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1.
J Racial Ethn Health Disparities ; 11(2): 968-979, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36976512

RESUMO

Black women, particularly those with low-income, are projected to be the most negatively impacted group following the Supreme Court's overturn of Roe v Wade. It is expected that the rate of increase in live births, as well as the rate of maternal mortality, will be steepest for Black women due to high rates of unmet needs for contraception, unintended pregnancies, poverty, barriers to legal abortion access, and systemic racism. Previous research has shown that the legalization of abortion in 1973 significantly improved educational and employment outcomes for Black women, in particular. The current study seeks to assess the perceptions of predominantly under-resourced Black women following the overturning of Roe v Wade. Eighteen Black women participated in one of five focus groups during the summer of 2022 and shared their reactions to the Supreme Court ruling. Using grounded theory, researchers generated the following themes: sexism via forced births, economic implications, and dangers of banned abortions. Based on participants' concerns resulting from the Roe v Wade overturn, policy implications are provided for improving the following systems: safety net, child welfare, and infant and perinatal mental health care.


Assuntos
Aborto Legal , Gravidez , Criança , Feminino , Humanos , Estados Unidos
2.
J Interpers Violence ; 37(3-4): NP1253-NP1274, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-32517563

RESUMO

Women who have experienced intimate partner violence (IPV) are more likely to engage in risky sexual behaviors that increase the likelihood of adverse sexual health outcomes, including HIV acquisition. This study explored key predictors of safer sex self-efficacy in a sample of racially/ethnically diverse abused women. A total of 173 women were recruited from domestic violence agencies and completed a battery of measures that assessed risk factors associated with HIV risk. Both individual- and relationship-level predictors of safer sex self-efficacy were examined, including IPV, partner dependence, HIV knowledge, condom attitudes, self-esteem, and alcohol use. Hierarchical linear regression analysis results indicated several key predictors for safer sex self-efficacy, including IPV (B = -0.01, p < .05), partner dependence (B = -0.45, p < .001), condom attitudes (B = 0.63, p < .001), and alcohol use (B = - 0.24, p < .05). It is evident that a number of individual- and relationship-level factors affect the degree of safer sex self-efficacy among abused women. In work with this population, researchers and clinicians should intentionally attend to the identified predictors to most effectively address the needs of these women.


Assuntos
Infecções por HIV , Violência por Parceiro Íntimo , Feminino , Infecções por HIV/epidemiologia , Humanos , Fatores de Risco , Sexo Seguro , Autoeficácia , Parceiros Sexuais
3.
Food Chem Toxicol ; 46(6): 1925-32, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18321630

RESUMO

The aim of this study was to examine levels of PBDEs in breast milk associated with seafood consumptions of Taiwanese mothers. Our participants were selected from healthy women recruited between December 2000 and November 2001 from a medical center in central Taiwan. The congeners of PBDEs in 20 milk samples were analyzed by a gas chromatograph with a high resolution mass detector. The mean level of BDE47 in breast milk from mothers with pre-pregnant BMI <22.0kg/m2 had a significantly higher magnitude compared to those with pre-pregnant BMI > or = 22.0kg/m2 (1.59 vs. 0.995ng/g lipid, p=0.041). We did not find significant correlations between PBDEs exposure levels and women's age, parity, blood pressure, annual household income, and education level. Women who ate more fish and meat did not show significantly higher PBDE levels than those who ate less, but a significant difference in PBDE levels was demonstrated between the higher (2.15ng/g lipid) and lower (3.98ng/g lipid) shellfish consuming subjects (p=0.002) after an adjustment for the confounders. The ratios of PCB153/BDE47, PCB153/BDE153, and PCB153/PBDEs were significantly correlated with frequent consumption of fish and shellfish. The PCB153/BDE153 ratio was not associated with the other dietary habits (i.e. meat). The ratios of PCB153/PBDEs may therefore be a new indicator for exposure as a result of seafood consumption.


