1.
Eur J Anaesthesiol
; 38(3): 311-313, 2021 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33538432
2.
Org Biomol Chem
; 17(3): 519-526, 2019 01 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30569046
RESUMO
A convenient and broadly applicable method for the hydrohalogenation of ynones is described, by the combination of halotrimethylsilanes and tetrafluoroboric acid. Practically, one equivalent of HX (Brønsted acid) and BF3 (Lewis acid) is smoothly generated, which activates the carbonyl compounds. Through this protocol, 42 examples of (Z)-ß-halovinyl carbonyl compounds (Cl, Br and I) were obtained, in good yields and high stereoselectivity having 2-MeTHF as a solvent.