Association of Food Consumption According to the Degree of Processing and Sociodemographic Conditions in Older Adults.

Several factors can impact food consumption in older adults, including those of sociodemographic, physiological, and chronic non-communicable diseases. This study aimed to evaluate the association of food consumption according to its degree of processing with sociodemographic conditions in community-dwelling older adults. Food intake was evaluated from 24-h recall data. All food items were classified according to the degree of processing into four groups as follows: in natura or minimally processed, culinary ingredients, processed, and ultra-processed foods. Food groups were considered dependent variables in a quantile regression model, adjusting for sex, age, schooling, ethnicity, and number of residents. Women and individuals with higher levels of education had lower consumption of in natura or minimally processed foods and higher consumption of ultra-processed foods. The yellow or indigenous ethnicity presented the lowest consumption of processed foods; older people who lived with three or more individuals had the highest consumption of culinary ingredients, whereas the older people who lived with one to two people had the highest consumption of processed foods and the lowest consumption of ultra-processed. These groups may be the target of educational and public policies to improve diet quality and contribute to quality of life in older ages.

A experiência da COVID-19 pelo olhar de quem apresentou a doença: um estudo qualitativo / The experience of COVID-19 through the eyes of those who presented the disease: a qualitative study

Conhecer e compreender, por meio do olhar da pessoa que apresentou a COVID-19, como foi ter passado por essa experiência. Pesquisa descritiva exploratória qualitativa. População do estudo composta por indivíduos com diagnóstico de COVID-19encaminhados para tratamento em um centro de reabilitação física. Coleta de dados realizada por meio de um questionário (caracterização) e entrevista semiestruturada. As respostas da entrevista foram analisadas com a Análise do Conteúdo (Bardin).Os participantes relataram uma experiência ruim e difícil, com uma doença desconhecida. Diversos sentimentos foram vivenciados, sendo o medo muito enfatizado. Os entrevistados apresentaram limitações físicas, emocionais e perda da independência. Passaram a se preocupar mais com sua saúde e valorizar mais a família, amigos e profissionais da saúde. É importante a assistência precoce a essa população, disponibilizando meios de informações sobre a doença, atendimento psicoterapêutico e de reabilitação, prevenindo efeitos a longo prazo, que dificultam sua recuperação.

To know and understand, through the eyes of the person who had COVID-19, what it was like to have gone through this experience. Qualitative exploratory descriptive research. Study population composed of individuals diagnosed with COVID-19referred for treatment at a Physical Rehabilitation Center. Data collection performed through a questionnaire (characterization) and semi-structured interview. The interview responses were analyzed using Content Analysis (Bardin). Participants reported a bad and difficult experience with an unknown illness. Several feelings were experienced, fear being very emphasized. Respondents had physical and emotional limitations and loss of independence. They started to worry more about their health and value family, friends, and health professionals. Early assistance to this population is important, providing means of information about the disease, psychotherapeutic and rehabilitation care, preventing long-term effects that hinder their recovery

Factors associated with added sugar consumption of older adults from the region of Campinas-SP, Brazil. / Fatores associados ao consumo de açúcares de adição de idosos da região de Campinas-SP, Brasil.

Adequate nutrition has a profound impact on older adults' health. Therefore, special attention should be given to the dietetic intake of added sugars, which in excess is associated with poorer control of chronic diseases in this phase. The aim of the study was to evaluate the prevalence of consumption of added sugars in older adults in the Campinas-SP region, its associated factors, and its main dietary sources. A cross-sectional study was conducted in the region of Campinas-SP, with a convenience sample of 586 older individuals. Intake was obtained using two 24-hour food recalls, and values >5% of total energy consumption were considered inadequate. The contribution of the groups and foods in relation to the total content of sugars was also calculated. A critical level of p<0.05 was considered. The average intake of added sugars was higher than recommended (7.0%), and this inadequacy was observed in more than half of the sample, being table sugar and honey the main dietary sources. The prevalence of inadequate consumption was higher among women (69.8%; p=0.004) and individuals with low weight (83.7%; p=0.014), and lower in those with diabetes (47.8%; p<0.001). Results indicate that health and nutrition actions should be developed to ensure adequate sugar intake at this stage.