Assuntos
Comportamento Alimentar/fisiologia , Leite Humano/química , Éteres Fenílicos/análise , Bifenil Polibromatos/análise , Adulto , Fatores Etários , Pressão Sanguínea/fisiologia , Estudos de Coortes , Dioxinas/análise , Feminino , Éteres Difenil Halogenados , Humanos , Paridade , Gravidez , Alimentos Marinhos , Frutos do Mar , Fatores Socioeconômicos , Taiwan/epidemiologia
4.
Eur Respir J ; 22(5): 781-6, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14621085

RESUMO

Using questions from the International Study of Asthma and Allergies in Childhood, this study evaluated the association between undiagnosed frequent wheezing and health consequences in adolescents. The North Carolina School Asthma Survey provided self-reported questionnaire data on respiratory health from 122,829 children aged 12-14 yrs. The frequency of health consequences were compared among undiagnosed frequent wheezers, diagnosed asthmatics, and children with no wheezing symptoms or diagnosed asthma. The odds of wheezing-related sleep disturbances, limited activities, and missed school were higher among undiagnosed frequent wheezers, relative to diagnosed asthmatics. The frequency of emergency room visits and hospitalisations did not differ substantially between the undiagnosed wheezing and diagnosed asthma groups, though the undiagnosed group was less likely to have visited a physician for wheezing in the past year. Children with frequent wheezing symptoms but no asthma diagnosis experience substantial illness-related morbidity similar to that of diagnosed asthmatics. Undiagnosed frequent wheezers require more recognition from primary care physicians and need active disease management to reduce health consequences.


Assuntos
Asma/complicações , Asma/diagnóstico , Absenteísmo , Atividades Cotidianas , Adolescente , Asma/epidemiologia , Criança , Feminino , Humanos , Masculino , North Carolina/epidemiologia , Sons Respiratórios , Transtornos do Sono-Vigília/etiologia
5.
J Adolesc Health ; 29(5): 314-9, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11691592

RESUMO

PURPOSE: To describe the functional consequences of health care utilization for wheezing symptoms and diagnosed asthma in a multiracial school-based population. METHODS: Wheezing symptoms and physician-diagnosed asthma were measured in 2059 eighth graders with the International Study of Asthma and Allergies in Children video questionnaire. The sample site population was 40% African-American, 53% White, and 49% girls. Thirty-two percent of the children were on the free school lunch program. Adolescents self-reported their wheezing symptoms and physician diagnosis in response to the video wheezing scenes. They also answered questions on activity limitations, school attendance, and sleep disturbances owing to their wheezing symptoms. Multiple logistic regression was used to calculate odds ratios and adjust for potential confounders. RESULTS: Nine percent of the adolescents reported physician-diagnosed asthma with current symptoms and 27% reported current wheezing with no diagnosis of asthma. Physician-diagnosed asthmatics and wheezers were 2.6 (95% confidence interval [CI] 1.9, 3.6) and 1.8 (95% CI 1.4, 2.2) times more likely, respectively, to miss school days because of wheezing symptoms than asymptomatic adolescents. Diagnosed asthmatics were 7.8 (95% CI 5.5, 11.2) times and wheezers 4.7 (95% CI 3.5, 6.1) times more likely to have sleep disturbances than asymptomatic adolescents. Diagnosed asthmatics were 49 (95% CI 30.0, 79.8) times and wheezers 4.8 (95% CI 3.0, 7.5) times as likely to report a clinic visit for wheezing than asymptomatic adolescents. African-Americans had similar prevalence of wheezing, compared with Whites, although African-Americans were 1.4 (95% CI 1.1, 1.9) times as likely to have physician-diagnosed asthma. Girls were twice as likely to report physician-diagnosed asthma and wheezing symptoms as were boys. CONCLUSIONS: Adolescents with wheezing experienced functional consequences comparable to those of adolescents with physician-diagnosed asthma. Although wheezers may have less severe asthma than diagnosed asthmatics, the functional consequences of wheezing are likely to impair school performance and limit activity.


