1.
Org Lett
; 21(9): 3008-3012, 2019 05 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30888186
RESUMO
A novel chiral 1,3-diketone possessing C2 symmetry was synthesized and utilized in the asymmetric synthesis of guignardone H and I by employing sequential condensation-6π-electrocyclization reactions with the novel 1,3-diketone followed by stereoselective hydrogenation as key steps. Although the synthetic compounds differed from natural guignardone H and I, we realized that the C4-epimers of the proposed structures for guignardone H and I were the actual structures.