A alimentação adequada tem profundo impacto na saúde dos idosos, e uma especial atenção deve ser dada ao consumo de açúcares de adição na dieta, que em excesso está associado a pior controle das doenças crônicas nesta fase. O objetivo do estudo foi avaliar a prevalência do consumo de açúcares de adição de idosos da região de Campinas-SP, seus fatores associados e suas principais fontes alimentares. Trata-se de estudo transversal realizado na região de Campinas-SP, com amostra de conveniência de 586 idosos. O consumo foi obtido por meio de dois recordatórios de 24 horas, sendo inadequado se >5% do consumo energético total. Também foi calculada a contribuição dos alimentos em relação ao teor total de açúcares. Considerou-se nível crítico de p<0,05. O consumo médio de açúcares de adição estava acima do recomendado (7,0%), inadequado em mais da metade da população estudada, sendo o açúcar de mesa e o mel as principais fontes dietéticas. A prevalência de inadequação do consumo foi maior entre mulheres (69,8%; p=0,004) e em indivíduos com baixo peso (83,7%; p=0,014), e o consumo foi menor em portadores de diabetes (47,8%; p<0,001). Os resultados apontam para que sejam elaboradas ações de saúde e nutrição a fim de garantir um consumo adequado de açúcares nesta fase.

Fatores associados ao consumo de açúcares de adição de idosos da região de Campinas-SP, Brasil / Factors associated with added sugar consumption of older adults from the region of Campinas-SP, Brazil

Resumo A alimentação adequada tem profundo impacto na saúde dos idosos, e uma especial atenção deve ser dada ao consumo de açúcares de adição na dieta, que em excesso está associado a pior controle das doenças crônicas nesta fase. O objetivo do estudo foi avaliar a prevalência do consumo de açúcares de adição de idosos da região de Campinas-SP, seus fatores associados e suas principais fontes alimentares. Trata-se de estudo transversal realizado na região de Campinas-SP, com amostra de conveniência de 586 idosos. O consumo foi obtido por meio de dois recordatórios de 24 horas, sendo inadequado se >5% do consumo energético total. Também foi calculada a contribuição dos alimentos em relação ao teor total de açúcares. Considerou-se nível crítico de p<0,05. O consumo médio de açúcares de adição estava acima do recomendado (7,0%), inadequado em mais da metade da população estudada, sendo o açúcar de mesa e o mel as principais fontes dietéticas. A prevalência de inadequação do consumo foi maior entre mulheres (69,8%; p=0,004) e em indivíduos com baixo peso (83,7%; p=0,014), e o consumo foi menor em portadores de diabetes (47,8%; p<0,001). Os resultados apontam para que sejam elaboradas ações de saúde e nutrição a fim de garantir um consumo adequado de açúcares nesta fase.

Abstract Adequate nutrition has a profound impact on older adults' health. Therefore, special attention should be given to the dietetic intake of added sugars, which in excess is associated with poorer control of chronic diseases in this phase. The aim of the study was to evaluate the prevalence of consumption of added sugars in older adults in the Campinas-SP region, its associated factors, and its main dietary sources. A cross-sectional study was conducted in the region of Campinas-SP, with a convenience sample of 586 older individuals. Intake was obtained using two 24-hour food recalls, and values >5% of total energy consumption were considered inadequate. The contribution of the groups and foods in relation to the total content of sugars was also calculated. A critical level of p<0.05 was considered. The average intake of added sugars was higher than recommended (7.0%), and this inadequacy was observed in more than half of the sample, being table sugar and honey the main dietary sources. The prevalence of inadequate consumption was higher among women (69.8%; p=0.004) and individuals with low weight (83.7%; p=0.014), and lower in those with diabetes (47.8%; p<0.001). Results indicate that health and nutrition actions should be developed to ensure adequate sugar intake at this stage.

Supplementation with okra combined or not with exercise training is able to protect the heart of animals with metabolic syndrome.

The metabolic syndrome (MetS) is a clinical manifestation strongly associated with cardiovascular disease, the main cause of death worldwide. In view of this scenario, many therapeutic proposals have appeared in order to optimize the treatment of individuals with MetS, including the practice of exercise training (ET) and the consumption of okra (O). The aim of the present study was to evaluate the effect of O consumption and/or ET in animals with MetS. In all, 32 male Zucker rats (fa/fa) at 10 weeks old were randomly distributed into four groups of 8 animals each: MetS, MetS+O, MetS+ET and MetS+ET+O, and 8 lean Zucker rats (fa/ +) comprised the control group. Okra was administered by orogastric gavage 2x/day (morning and night, 100 mg/kg), 5 days/week, for 6 weeks. The ET was performed on a treadmill 1x/day (afternoon), 5 days/week, 60 min/day, in an intensity of 70% of maximal capacity, for the same days of O treatment. It was found that, O consumption alone was able to promote improved insulin sensitivity (MetS 93.93 ± 8.54 mg/dL vs. MetS+O 69.95 ± 18.7 mg/dL, p ≤ 0.05, d = 1.65, CI = 50.32 -89.58, triglyceride reduction (MetS 492.9 ± 97.8 mg/dL vs. MetS+O 334.9 ± 98.0 mg/dL, p ≤ 0.05, d = 1.61, CI = 193.2-398.7). In addition, it promoted a reduction in systolic blood pressure (MetS 149.0 ± 9.3 mmHg vs. MetS+O 132.0 ± 11.4 mmHg, p ≤ 0.05, d = 1.63, CI = 120-140), prevented an increase in cardiac collagen (MetS 12.60 ± 2.08% vs. MetS+O 7.52 ± 0.77%, p ≤ 0.05, d = 3.24, CI = 6.56-8.49). When associated with ET, the results were similar. Thus, we conclude that O consumption combined or not with aerobic ET can have a protective effect on the cardiac tissue of rats with MetS.

