retrieval for precise traffic management. Extensive experiments on large-scale remote sensing datasets demonstrate the feasibility and effectiveness of this approach. The integration of attention mechanisms, graph neural algorithms, and robotic multimodal information fusion enhances traffic scene retrieval, promising improved information extraction accuracy for more effective traffic management, road safety, and intelligent transportation systems. In conclusion, this interdisciplinary approach, combining attention mechanisms, graph neural algorithms, and robotic technology, represents significant progress in traffic scene retrieval from remote sensing images, with potential applications in traffic management, road safety, and urban planning.

3.
PLoS One ; 18(9): e0290995, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37756278

RESUMO

According to the World Health Organization, cardiovascular diseases are the leading cause of deaths globally. Electrocardiogram (ECG) is a non-invasive approach for detecting heart diseases and reducing the risk of heart disease-related death. However, there are limited numbers of ECG samples and imbalance distribution for existing ECG databases. It is difficult to train practical and efficient neural networks. Based on the analysis and research of many existing ECG databases, this paper conduct an in-depth study on three fine-labeled ECG databases, to extract heartbeats, unify the sampling frequency, and propose a self-processing method of heartbeats, and finally form a unified ECG arrhythmia classification database, noted as Hercules-3. It is separated into training sets (80%) and testing sets (the remaining 20%). In order to verify its capabilities, we have trained a 16-classification fully connected neural network based on Hercules-3 and it achieves an accuracy rate of up to 98.67%. Compared with other data processing, our proposed method improves classification recall by at least 6%, classification accuracy by at least 4%, and F1-score by at least 7%.


Assuntos
Doenças Cardiovasculares , Cardiopatias , Humanos , Arritmias Cardíacas/diagnóstico , Bases de Dados Factuais , Eletrocardiografia
4.
Nanomaterials (Basel) ; 12(19)2022 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-36234469

RESUMO

Regardless of its good electron-transfer ability and chemical stability, pure Zn2SnO4 (ZSO) still has intrinsic deficiencies of a narrow spectral response region, poor absorption ability, and high photo-activated carrier recombination rate. Aiming to overcome the deficiencies above-mentioned, we designed a facile hydrothermal route for etching ZSO nanoparticles in a dilute acetic acid solution, through which efficient oxygen vacancy defect engineering was accomplished and SnO2-x nanocrystals were obtained with an ultrafine particle size. In comparison with the untreated ZSO nanoparticles, the specific surface area of SnO2-x nanocrystals was substantially enlarged, subsequently leading to the notable augmentation of active sites for the photo-degradation reaction. Aside from the above, it is worth noting that SnO2-x nanocrystals were endowed with a broad spectral response, enhancing light absorption capacity and the photo-activated carrier transfer rate with the aid of oxygen vacancy defect engineering. Accordingly, SnO2-x nanocrystals exhibited significantly enhanced photoactivity toward the degradation of the organic dye rhodamine B (RhB), which could be imputed to the synergistic effect of increasing active sites, intensified visible-light harvesting, and the separation rate of the photo-activated charge carrier caused by the oxygen vacancy defect engineering. In addition, these findings will inspire us to open up a novel pathway to design and prepare oxide compound photocatalysts modified by oxygen vacancy defects in pursuing excellent visible-light photoactivity.

5.
Nanotechnology ; 33(38)2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-35667364

RESUMO

Self-supported Cu2S/Cu(OH)2composite nanorods for highly sensitive non-enzymatic glucose sensing werein situgrown on Cu foam by simple hydrothermal treatment of aligned Cu(OH)2nanorods. The physicochemical and electrochemical properties of the as-fabricated Cu2S/Cu(OH)2composite nanorods were characterized by scanning electron microscopy, transmission electron microscopy, x-ray diffraction, Raman spectroscope, x-ray photoelectron spectroscope, cyclic voltammetry, electrochemical impedance spectroscopy, amperometrici-tmeasurements. The mechanism of the composite nanorods produced on conductive substrates was also explored. The electrode exhibits a sensitivity of 9626.88µA mM-1cm-2towards glucose with good anti-interference ability, indicating it a promising electrode material for the enhanced non-enzymatic glucose detection.


