Synthetic Biology R&D Risks: Social-Institutional Contexts Matter!

Factors that shape actual research practices - 'social and institutional context' - typically are missing from considerations of synthetic biology R&D-related risk and containment. We argue that analyzing context is essential in identifying circumstances that create, amplify, or diminish risk, and in revealing new opportunities for avoiding or managing those risks.

Specificity and Engagement: Increasing ELSI's Relevance to Nano-Scientists.

Scholars studying the ethical, legal, and social issues (ELSI) associated with emerging technologies maintain the importance of considering these issues throughout the research and development cycle, even during the earliest stages of basic research. Embedding these considerations within the scientific process requires communication between ELSI scholars and the community of physical scientists who are conducting that basic research. We posit that this communication can be effective on a broad scale only if it links societal issues directly to characteristics of the emerging technology that are relevant to the physical and natural scientists involved in research and development. In this article, we examine nano-ELSI literature from 2003 to 2010 to discern the degree to which it makes these types of explicit connections. We find that, while the literature identifies a wide range of issues of societal concern, it generally does so in a non-specific manner. It neither links societal issues to particular forms or characteristics of widely divergent nanotechnologies nor to any of the many potential uses to which those nanotechnologies may be put. We believe that these kinds of specificity are essential to those engaged in nano-scale research. We also compare the literature-based findings to observations from interviews we conducted with nanoscientists and conclude that ELSI scholars should add technical- and application-related forms of specificity to their work and their writings to enhance effectiveness and impact in communicating with one important target audience-members of the nanoscale science community.

Planning for protective action decision making: evacuate or shelter-in-place.

Protecting the public from an airborne hazardous chemical release requires that appropriate protective actions be selected quickly. When deciding whether to recommend evacuation or shelter-in-place, decision makers must weigh the interaction of numerous factors that characterize the release, the meteorological conditions, and the populations that may be affected. This article examines the components of the protective action decision process and describes steps that should be taken in a planning context to prepare for efficient decision making during an emergency. Methods of organizing information to facilitate decision making are identified, and a model useful for detailed analysis of specific emergency scenarios is described.