Association between zinc deficiency and cognitive decline in community-dwelling older adults. / Associação entre deficiência de zinco e declínio cognitivo em idosos da comunidade.

This is a cross-sectional study evaluating the association between zinc deficiency and cognitive decline in 591 community-dwelling older adults living in the cities of Campinas, Limeira, and Piracicaba-SP. Cognitive status was evaluated using the Cognitive Abilities Screening Instrument-CASI-S, considering a decline for scores <23 for those aged 60-69 and <20 for those aged ≥70 years. Among the evaluated cognitive domains, older adults with zinc deficiency had significantly lower mean scores on the memory test (p=0.018). For zinc deficiency, values below 70 µg/dL were considered for women and 74 µg/dL for men. The prevalence of zinc deficiency was 3.9%, and cognitive deficit was 9.4%, being significantly higher in those with zinc deficiency compared with those with normal serum zinc concentrations. In adjusted multiple logistic regression analysis, the factors that remained associated with cognitive decline were zinc deficiency (OR=3.80; 95%CI=1.30-11.12), low schooling level (OR=3.12; 95%CI=1.49-6.50), lack of a partner (OR=1.88; 95%CI=1.04-3.42), risk of malnutrition (OR=3.98; 95%CI=2.36-6.71), and a history of encephalic vascular accident (OR=2.70; 95%CI=1.04-6.98). Zinc deficiency was associated with the presence of cognitive decline in older adults. Actions in primary health care are necessary to prevent the deficiency of this nutrient.

Estudo transversal avaliou a associação entre deficiência de zinco sérico e declínio cognitivo em 591 idosos da comunidade residentes nos municípios de Campinas, Limeira e Piracicaba-SP. A cognição foi avaliada pelo Instrumento de Triagem de Habilidades Cognitivas-CASI-S considerando declínio pontuação <23 em idosos de 60-69 anos e <20 em idosos ≥70 anos. Considerou-se deficiência de zinco sérico valor de <70 µg/dL para mulheres e 74 µg/dL para homens. Entre os domínios cognitivos, idosos com deficiência de zinco tiveram pontuação média significativamente menor no teste de memória (p=0,018). A prevalência da deficiência de zinco foi de 3,9%, e de 9,4% de declínio cognitivo, sendo significativamente maior em idosos com deficiência de zinco do que os que não tinham (26,1% e 8,8%, respectivamente). Em análise de regressão logística múltipla ajustada, os fatores que permaneceram associados ao declínio cognitivo foram deficiência de zinco (OR=3,80; IC95%=1,30-11,12), baixa escolaridade (OR=3,12; IC95%=1,49-6,50), não ter companheiro (OR=1,88; IC95%=1,04-3,42), risco de desnutrição (OR=3,98; IC95%=2,36-6,71), e histórico de acidente vascular encefálico (OR=2,70; IC95%=1,04-6,98). A deficiência de zinco foi associada ao declínio cognitivo em idosos. Ações na atenção básica de saúde são necessárias para prevenir a deficiência deste nutriente.

Vitamin D insufficiency and factors associated: a study with older adults people from primary health care network. / Insuficiência de vitamina D e fatores associados: um estudo com idosos assistidos por serviços de atenção básica à saúde.

This article aims to analyze vitamin D insufficiency and factors associated among older adults using primary health care services. This is a cross-sectional study that evaluated 533 older adults individuals (≥ 60 years old) in three cities in the state of São Paulo, Brazil. Serum level of 25-hydroxyvitamin D (25-OHD) was evaluated by chemiluminescence. The factors evaluated were sociodemographic information (sex, age group, ethnicity, education, income, marital status), health conditions (reported diseases), body composition (BMI, waist circumference), lifestyle (physical activity and smoking), and sun exposure (purpose, duration, frequency, time of exposure, exposed body parts, use of sunscreen, skin type). The prevalence of vitamin D insufficiency was 64.5%, presenting association with female participants, non-white/unreported ethnicity, low weight, high waist circumference (risk for CVD - cardiovascular disease), and physical inactivity. Negative association was observed with habitual sun exposure of hands, arms and legs, during leisure activities, daily commuting and physical activity, and between 9 am and 3 pm. The findings show the relevance of factors such as sex, ethnicity, body composition, physical activity, and sun exposure habits in the high prevalence of inadequate levels of vitamin D among older adults.

