Evolution of Concepts: Can Personalized Hip Arthroplasty Improve Joint Stability?

Hip arthroplasty procedures are successful and reproducible. However, within the first two post-operative years, hip dislocations are the most common cause for revisions. This is despite the majority of the dislocations having the acetabular component within what is described as the 'safe zone'. The limitations of such boundaries do not take into account the variability of individual hip anatomy and functional pelvic orientation that exist. An alternative concept to address hip instability and improve overall outcomes is functional acetabular orientation. In this review article, we discuss the evolution of concepts, particularly the kinematic alignment technique for hip arthroplasty and the use of large-diameter heads to understand why total hip arthroplasty dislocations occur and how to prevent them.

Monobloc press-fit cups with large-diameter bearings are safe in revision total hip arthroplasty.

BACKGROUND: Instability is a major cause of failure of revision total hip arthroplasty (THA) which can be avoided with the use of monobloc press-fit cups with large diameter heads (LDH). OBJECTIVE: This consecutive case series analyses whether LDH monobloc components are a safe and clinically beneficial option for revision THA. METHODS: This consecutive case series includes 47 revision THA with LDH monobloc acetabular cup. Acetabular bone defects were Paprosky type I (42), type IIA (2) and type IIC (3). The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Forgotten Joint Score (FJS) and the Patient's Joint Perception (PJP) scores were analysed and a radiographic evaluation for signs of implant dysfunction was performed. RESULTS: After a mean follow-up of 4.5 years, there were 5 (10.6%) acetabular cup re-revisions: 2 loss of primary fixation and 3 instabilities. Implant survivorship at 4-years was 89.4% (95% CI: 89.3 to 89.5). Recurrent hip dislocation was reported in 1 patient (2.1%) and remains under conservative treatment. The mean WOMAC and FJS were 19.5 (16.8; 0.0 to 58.3) and 57.3 (28.9; 6.3 to 100.0), respectively. Regarding the PJP, 3 (8.8%) patients perceived their hip as natural, 8 (23.5%) as an artificial joint with no restriction, 14 (41.2%) with minor restriction and 9 (26.5%) with major restriction. CONCLUSION: In cases of revision THA with limited bone loss, press-fit primary fixation with LDH monobloc acetabular components are valuable options that offer excellent mid-term out-comes with low re-revision and joint instability rates.

Modernizing Total Hip Arthroplasty Perioperative Pathways: The Implementation of ERAS-Outpatient Protocol.

Pressure to reduce healthcare costs, limited hospital availability along with improvements in surgical technique and perioperative care motivated many centers to focus on outpatient pathway implementation. However, in many short-stay protocols, the focus has shifted away from aiming to reduce complications and improved rehabilitation, to using length of stay as the main factor of success. To improve patient outcomes and maintain safety, the best way to implement a successful outpatient program would be to combine it with the principles of enhanced recovery after surgery (ERAS), and to improve patient recovery to a level where the patient is able to leave the hospital sooner. This article delivers a case for modernizing total hip arthroplasty perioperative pathways by implementing ERAS-outpatient protocols.

Personalized Hip Joint Replacement with Large Diameter Head: Current Concepts.

Hip arthroplasty is a common procedure in elective orthopaedic surgery that has excellent outcomes. Hip replacement surgery aims to create a "forgotten" joint, i.e., a pain-free joint akin to a native articulation. To achieve such goals, hip arthroplasty must be personalised. This is achieved by restoring: the centre of rotation of the native hip; leg length equality; femoral offset; femoral orientation; soft tissue tension; joint stability with an unrestricted hip range of motion; and having appropriate stress transfer to the bone. In addition, the whole pathway should provide an uneventful and swift postoperative recovery and lifetime implant survivorship with unrestricted activities. At our institution, the preferred option is a personalized total hip arthroplasty (THA) with a large diameter head (LDH) using either monobloc or dual-mobility configuration for the acetabular component. LDH THA offers an impingement-free range of motion and a reduced risk of dislocation. The larger head-neck offset allows for a supraphysiologic range of motion (ROM). This can compensate for a patient's abnormal spinopelvic mobility and surgical imprecision. Additionally, LDH bearing with a small clearance exerts a high suction force, which provides greater hip micro-stability. With appropriate biomechanical reconstruction, LDH THA can restore normal gait parameters. This results in unrestricted activities and higher patient satisfaction scores. We use LDH ceramic on ceramic for our patients with a life expectancy of more than 20 years and use LDH dual mobility bearings for all others.

Kinematic alignment of medial UKA is safe: a systematic review.