Assuntos
Técnicas Eletroquímicas , Nanotubos , Espectroscopia Dielétrica , Técnicas Eletroquímicas/métodos , Eletrodos , Glucose/química
6.
Nanotechnology ; 32(47)2021 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-34375956

RESUMO

Cu/Co-ZIF nanoflake arrays on carbon cloth are fabricated by controlling the introducing of Cu2+ions during the growth of Co-ZIF. The Cu/Co-ZIF-20 electrode prepared with 20 mM Cu2+possesses large electrochemically active surface area and bimetallic active sites, which can be revealed by cyclic voltammetry tests. The amperometrici-tmeasurements demonstrate that the Cu/Co-ZIF-20 electrode displays a wide linear range from 0.05 mM to 6.0 mM, and a high sensitivity of 1.03 mA mM-1cm-2. Good selectivity, repeatability and practical applicability indicate its promising application in enzyme-free glucose sensing.

7.
Nanotechnology ; 31(37): 375502, 2020 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-32460258

RESUMO

Herein, porous CuO spindle-like nanosheets were fabricated on a carbon cloth using a facile hydrothermal method, and surface morphology, microstructure, and glucose sensing performance were studied. The porous spindle-like nanosheets are constructed by nanoparticles and slit-like pores, exhibiting a hierarchical structure. When used for non-enzymatic glucose sensoring, the obtained CuO nanosheet electrode exhibits a wide linear range from 0.05 to 3.30 mM, a high sensitivity of 785.2 µA mM-1 cm-2 and a low detection limit of 0.22 µM (S/N = 3). Besides, good selectivity, stability, and reproducibility for glucose detection indicate a promising application of CuO nanosheet electrodes as non-enzymatic glucose sensors.


Assuntos
Técnicas Biossensoriais/métodos , Carbono/química , Cobre/química , Glucose/análise , Nanoestruturas/química , Técnicas Eletroquímicas , Eletrodos , Limite de Detecção , Porosidade , Reprodutibilidade dos Testes
8.
Nanotechnology ; 31(32): 325502, 2020 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-32325440

RESUMO

Co(OH)2 nanosheets/Cu(OH)2 nanorods composite electrodes for non-enzymatic glucose detection were fabricated by electrodepositing Co(OH)2 nanosheets on Cu(OH)2 nanorods substrate grown directly on the copper sheet via a simple one-step reaction. The Co(OH)2 nanosheets/Cu(OH)2 nanorods composite electrode was characterized by scanning electron microscopy, energy dispersive x-ray spectroscopy, x-ray diffraction and x-ray photoelectron spectroscopy. The glucose sensing performance of the composite electrode was investigated by cyclic voltammetry and chronoamperometry. The composite electrode shows high sensitivity of 2366 µA mM-1 cm-2 up to 2 mM with a lower detection limit of 0.17 mM (S/N = 3). The composite electrode is highly selective to glucose in the presence of various substances that always co-exist with glucose in real blood samples. The response of the composite towards human blood serum was in good agreement with that of commercially available glucose sensors, suggesting that a promising electrode material for highly sensitive and selective non enzymatic detection of glucose can be envisioned.

9.
RSC Adv ; 9(9): 4693-4699, 2019 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-35514671

RESUMO

In this study, bismuth molybdate/titania nanotube arrays (Bi2MoO6/TNTs) as a binder-free electrode for supercapacitors were fabricated via a facile solvothermal method. The effects of precursor amounts, solvothermal time and temperature on the microstructure and electrochemical properties of the composite were analyzed. The surface morphology, microstructure, chemical composition and chemical states of the composite electrode material were analyzed using scanning electron microscopy, X-ray diffraction, energy dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy. Cyclic voltammetry tests, galvanostatic charge-discharge measurements, and electrochemical impedance spectroscopy were employed to analyze the electrochemical behavior of the composite. A specific capacitance of ∼330 mF cm-2 has been achieved for this Bi2MoO6 nanosheets/TNTs composite electrode at the current density of 1 mA cm-2. Galvanostatic charge-discharge experiments suggest a moderate cycling stability together with 76.7% capacitance retention after 1000 cycles of continuous charge-discharge operation. These results indicate that the Bi2MoO6/TNTs composite is a promising electrode material for supercapacitors.

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