O objetivo deste artigo é analisar a insuficiência de vitamina D e fatores associados em idosos assistidos na atenção primária à saúde. Trata-se de um estudo transversal que avaliou 533 idosos (≥ 60 anos) em três cidades do estado de São Paulo, Brasil. Foi avaliada a 25-hidroxivitamina D (25 OH D) sérica por quimioluminescência. Os fatores avaliados foram condições sociodemográficas (sexo, faixa etária, etnia, escolaridade, renda, estado civil), de saúde (doenças referidas), composição corporal (IMC, circunferência da cintura), estilo de vida (atividade física e tabagismo) e exposição solar (finalidade, duração, frequência e horário de exposição, partes expostas, uso de protetor solar, tipo de pele). A prevalência de insuficiência foi de 64,5%, com associação para sexo feminino, etnia não brancos/não declarados, baixo peso, circunferência da cintura elevada (risco para DCV) e inatividade física. Houve associação negativa para exposição solar habitual de mãos, braços e pernas, durante atividade de lazer, deslocamentos diários e atividade física e entre as 9h e 15h. Os achados mostram a relevância de fatores como sexo, etnia, composição corporal, atividade física e hábitos de exposição solar na alta prevalência de níveis inadequados de vitamina D em idosos.

Cryotherapy Produces Pain Relief in Young People with Primary Dysmenorrhea.

Primary dysmenorrhea is characterized as painful menstruation without associated pelvic disease and has been considered common among young people of reproductive age. Cryotherapy is a technique aimed at analgesia and anti-inflammatory action. The objective of this study was to analyze the analgesic efficacy of cryotherapy in sedentary youth with primary dysmenorrhea. Methods were included sedentary, affected by primary dysmenorrhea. The analysis of pain intensity by visual analog scale (VAS) and the Brazilian Version of the Wisconsin Brief Pain Questionnaire were used for evaluation. The participants were randomly separated into a control group (CG, n = 10) and a cryotherapy group (CryoG, n = 10). The evaluations and treatment occurred during a menstrual cycle, with three interventions, in the initial 3 days of higher menstrual flow history report. CG showed a reduction in pain when comparing the 1st with the 4th day of assessment; CryoG showed a daily reduction in VAS; for the pain questionnaire, cryotherapy showed a reduction in interference with sleep dysmenorrhea; and for all other variables, although there was no significant difference, a large effect size was observed. Cryotherapy was effective in reducing pain in women with primary dysmenorrhea, with indication of clinical improvement in daily living activities.

Insuficiência de vitamina D e fatores associados: um estudo com idosos assistidos por serviços de atenção básica à saúde / Vitamin D insufficiency and factors associated: a study with older adults people from primary health care network

Resumo O objetivo deste artigo é analisar a insuficiência de vitamina D e fatores associados em idosos assistidos na atenção primária à saúde. Trata-se de um estudo transversal que avaliou 533 idosos (≥ 60 anos) em três cidades do estado de São Paulo, Brasil. Foi avaliada a 25-hidroxivitamina D (25 OH D) sérica por quimioluminescência. Os fatores avaliados foram condições sociodemográficas (sexo, faixa etária, etnia, escolaridade, renda, estado civil), de saúde (doenças referidas), composição corporal (IMC, circunferência da cintura), estilo de vida (atividade física e tabagismo) e exposição solar (finalidade, duração, frequência e horário de exposição, partes expostas, uso de protetor solar, tipo de pele). A prevalência de insuficiência foi de 64,5%, com associação para sexo feminino, etnia não brancos/não declarados, baixo peso, circunferência da cintura elevada (risco para DCV) e inatividade física. Houve associação negativa para exposição solar habitual de mãos, braços e pernas, durante atividade de lazer, deslocamentos diários e atividade física e entre as 9h e 15h. Os achados mostram a relevância de fatores como sexo, etnia, composição corporal, atividade física e hábitos de exposição solar na alta prevalência de níveis inadequados de vitamina D em idosos.

Abstract This article aims to analyze vitamin D insufficiency and factors associated among older adults using primary health care services. This is a cross-sectional study that evaluated 533 older adults individuals (≥ 60 years old) in three cities in the state of São Paulo, Brazil. Serum level of 25-hydroxyvitamin D (25-OHD) was evaluated by chemiluminescence. The factors evaluated were sociodemographic information (sex, age group, ethnicity, education, income, marital status), health conditions (reported diseases), body composition (BMI, waist circumference), lifestyle (physical activity and smoking), and sun exposure (purpose, duration, frequency, time of exposure, exposed body parts, use of sunscreen, skin type). The prevalence of vitamin D insufficiency was 64.5%, presenting association with female participants, non-white/unreported ethnicity, low weight, high waist circumference (risk for CVD - cardiovascular disease), and physical inactivity. Negative association was observed with habitual sun exposure of hands, arms and legs, during leisure activities, daily commuting and physical activity, and between 9 am and 3 pm. The findings show the relevance of factors such as sex, ethnicity, body composition, physical activity, and sun exposure habits in the high prevalence of inadequate levels of vitamin D among older adults.

