[Minimally invasive method of correction of valvular insufficiency of the femoral vein in various causes of its origin genesis].

Presented herein are the results of treatment of patients with chronic venous insufficiency and trophic ulcers of lower limbs on the background of varicose disease and postthrombophlebitic syndrome. The treatment consisted in removal of pathological deep vertical venous reflux by means of a modified method of dosed narrowing of the femoral vein according to P.G. Shvalb's technique [1]. The obtained outcomes confirmed the necessity of influencing the pathological vertical deep venous reflux in patients with severe forms of chronic venous insufficiency and pronounced retrograde shunt along deep veins.

Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS).

The paper presents the results of DEFANS trial (Detralex - assessment of efficacy and safety for combined phlebectomy). The study enrolled 245 patients with varicose vein disease, who underwent unilateral combined phlebectomy. The main group (n=200) received micronized diosmin (Detralex, 1000 mg/day) for 2 weeks before and 30 days after the procedure; control group (n=45) did not receive Detralex in pre- and postoperative period. Pain severity by 10-point visual analog scale (VAS), an area of subcutaneous hemorrhage in the zone of femoral great saphenous vein resection (by original 12-point scale) and subjective feelings of limb heaviness and fatigability were evaluated 7, 14 and 30 days after the procedure. Subjective symptoms and the area of subcutaneous hemorrhage were significantly lower in the main group, then in control: 7 days after the procedure VAS score was 2.9 and 3.5, respectively; hemorrhage area - 3.4 and 4.6 points, respectively. The same trend was observed for limb heaviness and fatigability, evidencing the better exercise and orthostatic tolerance among patients of the main group in early postoperative period. Quality of life assessment by CIVIQ failed to reveal statistically significant difference between main and control groups in 4-weeks postoperative follow-up. Micronized diosmin in pre- and postoperative period after plebectomy helps to attenuate pain syndrome, to decrease postoperative haematomas and accelerate their resorption, to increase exercise tolerance in early postoperative period.

[Doppler ultrasonography in the diagnosis of occlusive diseases of blood vessels of the lower limbs]. / Ul'trazvukovaia dopplerografiia v diagnostike okkliuziruiushchikh zabolevanii sosudov nizhnikh konechnostei.

Examination of 38 healthy people and 328 patients with obliterating diseases of the lower extremity vessels by the method of ultrasonic dopplerography has been performed. Main pathological types of dopplerograms were established, methods for determination of the linear blood flow velocity are shown. Data of the examination were compared with those of angiography. High diagnostic value of the method is shown. Its use is expedient in the course of operation.