Assuntos
Asma/diagnóstico , Asma/etnologia , Negro ou Afro-Americano/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/etnologia , Sons Respiratórios/diagnóstico , População Branca/estatística & dados numéricos , Criança , Intervalos de Confiança , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Razão de Chances , Prevalência , Fatores de Risco , Serviços de Saúde Escolar , Fatores Socioeconômicos , Estudantes , Inquéritos e Questionários , Estados Unidos/epidemiologia , Gravação em Vídeo
6.
J Air Waste Manag Assoc ; 51(8): 1185-94, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11518292

RESUMO

This study investigated the chronic effects of emissions from three different waste incinerators on pulmonary function of both healthy and sensitive subjects with chronic respiratory symptoms. Participants were 8-80 years old, not currently smoking, and living in one of three communities each with an incinerator or one of three matched comparison communities. In total, 1018 subjects underwent a spirometric test once a year during 1992-1994. Exposure was assessed by three methods: living in an incinerator community; distance from the incinerator; and an incinerator exposure index, a function of the distance and direction of each subject's residence to the incinerator, days downwind, and average time spent outdoors. The results generally showed no statistically significant association between pulmonary function and these three incinerators, adjustment for gas oven/range use at home, length of residency, and smoking history in the mixed linear models. Two significant associations were that exposure to the hazardous waste incinerator in 1994 and to the municipal waste incinerator in 1993 were related to poor forced vital capacity. Sensitive subjects were not more adversely affected by incineration emissions than were hay fever or normal subjects. Possible explanations for the negative findings are low exposure levels and bias due to nondifferential misclassification of exposures.


Assuntos
Poluentes Atmosféricos/efeitos adversos , Incineração , Pneumopatias/etiologia , Pulmão/efeitos dos fármacos , Eliminação de Resíduos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Exposição Ambiental , Estudos Epidemiológicos , Feminino , Humanos , Exposição por Inalação , Pulmão/patologia , Masculino , Pessoa de Meia-Idade , Testes de Função Respiratória
7.
J Expo Anal Environ Epidemiol ; 11(2): 116-22, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11409004

RESUMO

This study investigates the relationship between ambient fine particle pollution and impaired cardiac autonomic control in the elderly. Heart rate variability (HRV) among 56 elderly (mean age 82) nonsmoking residents of a retirement center in Baltimore County, Maryland, was monitored for 4 weeks, from July 27 through August 22, 1998. The weather was seasonally mild (63-84 degrees F mean daily temperature) with low to moderate levels of fine particles (PM2.5 < 50 micrograms/m3). Two groups of approximately 30 subjects were examined on alternate days. A spline mixed-effects model revealed a negative relationship between outdoor 24-h average fine particulate matter (PM2.5) and high-frequency (HF) HRV that was consistent with our earlier Baltimore study for all but 2 days. These 2 days were the only days with significant precipitation in combination with elevated PM2.5. They were also unusual in that back-trajectory of their air masses was distinctly different from those on the other study days, emanating from the direction of rural Pennsylvania. Mixed-effects analysis for all 24 study days showed a small negative association of outdoor PM2.5 with HF HRV (-0.03 change in log[HF HRV] for a 10 micrograms/m3 increment in PM2.5) after adjustment for age, sex, cardiovascular status, trend, maximum temperature, average dew point temperature, random subject intercepts, and autocorrelated residuals. After excluding study days 4 and 5, this association was strengthened (-0.07 change in log[HF HRV] for 10 micrograms/m3 PM2.5, 95% CI -0.13 to -0.02) and was similar to that obtained in an earlier study (-0.12 change in log[HF HRV] for a 10 micrograms/m3 increment in outdoor PM2.5, 95% CI -0.24 to -0.00) [Liao D., Cai J., Rosamond W.D., Barnes R.W., Hutchinson R.G., Whitsel E.A., Rautaharju P., and Heiss G. Cardiac autonomic function and incident coronary heart disease: a population-based case-cohort study. The ARIC Study. Atherosclerosis Risk in Communities Study. Am J Epidemiol 1997: 145 (8): 696-706]. Acute (1 to 4 h) previous PM2.5 exposure did not have a stronger impact than the 24-h measure. A distributed lag model incorporating the six preceding 4-h means also did not indicate any effect greater than that observed in the 24-h measure. This study is consistent with earlier findings that exposures to PM2.5 are associated with decreased HRV in the elderly.