Associação entre deficiência de zinco e declínio cognitivo em idosos da comunidade / Association between zinc deficiency and cognitive decline in community-dwelling older adults

Resumo Estudo transversal avaliou a associação entre deficiência de zinco sérico e declínio cognitivo em 591 idosos da comunidade residentes nos municípios de Campinas, Limeira e Piracicaba-SP. A cognição foi avaliada pelo Instrumento de Triagem de Habilidades Cognitivas-CASI-S considerando declínio pontuação <23 em idosos de 60-69 anos e <20 em idosos ≥70 anos. Considerou-se deficiência de zinco sérico valor de <70 µg/dL para mulheres e 74 µg/dL para homens. Entre os domínios cognitivos, idosos com deficiência de zinco tiveram pontuação média significativamente menor no teste de memória (p=0,018). A prevalência da deficiência de zinco foi de 3,9%, e de 9,4% de declínio cognitivo, sendo significativamente maior em idosos com deficiência de zinco do que os que não tinham (26,1% e 8,8%, respectivamente). Em análise de regressão logística múltipla ajustada, os fatores que permaneceram associados ao declínio cognitivo foram deficiência de zinco (OR=3,80; IC95%=1,30-11,12), baixa escolaridade (OR=3,12; IC95%=1,49-6,50), não ter companheiro (OR=1,88; IC95%=1,04-3,42), risco de desnutrição (OR=3,98; IC95%=2,36-6,71), e histórico de acidente vascular encefálico (OR=2,70; IC95%=1,04-6,98). A deficiência de zinco foi associada ao declínio cognitivo em idosos. Ações na atenção básica de saúde são necessárias para prevenir a deficiência deste nutriente.

Abstract This is a cross-sectional study evaluating the association between zinc deficiency and cognitive decline in 591 community-dwelling older adults living in the cities of Campinas, Limeira, and Piracicaba-SP. Cognitive status was evaluated using the Cognitive Abilities Screening Instrument-CASI-S, considering a decline for scores <23 for those aged 60-69 and <20 for those aged ≥70 years. Among the evaluated cognitive domains, older adults with zinc deficiency had significantly lower mean scores on the memory test (p=0.018). For zinc deficiency, values below 70 µg/dL were considered for women and 74 µg/dL for men. The prevalence of zinc deficiency was 3.9%, and cognitive deficit was 9.4%, being significantly higher in those with zinc deficiency compared with those with normal serum zinc concentrations. In adjusted multiple logistic regression analysis, the factors that remained associated with cognitive decline were zinc deficiency (OR=3.80; 95%CI=1.30-11.12), low schooling level (OR=3.12; 95%CI=1.49-6.50), lack of a partner (OR=1.88; 95%CI=1.04-3.42), risk of malnutrition (OR=3.98; 95%CI=2.36-6.71), and a history of encephalic vascular accident (OR=2.70; 95%CI=1.04-6.98). Zinc deficiency was associated with the presence of cognitive decline in older adults. Actions in primary health care are necessary to prevent the deficiency of this nutrient.

[Low intake of dietary fibers among the elderly: 2014/2015 ISACAMP population-based study]. / Baixa ingestão de fibras alimentares em idosos: estudo de base populacional ISACAMP 2014/2015.

The scope of this article is to evaluate the prevalence of inadequate dietary fiber intake and associated factors among elderly adults. A cross-sectional population-based study evaluating participants from the Health Survey of the City of Campinas (ISACAMP) was conducted in 2014/2015, with 1,074 elderly individuals (≥60 years). Dietary fiber intake was obtained using a 24-hour recall, and the prevalence of inadequate fibers was estimated according to the cut-off point of the Institute of Medicine (30 g/day for men and 21 g/day for women). The factors evaluated were sociodemographic conditions (sex, age, schooling, income, marital status), health (number of reported diseases) and lifestyle (physical activity, smoking and alcohol consumption). The prevalence of inadequate dietary fiber intake was 86.6%, being higher in men (RP=1.10), single or divorced (RP=1.09) and physically inactive (PR=1.07). Elderly adults with higher incomes and who reported having 1 to 2 chronic non-communicable diseases had a higher intake of fibers. The high prevalence of inadequate dietary fiber intake in the elderly adults indicates that health and nutrition actions should be developed to ensure adequate dietary intake of these compounds.

