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J Clin Lipidol ; 15(3): 402-422, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33846108

RESUMO

It is now well recognized that South Asians living in the US (SAUS) have a higher prevalence of atherosclerotic cardiovascular disease (ASCVD) that begins earlier and is more aggressive than age-matched people of other ethnicities. SA ancestry is now recognized as a risk enhancer in the US cholesterol treatment guidelines. The pathophysiology of this is not fully understood but may relate to insulin resistance, genetic and dietary factors, lack of physical exercise, visceral adiposity and other, yet undiscovered biologic mechanisms. In this expert consensus document, we review the epidemiology of ASCVD in this population, enumerate the challenges faced in tackling this problem, provide strategies for early screening and education of the community and their healthcare providers, and offer practical prevention strategies and culturally-tailored dietary advice to lower the rates of ASCVD in this cohort.


Assuntos
Povo Asiático , Aterosclerose/prevenção & controle , Anticolesterolemiantes/uso terapêutico , Aterosclerose/complicações , Aterosclerose/etnologia , Aterosclerose/fisiopatologia , Diabetes Mellitus Tipo 2/complicações , Dieta , Feminino , Humanos , Resistência à Insulina , Gordura Intra-Abdominal , Estilo de Vida , Masculino , Educação de Pacientes como Assunto/métodos , Estado Pré-Diabético/complicações , Fatores de Risco , Estados Unidos
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