Assuntos
Poluentes Atmosféricos/efeitos adversos , Sistema Nervoso Autônomo/fisiologia , Frequência Cardíaca , Idoso , Movimentos do Ar , Feminino , Habitação para Idosos , Humanos , Masculino , Tamanho da Partícula , Estações do Ano , Temperatura
8.
J Expo Anal Environ Epidemiol ; 11(2): 97-102, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11409010

RESUMO

Lack of daily data on airborne particles has been a common problem in an air pollution research. To deal with this problem, a regression model was developed to estimate daily PM10 concentration using visibility in Bangkok from 1992 to 1997, based on 1092 visibility/PM10 pair-observations on low humidity days (humidity < or = 76.5%). Visibility was significantly and inversely associated with PM10 (r = 0.71), after adjusting for minimum temperature and winter indicator variable. The R2 of the model was 0.51.


Assuntos
Poluição do Ar/análise , Monitoramento Ambiental/estatística & dados numéricos , Modelos Teóricos , Movimentos do Ar , Poluição do Ar/estatística & dados numéricos , Monitoramento Ambiental/métodos , Previsões , Tamanho da Partícula , Análise de Regressão , Estações do Ano , Temperatura
9.
J Air Waste Manag Assoc ; 51(7): 1100-9, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15658227

RESUMO

There is an increasing trend toward using incineration to solve the problem of waste management; thus, there are concerns about the potential health impact of waste incineration. A critical review of epidemiologic studies will enhance understanding of the potential health effects of waste incineration and will provide important information regarding what needs to be investigated further. This study reviews the epidemiologic research on the potential health impact of waste incineration. Previous studies are discussed and presented according to their study population, incinerator workers or community residents, and health end points. Several studies showed significant associations between waste incineration and lower male-to-female ratio, twinning, lung cancer, laryngeal cancer, ischemic heart disease, urinary mutagens and promutagens, or blood levels of certain organic compounds and heavy metals. Other studies found no significant effects on respiratory symptoms, pulmonary function, twinning, cleft lip and palate, lung cancer, laryngeal cancer, or esophageal cancer. In conclusion, these epidemiologic studies consistently observed higher body levels of some organic chemicals and heavy metals, and no effects on respiratory symptoms or pulmonary function. The findings for cancer and reproductive outcomes were inconsistent. More hypothesis-testing epidemiologic studies are needed to investigate the potential health effects of waste incineration on incinerator workers and community residents.


Assuntos
Poluentes Atmosféricos/intoxicação , Exposição Ambiental , Incineração , Exposição Ocupacional , Saúde Pública , Meio Ambiente , Estudos Epidemiológicos , Feminino , Humanos , Masculino , Formulação de Políticas
10.
J Asthma ; 37(5): 425-34, 2000 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-10983620

RESUMO

We assessed the prevalence of diagnosed asthma, wheezing, healthcare utilization, and environmental triggers in children ages 13-14 years, and evaluated the feasibility of statewide asthma surveillance in North Carolina. A cross-sectional study (N = 1,596) was conducted using the International Survey for Asthma and Allergies in Childhood (ISAAC) questionnaire. Ten percent reported current diagnosed asthma. Nineteen percent reported wheezing symptoms with no diagnosis of asthma. Children with frequent wheezing were more likely to be poor, African-American, and female. Thirty percent of diagnosed asthmatics made 1 or more emergency room visits in the last year. Undiagnosed asthmatics were unmedicated. These results highlight the magnitude of the asthma epidemic in early adolescence, and illustrate that statewide surveillance using ISAAC is feasible.