O objetivo deste artigo é avaliar a prevalência de inadequação do consumo de fibras alimentares e seus fatores associados em idosos. Estudo transversal de base populacional que avaliou participantes do Inquérito de Saúde do Município de Campinas (ISACAMP) em 2014/2015, com 1.074 idosos (≥60 anos). O consumo de fibras na dieta foi obtido utilizando um recordatório de 24h, e foi estimada a prevalência de inadequação de fibras de acordo com o ponto de corte do Institute of Medicine (30 g/dia para homens e 21 g/dia para mulheres). Os fatores avaliados foram condições sociodemográficas (sexo, idade, escolaridade, renda, estado conjugal), de saúde (número de doenças referidas) e estilo de vida (atividade física, tabagismo e etilismo). A prevalência de inadequação do consumo de fibras alimentares foi de 86,6%, sendo maior em homens (RP=1,10), em solteiros ou divorciados (RP=1,09) e inativos fisicamente (RP=1,07). Idosos de maior renda e que relataram ter de 1 a 2 doenças crônicas não transmissíveis tiveram maior ingestão de fibras. A alta prevalência da inadequação do consumo de fibras alimentares em idosos aponta para que sejam desenvolvidas ações de saúde e nutrição a fim de garantir um consumo alimentar adequado destes compostos.

Antimicrobial dressing of silver sulfadiazine-loaded halloysite/cassava starch-based (bio)nanocomposites.

(Bio)nanocomposites have been studied for biomedical applications, including the treatment of wounds. However, wound infection is one of the main problems of wound care management, and the use of wound dressings with antibacterial agents is essential. This work focused on developing and characterizing silver sulfadiazine-loaded halloysite/cassava starch-based (bio)nanocomposites potentially suitable as antimicrobial dressing. Silver sulfadiazine was complexed inside the halloysite nanotubes lumen, and the drug-loaded nanotubes were incorporated in thermoplastic starch dispersion, forming the (bio)nanocomposites. The silver sulfadiazine-loaded halloysite and the (bio)nanocomposite were characterized by zeta potential, scanning electron microscopy, X-ray diffraction, and infrared spectroscopy. The dressing properties of (bio)nanocomposites (water vapor permeability and mechanical stability) and their antimicrobial efficacy by Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus were also evaluated. Physicochemical studies suggested the silver sulfadiazine-loaded halloysite complexation (zeta potential of -38.9 mV) and its interactions with the starch forming the nanocomposites. The silver sulfadiazine-loaded halloysite/starch-based (bio)nanocomposites possessed a homogeneous and organized structure. Also, they had mechanical properties to be used as a dressing (13.73 ± 3.09 MPa and 3.17 ± 1.28% of elongation at break), and its permeability (6.18 ± 0.43 (10-13) g.Pa-1.s-1.m-1) could be able to maintain the environmental moisture at the wound surface. Besides that, the (bio)nanocomposites acted against the studied bacteria, being a potential contact antimicrobial and biodegradable wound dressing. Finally, the developed (bio)nanocomposites are semi-occlusive and good candidates for dry wounds to be widely in vitro and in vivo tested as controlled silver sulfadiazine delivery dressing.

Impact of captive conditions on female germinal epithelium of the butterflyfish Chaetodon striatus (Perciformes: Chaetodontidae).

Chaetodon striatus is a cosmopolitan seawater species present in aquaria all over the world and its extractivism is quite high. The lack of studies on the reproductive biology of C. striatus contributes to the difficulty in managing the species outside its natural habitat. Without knowledge of the mechanisms that control or affect gonadal changes, reproduction of C. striatus in captivity has become almost impossible, considering that the species is quite sensitive and the effect of captive conditions on its reproductive biology is unknown. Therefore, this study aimed to evaluate the effect on its reproductive biology of the animal's confinement and possible alteration in structure of the ovaries. In C. striatus, after oocyte development, for animals confined in small spaces, maturing oocytes undergo atresia. During atresia, ovarian follicles were at different stages of degeneration, characterized by the progressive loss of the basement membrane and disorganization of the follicle complex. In the advanced stage of follicular atresia, there was total loss of the basement membrane, culminating in degradation of the follicle complex. In unconfined animals, oocyte development and maturation were not affected. Confinement also affected the cell structure of the germinal epithelium, which showed large numbers of apoptotic bodies. The difference in cortisol and glucose levels between the unconfined and confined groups was significant, which may have to do with the change found in the ovaries, such as extensive follicular atresia and loss of the basement membrane.

High prevalence of inadequate dietary fiber consumption and associated factors in older adults: a population-based study. / Elevada prevalência de inadequação do consumo de fibras alimentares em idosos e fatores associados: um estudo de base populacional.