PURPOSE: Owing to the improved understanding of knee kinematics and the successful introduction of the kinematic alignment (KA) technique for implanting total knee arthroplasty (TKA), it was recently understood that the "Cartier angle technique" corresponds to a kinematic implantation of the uni-compartmental knee arthroplasty (UKA) components. When compared to the universally spread mechanical alignment (MA) technique for implanting UKA, the KA method generates a more anatomic prosthetic knee that may be clinically advantageous. The aims of this study are to determine if KA UKAs are associated with acceptable functional performance and patient satisfaction (question 1), rates of residual pain and tibia plateau fracture (question 2), and rates of reoperation and revision (question 3), and to define the component orientation and limb alignment as measured on radiograph (question 4), and the stress shielding related bone loss in the proximal tibia (question 5) with KA UKA, and where possible to compare with MA UKA. STUDY HYPOTHESIS: KA UKA generates good clinical outcomes, similar or superior to the ones of MA UKA. METHOD: Systematic review of literature databases were primarily searched using Healthcare Databases Advanced Search (HDAS). Two primary searches were conducted using the electronic databases MEDLINE, EMBASE, and PubMed, and a secondary search was conducted using review articles and bibliography of obtained papers in order to ascertain more material. RESULTS: Nine eligible non-comparative prospective (3) or retrospective (6) cohort studies, which cumulated 593 KA UKAs with follow-up between 3.2 and 12 years, fulfilled the inclusion criteria for this systematic review. The findings demonstrated high Knee Society Score (KSS) (from 87 to 95) and function scores (from 81 to above 91) in addition to patient satisfaction scores of 88%. There was no revision for tibia plateau fracture, 0.8% (5 cases) for unexplained pain tibia, 2.0% (12 cases) for component loosening, and 5.6% (33 cases) for any causes of aseptic failures reported for KA UKA. The prosthetic lower limb and tibia implant alignments were both found to be in slight varus (means between 3 and 5°), and the postoperative joint line and tibia component was shown to be parallel to the floor when standing. The KA UKA components migration, as measured on radiostereometry, was acceptable. DISCUSSION/CONCLUSION: The KA technique is an alternative, personalised, more physiological method for implanting UKA, which could be clinically advantageous when compared to the MA technique. The literature supports the good mid- to long-term clinical safety and good efficacy of KA UKA; however, comparison between KA and MA techniques for UKA was not performed due to limited literature. Further investigations are needed to better define the clinical impact of KA UKA, and the acceptable limits for KA of the UKA tibial component. LEVEL OF EVIDENCE: Level 4; systematic review of level 4 studies.

Specific case consideration for implanting TKA with the Kinematic Alignment technique.

The Kinematic Alignment (KA) technique for total knee arthroplasty (TKA) is an alternative surgical technique aiming to resurface knee articular surfaces.The restricted KA (rKA) technique for TKA applies boundaries to the KA technique in order to avoid reproducing extreme constitutional limb/knee anatomies.The vast majority of TKA cases are straightforward and can be performed with KA in a standard (unrestricted) fashion.There are some specific situations where performing KA TKA may be more challenging (complex KA TKA cases) and surgical technique adaptations should be included.To secure good clinical outcomes, complex KA TKA cases must be preoperatively recognized, and planned accordingly.The proposed classification system describes six specific issues that must be considered when aiming for a KA TKA implantation.Specific recommendations for each situation type should improve the reliability of the prosthetic implantation to the benefit of the patient.The proposed classification system could contribute to the adoption of a common language within our orthopaedic community that would ease inter-surgeon communication and could benefit the teaching of the KA technique. This proposed classification system is not exhaustive and will certainly be improved over time. Cite this article: EFORT Open Rev 2021;6:881-891. DOI: 10.1302/2058-5241.6.210042.

Neck-sparing short femoral stems: A meta-analysis.