Assuntos
Asma/epidemiologia , Adolescente , Negro ou Afro-Americano , Estudos Transversais , Feminino , Serviços de Saúde/estatística & dados numéricos , Humanos , Masculino , North Carolina/epidemiologia , Pobreza , Prevalência , Sons Respiratórios , Fatores Sexuais , Inquéritos e Questionários
11.
Ann Allergy Asthma Immunol ; 84(1): 94-100, 2000 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-10674572

RESUMO

BACKGROUND: There is little information on inhaler medication and barriers to use among a population-based sample of adolescents and whether possible variations in asthma treatment by ethnic group exist. OBJECTIVE: We describe the prevalence of inhaler use and identify barriers for proper use of asthma medication in a population-based sample of adolescents of which 34% are African-American. METHODS: A cross-sectional survey using the ISAAC (International Survey of Asthma and Allergies in Children) questionnaire was conducted in a school population-based sample (n = 2056) of 13 to 14-year-old eight grade students in the Charlotte-Mecklenburg, North Carolina public school system. Questions were asked about symptom prevalence, asthma diagnosis, inhaler use, and barriers to care. RESULTS: Fourteen percent of the children (296/2056) reported using an inhaler in the last 12 months with no differences among African-American children and white children. Twenty-six percent of inhaler users were not allowed to carry their medication on their person while at school. Girls were more likely to be allowed to carry their inhalers at school and diagnosed asthmatic girls had a higher prevalence of wheezing in the last year (47%) compared with diagnosed asthmatic boys (35%). Smoking prevalence was higher in inhaler users (26%) compared to the study population (19%). CONCLUSIONS: Inhaler use is high in this population. Adolescents using inhalers need to reduce their smoking levels. Schools need to reevaluate their policies on the use of inhalers at school.


Assuntos
Asma/tratamento farmacológico , Nebulizadores e Vaporizadores , Adolescente , População Negra , Feminino , Humanos , Masculino , Fatores Sexuais , Fumar , População Branca
12.
J Expo Anal Environ Epidemiol ; 9(4): 293-9, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10489154

RESUMO

This Six Communities Study conducted at six communities in southwestern North Carolina investigates the respiratory health status of residents whose households are located near an incinerator. This diary study makes it possible to estimate the daily variation of pulmonary function measured as peak expiratory flow rate (PEFR) related to 24-h mean PM10 levels, which were observed at each monitoring station placed in the six study communities, as a surrogate exposure measure of outdoor air pollution. Observations of PEFR among participants in each community were analyzed to determine how they varied according to the degree of exposure to ambient pollutants as well as to other cofactors including, sex, age, respiratory hypersensitivity, hours spent outdoors within the area of the selected community, and surrogate measures for indoor air pollution exposure (vacuum use and experience of air irritants at work). The findings revealed that respiratory hypersensitivity status is a predictor of declining PEFR. PM10 concentrations measured in each study area did not seem to be related to the variations of respiratory health as measured by PEFR. This study did not show any difference in respiratory health between subjects of an incinerator community and those of its comparison community. Even though this community-based study with free-living subjects shows negative findings on the relationship between respiratory health and PM10, it is worth noting that these findings must be interpreted cautiously because exposure estimation based on monitoring of ambient air likely results in misclassification of true exposure levels.


Assuntos
Poluentes Atmosféricos/efeitos adversos , Poluentes Atmosféricos/análise , Monitoramento Ambiental/métodos , Nível de Saúde , Incineração , Pico do Fluxo Expiratório , Hipersensibilidade Respiratória/diagnóstico , Hipersensibilidade Respiratória/etiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Criança , Estudos Transversais , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , North Carolina , Hipersensibilidade Respiratória/fisiopatologia , Rinite Alérgica Sazonal/diagnóstico , Rinite Alérgica Sazonal/etiologia , Rinite Alérgica Sazonal/fisiopatologia , Fatores de Risco , Fatores de Tempo
13.
Environ Health Perspect ; 107(7): 521-5, 1999 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10378998

