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Surg Today ; 42(12): 1154-64, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22237900

RESUMO

PURPOSE: This study evaluated a better treatment for patients with obstructive colorectal cancer (CRC) that have a poor prognosis. METHOD: This study compared the outcomes of 138 patients with obstructive CRC, including 70 primary resections, 50 resections after bowel decompression using an ileus tube, and 18 delayed resections after colostomy. RESULTS: The ileus tube and delayed resection groups included more left-sided primary lesions. The physiologic POSSUM, types 3-4, tumor size, CEA, and hospital stay of the delayed resection group were different, in comparison to both the primary resection and ileus tube groups. The histopathological type and depth of invasion of the delayed resection group included less well types and more T4 than those of the ileus tube group. The operative blood loss of the delayed resection group was more than that of the ileus tube group. There were no differences in the overall and disease-free survival among the three groups. CONCLUSION: Separately analyzing the data of the right-sided cancer group and the left-sided cancer group demonstrated that primary resection might be acceptable for right-sided obstructive CRC and delayed resection might be done for patients with poorer general conditions (high PPS) and poorer oncological prognostic factors such as more type 3/type 4 cases, a larger tumor size, a less well-differentiated histopathological type, more T4 cases, and a higher CEA level.


Assuntos
Neoplasias Colorretais/cirurgia , Descompressão Cirúrgica/métodos , Íleus/cirurgia , Cuidados Pré-Operatórios/métodos , Idoso , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Quimioterapia Adjuvante , Colectomia/métodos , Neoplasias Colorretais/complicações , Neoplasias Colorretais/tratamento farmacológico , Neoplasias Colorretais/mortalidade , Neoplasias Colorretais/patologia , Colostomia , Intervalo Livre de Doença , Feminino , Fluoruracila/administração & dosagem , Humanos , Íleus/etiologia , Tempo de Internação , Leucovorina/administração & dosagem , Metástase Linfática , Masculino , Análise Multivariada , Estadiamento de Neoplasias , Estudos Retrospectivos , Taxa de Sobrevida
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