INTRODUCTION: Several factors can lead to changes in dietary practices of the older adults; which contributes with nutritional recommendations not being met. OBJECTIVES: To estimate the prevalence of inadequate dietary fiber consumption and to identify associated factors. METHODOLOGY: Population-based, cross-sectional study that used data from a health survey in the municipality of Campinas, SP, Brazil, held in 2008/2009, in which 1,509 individuals aged 60 or older were assessed. Food consumption was estimated through a 24-hour recall, and the prevalence of inadequacy was calculated according to the Institute of Medicine's cut-off point for total fiber (30 g/day for men and 21 g/day for women). Associated factors were identified using the hierarchical Poisson regression model to estimate the prevalence, adjusted for block distal (sociodemographic) and proximal variables (health and lifestyle indicators). RESULTS: Inadequate consumption was observed in 90.1% of the population, and after adjustments in the final model, this rate remained significantly higher among males (RP = 1.06), seniors with a partner (RP = 1.05), lower income (RP = 0.95), physically inactive (RP = 1.05) and those who would not like to change body weight (RP = 1.05). CONCLUSION: Considering that inadequacy of dietary fiber was very high, the whole 60-year-old or older population must be targeted for nutritional intervention in order to ensure adequate intake of this nutrient.

INTRODUÇÃO: Vários fatores podem gerar mudanças nas práticas alimentares dos idosos, contribuindo para que as recomendações nutricionais não sejam atendidas. OBJETIVO: Estimar a prevalência de inadequação do consumo de fibras alimentares e seus fatores associados. METODOLOGIA: Estudo transversal de base populacional que utilizou dados do Inquérito de Saúde no Município de Campinas, realizado em 2008/2009, no qual foram analisados 1.509 indivíduos ≥ 60 anos. O consumo alimentar foi estimado por meio do recordatório de 24 horas, e foi calculada a prevalência de inadequação de acordo com o ponto de corte para fibras totais do Institute of Medicine de 30 g/dia para homens e 21 g/dia para mulheres. Os fatores associados foram identificados utilizando modelo hierárquico de regressão de Poisson para estimativa das razões de prevalência, ajustados por variáveis de bloco distal (sociodemográficos) e bloco proximal (condições de saúde e indicadores de estilo de vida). RESULTADOS: A inadequação do consumo de fibras alimentares foi observada em 90,1% da população, significantemente maior no sexo masculino (RP = 1,06), em idosos com parceiro (RP = 1,05), de menor renda (RP = 0,95), inativos fisicamente (RP = 1,05) e naqueles que não gostariam de mudar o peso corporal (RP = 1,05). CONCLUSÃO: Considerando que a inadequação de fibras alimentares foi muito elevada, toda a população de 60 anos ou mais deve ser alvo de intervenção nutricional para garantir o aporte adequado desse nutriente.

Elevada prevalência de inadequação do consumo de fibras alimentares em idosos e fatores associados: um estudo de base populacional / High prevalence of inadequate dietary fiber consumption and associated factors in older adults: a population-based study

RESUMO: Introdução: Vários fatores podem gerar mudanças nas práticas alimentares dos idosos, contribuindo para que as recomendações nutricionais não sejam atendidas. Objetivo: Estimar a prevalência de inadequação do consumo de fibras alimentares e seus fatores associados. Metodologia: Estudo transversal de base populacional que utilizou dados do Inquérito de Saúde no Município de Campinas, realizado em 2008/2009, no qual foram analisados 1.509 indivíduos ≥ 60 anos. O consumo alimentar foi estimado por meio do recordatório de 24 horas, e foi calculada a prevalência de inadequação de acordo com o ponto de corte para fibras totais do Institute of Medicine de 30 g/dia para homens e 21 g/dia para mulheres. Os fatores associados foram identificados utilizando modelo hierárquico de regressão de Poisson para estimativa das razões de prevalência, ajustados por variáveis de bloco distal (sociodemográficos) e bloco proximal (condições de saúde e indicadores de estilo de vida). Resultados: A inadequação do consumo de fibras alimentares foi observada em 90,1% da população, significantemente maior no sexo masculino (RP = 1,06), em idosos com parceiro (RP = 1,05), de menor renda (RP = 0,95), inativos fisicamente (RP = 1,05) e naqueles que não gostariam de mudar o peso corporal (RP = 1,05). Conclusão: Considerando que a inadequação de fibras alimentares foi muito elevada, toda a população de 60 anos ou mais deve ser alvo de intervenção nutricional para garantir o aporte adequado desse nutriente.

ABSTRACT: Introduction: Several factors can lead to changes in dietary practices of the older adults; which contributes with nutritional recommendations not being met. Objectives: To estimate the prevalence of inadequate dietary fiber consumption and to identify associated factors. Methodology: Population-based, cross-sectional study that used data from a health survey in the municipality of Campinas, SP, Brazil, held in 2008/2009, in which 1,509 individuals aged 60 or older were assessed. Food consumption was estimated through a 24-hour recall, and the prevalence of inadequacy was calculated according to the Institute of Medicine's cut-off point for total fiber (30 g/day for men and 21 g/day for women). Associated factors were identified using the hierarchical Poisson regression model to estimate the prevalence, adjusted for block distal (sociodemographic) and proximal variables (health and lifestyle indicators). Results: Inadequate consumption was observed in 90.1% of the population, and after adjustments in the final model, this rate remained significantly higher among males (RP = 1.06), seniors with a partner (RP = 1.05), lower income (RP = 0.95), physically inactive (RP = 1.05) and those who would not like to change body weight (RP = 1.05). Conclusion: Considering that inadequacy of dietary fiber was very high, the whole 60-year-old or older population must be targeted for nutritional intervention in order to ensure adequate intake of this nutrient.