RESUMO

examined the cardiac autonomic response to daily variations in PM in 26 elderly (mean age 81) individuals for 3 consecutive weeks. Several standardized methods were used to measure 24-hr average PM concentrations prior to the clinical test inside (indoor PM2.5) and immediately outside (outdoor PM2.5 and PM2.5-10) of participants' residences. Resting, supine, 6-min R wave to R wave (R-R) interval data were collected to estimate high frequency (0.15-0.40 Hz) and low frequency (0.04-0.15 Hz) powers and standard deviation of normal R-R intervals (SDNN) as cardiac autonomic control indices. Participant-specific lower heart rate variability days were defined as days for which the high-frequency indices fell below the first tertile of the individual's high-frequency distribution over the study period. Indoor PM2.5 > 15 microg/m3 was used to define high pollution days. Results show that the odds ratio (95% confidence interval) of low heart rate variability high frequency for high (vs. not high) pollution days was 3.08 (1.43, 6.59). The ss-coefficients (standard error) from mixed models to assess the quantitative relationship between variations in indoor PM2.5 and the log-transformed high frequency, low frequency, and SDNN were: -0.029 (0.010), -0.027 (0.009), and -0.004 (0.003), respectively. This first study of cardiac autonomic control response to daily variations of PM2.5 indicates that increased levels of PM2.5 are associated with lower cardiac autonomic control, suggesting a possible mechanistic link between PM and cardiovascular disease mortality.


Assuntos
Poluição do Ar , Sistema Nervoso Autônomo/fisiologia , Coração/inervação , Idoso , Idoso de 80 Anos ou mais , Eletrocardiografia , Feminino , Frequência Cardíaca , Humanos , Masculino
15.
Radiat Res ; 148(1): 64-80, 1997 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-9216620

RESUMO

An analysis was conducted of 27,982 deaths among 106,020 persons employed at four Federal nuclear plants in Oak Ridge, Tennessee, between 1943 and 1985. The main objectives were to extend the evaluation of the health effects of employment in the nuclear industry in Oak Ridge to include most workers who were omitted from earlier studies, to compare the mortality experience of workers among the facilities, to address methodological problems that occur when individuals employed at more than one facility are included in the analysis, and to conduct dose-response analyses for those individuals with potential exposure to external radiation. All-cause mortality and all-cancer mortality were in close agreement with national rates. The only notable excesses occurred for white males for lung cancer [standardized mortality ratio (SMR) = 1.18, 1,849 deaths] and non-malignant respiratory disease (SMR = 1.12, 1,568 deaths). A more detailed analysis revealed substantial differences in death rates among workers at the Oak Ridge plants. Evaluation of internally adjusted log SMRs using Poisson regression showed that workers employed only at Tennessee Eastman Corporation or K-25 and at multiple facilities had higher death rates than similar workers employed only at X-10 or Y-12, and that the differences were primarily due to non-cancer causes. Analysis of selected cancer causes for white males indicated large differences among the workers at the different facilities for lung cancer, leukemia and other lymphatic cancer. Dose-response analyses for external penetrating radiation were limited to a subcohort of 28,347 white males employed at X-10 or Y-12. Their collective recorded dose equivalent was 376 Sv. There was a strong "healthy worker effect" in this subcohort-all-cause SMR = 0.80 (4,786 deaths) and all-cancer SMR = 0.87 (1,134 deaths). Variables included in the analyses were age, birth cohort, a measure of socioeconomic status, length of employment, internal radiation exposure potential and facility. For external radiation dose with a 10-year lag, the excess relative risk was 0.31 per Sv (95% CI = -0.16, 1.01) for all causes and 1.45 per Sv (95% CI = 0.15, 3.48) for all cancer. The estimated excess relative risk for leukemia was negative but imprecisely determined. A preliminary dose adjustment procedure was developed to compensate for missing dose but not other dosimetry errors. Results of the analyses using the adjusted doses suggest that the effect of missing dose is an upward bias in dose-response coefficients and test statistics.