Femvertising: publicidade entre mulheres

De maneira criativa marcas buscam o empoderamento feminino e a venda de produtos ao aplicar o Femvertising. Este trabalho analisa as formas de exposição da figura feminina em campanhas publicitárias de cerveja.

Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells.

A series of new chalcones substituted with azide/triazole groups were designed and synthesized, and their cytotoxic activity was evaluated in vitro against the HeLa cell line. O-Alkylation, Claisen-Schmidt condensation and Cu(I)-catalyzed cycloaddition of azides with terminal alkynes were applied in key steps. Fifteen compounds were tested against HeLa cells. Compound 8c was the most active molecule, with an IC50 value of 13.03 µM, similar to the value of cisplatin (7.37 µM).

Sealing ability promoted by three different endodontic sealers.

INTRODUCTION: The aim of this study was to evaluate the apical and coronal seal of endodontic filling promoted by the combined use of Sealer 26/gutta-percha, Endofill/gutta-percha and Resilon/ Epiphany. MATERIALS AND METHODS: A total of 38 extracted human canine teeth were selected; 10 teeth for each test group and 4 for each control group. After conducting conventional endodontic treatment, the teeth were immersed in saline solution for thirty days, and subsequently sealed and stored in India ink for seven days. They were then cleaned and evaluated for infiltration by stereoscopic microscope. The data were statistically analyzed by ANOVA and Bonferroni tests. RESULTS: The results showed no significant differences between the three groups of filling materials used. CONCLUSION: Within the limitations of this in vitro study, no material showed superiority in their apical and coronal seal.

Potencialidades do uso de bancos de dados para informação em saúde: o caso das Terapias Renais Substitutivas (TRS) - morbidade e mortalidade dos pacientes em TRS / Capabilities of the use of database for information on health: the case of Renal Replacement Therapies (RRT)

A coleta sistematizada de informação de pacientes em terapia substitutiva (TRS)tem sido desafiadora na maioria dos países. Apesar de sua relevância, ainda não há um sistema nacional de registro que forneça anualmente dados epidemiológicos e econômicos confiáveis. No Brasil, as TRS são procedimentos faturados por meio do subsistema APAC (A utorização de Procedimentos de Alta Complexidade) que, embora elaborado parafins administrativos, pode subsidiar informações relevantes no monitoramento da linha decuidado a pacientes portadores de doença renal crônica terminal. Este estudo objetivou a descrição do tratamento das informações contidas na Base Nacional em TRS, discussão de sua potencialidade, apresentando o perfil de morbimortalidade dos pacientes e os seus gastos. Trata-se de base de dados conformada para estudo prospectivo não-concorrente, tendo com o fonte de informação a Base Nacional em TRS, desenvolvida a partir da APACe do Sistem a de Informação de Mortalidade (SIM). Compreendeu pacientes incluídos naBase de 01/01/2000 a 31/12/2004 e com pelo menos três meses consecutivos de registros. Foram acompanhados até a ocorrência de óbito ou censurados por término do estudo. O btiveram -se 141.677 pacientes, sendo 51.321 pertencentes à coorte sobrevivente e 90.356 à incidente, para os quais foram apresentados o perfil, gastos e as taxas de prevalência, incidência e letalidade. Assim , a agregação de sistemas de informação tornou possível obter informaçes de morbimortalidade, oferta de serviços e sobrevida de pacientes em TRS,conform e evolução de seu tratamento, além de análises de sua custo-efetividade.

Treatment of postmenopausal osteoporosis in women: a systematic review.

Osteoporosis, a typical disease of the elderly, has become a frequent and relevant public health problem. Several drugs are available for treatment of osteoporosis, some of which are currently dispensed by the Brazilian Unified National Health System. The objective of this study was to present a systematic review of drugs for treatment of osteoporosis, focusing on the adequacy of clinical protocols based on existing evidence in the scientific literature. We conducted a search for randomized clinical trials in PubMed and LILACS that presented results for bone mineral density, incidence of vertebral fractures, and adverse effects. 32 articles met the review's inclusion criteria. Bisphosphonates were reported to have consistently reduced the risk of vertebral fractures. Hormone replacement therapy showed positive outcomes, but its use has been found to increase the risk of cardiovascular disease and breast cancer. Teriparatide and monofluorophosphate also showed efficacy against osteoporosis. Calcium and vitamin D were given to patients as food supplements.