Assuntos
Neoplasias/mortalidade , Doenças Profissionais , Exposição Ocupacional , Relação Dose-Resposta à Radiação , Feminino , Órgãos Governamentais , Humanos , Masculino , Risco , Tennessee , Fatores de Tempo
16.
Zhonghua Yi Xue Za Zhi (Taipei) ; 59(3): 210-5, 1997 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-9198299

RESUMO

This report concerns a patient suffering from a severe neck pain on the third day after a traffic accident. This condition was followed by a lateral medullary infarction on the next day. One week later, he was transferred to this hospital and dissection of the vertebral artery was disclosed. It should be emphasized that in case of acute cervical spine injury or severe neck pain after a major trauma, vertebral artery dissection should be considered, as its early diagnosis may have crucial therapeutic implications. In addition, the advantages of the combination of magnetic resonance imaging and magnetic resonance angiography as diagnostic tools-of-choice are emphasized.


Assuntos
Artéria Vertebral/lesões , Ferimentos não Penetrantes , Acidentes de Trânsito , Adulto , Hemorragia Cerebral/diagnóstico , Infarto Cerebral/diagnóstico , Hematoma/diagnóstico , Humanos , Síndrome Medular Lateral/diagnóstico , Angiografia por Ressonância Magnética , Imageamento por Ressonância Magnética , Masculino , Cervicalgia/etiologia
17.
Am J Epidemiol ; 145(6): 479-84; discussion 485-7, 1997 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-9063337

RESUMO

Academic epidemiology has failed to develop the scientific methods and the knowledge base to support the fundamental public health mission of preventing disease and promoting health through organized community efforts. As a basic science of public health, epidemiology should attempt to understand health and disease from a community and ecologic perspective as a consequence of how society is organized and behaves, what impact social and economic forces have on disease incidence rates, and what community actions will be effective in altering incidence rates. However, as taught in most textbooks and as widely practiced by academicians, epidemiology has become a biomedical discipline focused on the distribution and determinants of disease in groups of individuals who happen to have some common characteristics, exposures, or diseases. The ecology of human health has not been addressed, and the societal context in which disease occurs has been either disregarded or deliberately abstracted from consideration. By essentially assuming that risk factors for disease in individuals can be summed to understand the causes of disease in populations, academic epidemiology has limited itself to a narrow biomedical perspective, thereby committing the bio-medical fallacy of inferring that disease in populations can be understood by studying risk factors for disease in individuals. Epidemiology should be redefined as a study of the distribution and societal determinants of the health status of populations. This definition provides a stronger link to be the primary mission of public health and places an appropriate emphasis on the social, economic, environmental, and cultural determinants of population health. Epidemiology must cross the boundaries of other population sciences and add to its scope a macro-epidemiology, a study of causes from a truly population perspective, considering health and disease within the context of the total human environment.


Assuntos
Epidemiologia , Saúde Pública , Indicadores Básicos de Saúde , Humanos , Medicina Preventiva , Projetos de Pesquisa
18.
Am J Epidemiol ; 145(3): 258-68, 1997 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-9012599

RESUMO

To investigate acute, irreversible effects of exposure to ozone and other air pollutants, the authors examined daily death counts in relation to air pollution levels in Mexico City during 1990-1992. When considered singly in Poisson regression models accounting for periodic effects, the rate ratio for total mortality associated with a 100-ppb increment in 1-hour maximum ozone concentration was 1.024 (95% confidence interval (CI) 1.011-1.039). Measures of average ozone concentration were somewhat more strongly related to mortality. The rate ratio was 1.024 (95% CI 0.984-1.062) per 100 ppb for sulfur dioxide and 1.050 (95% CI 1.030-1.067) per 100 micrograms/m3 for total suspended particulates. However, when all three pollutants were considered simultaneously, only total suspended particulates remained associated with mortality, indicating excess mortality of 6% per 100 micrograms/m3 (rate ratio = 1.058, 95% CI 1.033-1.083), consistent with observations in other cities in the United States and Europe. The authors found no independent effect of ozone, but it is difficult to attribute observed effects to a single pollutant in light of the complexity and variability of the mixture to which people are exposed. Nevertheless, particulate matter may be a useful indicator of the risk associated with ambient air pollution.


Assuntos
Poluentes Atmosféricos/análise , Mortalidade , Ozônio/análise , Saúde da População Urbana , Adolescente , Adulto , Idoso , Poluentes Atmosféricos/efeitos adversos , Criança , Pré-Escolar , Intervalos de Confiança , Atestado de Óbito , Monitoramento Ambiental , Monitoramento Epidemiológico , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Ozônio/efeitos adversos , Análise de Regressão , Fatores de Risco , Tempo (Meteorologia)
20.
Res Rep Health Eff Inst ; (75): 1-37; discussion 39-45, 1996 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-8916289

RESUMO

Daily death counts in Mexico City were examined in relation to ambient ozone levels during 1990-1992 for the purpose of investigating the acute, irreversible effects of air pollution, with emphasis on ozone exposure. Air pollution data were obtained from nine monitoring stations operated by the Departamento del Distrito Federal. Mortality data were provided by the Instituto Nacional de Estadística, Geografía, e Informática. Increases in numbers of deaths were positively associated with elevated air pollution levels on the same day and on the previous day. The magnitude of the increases was small but statistically significant, after Poisson regression models were used to adjust for temperature and long-term trends. In models using data for a single pollutant, the "crude" ratio for total mortality associated with an increase of 100 parts per billion (ppb)* in one-hour maximum ozone concentration was 1.029 (95% CI 1.015, 1.044). A moving average of ozone showed a stronger association (rate ratio [RR] = 1.048, 95% CI 1.025, 1.070), and excess mortality (an increase in the number of deaths, relative to the average on days with low pollution levels) was more evident for persons over 65 years of age. Separate analyses of the effect of elevated ozone for different areas of the city showed similar results, but they were not statistically significant. Other pollutants also were related to mortality. The RR was 1.075 (95% CI 0.984, 1.062) per 100-ppb increase for sulfur dioxide and 1.049 (95% CI 1.030, 1.067) per 100 micrograms/m3 increase in total suspended particulates (TSP) when these pollutants were considered in separate models. However, when all three pollutants were considered simultaneously, only TSP remained associated with mortality, indicating excess mortality of 5% per 100 micrograms/m3 increase [RR = 1.052, 95% CI 1.034, 1.072]. The excess mortality associated with TSP is consistent with that observed in other cities in America and Europe. This study provides some evidence that ozone is associated with all-cause mortality and with mortality among the elderly after controlling for long-term cycles. However, ozone levels exhibited little or no effect on mortality rates when other air pollutants were considered simultaneously. Particulate matter appeared to be an important pollutant; it independently predicted changes in mortality. Nevertheless, because of the complexity and variability of the mixtures to which people are exposed, it is difficult to attribute the observed effects to a single pollutant. The technical feasibility and scientific validity of isolating the effect of single pollutants in such complex mixtures requires further research and careful consideration. Given the large population living in and exposed to ambient air pollution in Mexico City and other metropolises throughout the world, these small but significant associations of mortality with air pollution indices are of public health concern.


Assuntos
Poluentes Atmosféricos/efeitos adversos , Mortalidade , Ozônio/efeitos adversos , Saúde da População Urbana , Adolescente , Adulto , Distribuição por Idade , Idoso , Poluentes Atmosféricos/análise , Criança , Pré-Escolar , Monitoramento Ambiental , Monitoramento Epidemiológico , Humanos , Lactente , Estudos Longitudinais , México/epidemiologia , Pessoa de Meia-Idade , Mortalidade/tendências , Ozônio/análise , Análise de Regressão , Dióxido de Enxofre/efeitos adversos , Dióxido de Enxofre/análise
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