BACKGROUND: Neck sparing short femoral stems are supposed to ease restoration of the proximal femoral anatomy and physiological hip biomechanics. This stem design is of particular interest as they have the potential to generate prosthetic hips that have higher functional performance with an improved lifespan, and revise more easily. Unlike previously published meta-analysis, this meta-analysis was initiated to determine if neck sparing short femoral stems compared to conventional stems: (1) resulted in improved functional performance; (2) reduced risk of thigh pain; (3) reduced risk of reoperation/revision, and 4) reduced stress shielding related bone loss in the proximal femur. MATERIAL AND METHODS: Literature databases were searched between 1st January 2005 and 30th March 2019. The primary search was conducted using the electronic databases MEDLINE, EMBASE, PubMed, Open Grey, Trip Pro, Evidence Search, and Cochrane. Eligible studies were assessed for homogeneity, with continuous outcomes expressed as standardized mean difference with 95% confidence interval and dichotomous data as odds-ratio with 95% confidence interval. RESULTS: Ten randomised clinical trials were eligible; these trials included 1259 total hip arthroplasty procedures, inclusive of 616 neck sparing short stems and 643 conventional stems. We were not able to find a significant functional advantage of using neck sparing short stems based on Harris Hip scores (0.0850; 95% CI: -0.03 to 0.20 [p=0.40]) and WOMAC scores (-0.0605; 95% CI: -0.03 to 0.15 [p=0.87]). We found a trend in favour of neck sparing short stems to reduce the risk of thigh pain but this was non significant (odds ratio of 0.11; 95% CI: 0.03 to 0.43 [p=0.178]). Neck sparing short stems were associated with similar early- to mid-term dislocation and revision rates compared to conventional stems with odds ratio of 1.435 (95% CI: 0.545 to 3.780 [p=0.968]) and of 0.581 (95% CI: 0.220 to 1.532 [p=0.972]), respectively. Neck sparing short stems were found to have less bone loss in both Gruen zones 1 and 7 (3.324; 95% CI: -7.683 to 1.036 [p<0.001], and of -4.632; 95% CI: -9682 to 0.418 [p<0.001], respectively). DISCUSSION/CONCLUSION: Neck sparing short femoral stems achieve excellent early to mid-term outcomes in both clinical and radiological outcome scores that are in keeping with conventional stems functionally. Hitherto, results from this meta-analysis suggest that neck-sparing stems may achieve better maintenance of bone mineral density than their conventional counterparts, in addition to fewer cases of thigh pain. LEVEL OF EVIDENCE: I; meta-analysis.

Short-term follow-up of kinematically vs. mechanically aligned total knee arthroplasty with medial pivot components: A case-control study.

INTRODUCTION: The kinematic alignment (KA) technique for total knee arthroplasty (TKA) and the medial pivot (MP) component design are two options promoting a physiologic prosthetic knee kinematics when used in combination that could improve TKA outcomes. Case-control study is initiated to compare the 1-year radio-clinical outcomes between kinematic alignment medial pivot total knee arthroplasty (KA MP-TKAs) and mechanical alignment medial pivot total knee arthroplasty (MA MP-TKA). Goal of a study was to answer the following questions: Do KA MP-TKAs patients have improved functional outcomes compared to MA MP-TKAs patients? (Q1); Do prosthetic knee and lower limb alignments differ between KA and MA patients (Q2)? And does kinematic implantation of MP TKA has higher risk of reoperations and revisions (Q3)? MATERIAL AND METHODS: A case-control study was carried out to compare the 1-year clinical and radiographic outcomes between 24 consecutive KA-TKA patients and 24 matched MA-TKA patients. All patients had implantation with manual instruments and a cemented medial pivot TKA with excision of the PCL. All data were collected prospectively, and outcome scores were patient reported. RESULTS: KA patients had superior values in Forgotten Joint Score (FJS) at 1-year (KA 77 vs. MA 51) (p=0.05) follow-up. After one year KA patients scored better in objective section of the new Knee Society Score (KSS) (p=0.02), and in sport section of the Knee Osteoarthritis Outcome Score (KOOS) (p=0.01). Eleven out of 24 patients (46%) in KA group and 7/24 patients (29%) in MA group had limb alignment out of 180°±3°, whereas 17/24 (70%) of KA patients, and 14/24 (58%) of MA patients had orientation of tibial component with more than 3° of varus. No reoperation or revision occurred in either group. DISCUSSION/CONCLUSION: The KA of MP TKA design seems to have a good efficacy at early-term, with some 1-year functional performance higher to the ones from MA MP TKAs. Further research is needed to define if those early results will last over time. LEVEL OF EVIDENCE: III, case-controlled study.

Third-Generation Minimally Invasive Chevron Akin Osteotomy for Hallux Valgus.

BACKGROUND: Multiple operative techniques have been developed for hallux valgus with varying success. The most recent developments in minimally invasive surgery have evolved into the third-generation minimally invasive chevron Akin (MICA) osteotomy. Good results have been shown from originator centers, but this is one of the first series from a nonoriginator center, and the first to use a validated patient-reported outcome measure. METHODS: Forty consecutive patients undergoing third-generation MICA for hallux valgus were included. Primary outcome measures included Manchester-Oxford Foot Questionnaire (MOXFQ) and American Orthopaedic Foot & Ankle Society (AOFAS) scores and Coughlin satisfaction rates at 12 months. Secondary outcome measures included radiographic parameters, complications, and recurrence rates. RESULTS: At 12 months, the MOXFQ score improved from 58 to 10 and the AOFAS score improved from 48 to 93, with 70% of patients reporting excellent outcomes and 30% good ones. Two cases started as mild, 29 cases as moderate, and 9 cases as severe as defined by radiographic criteria. Hallux valgus angles improved from 32 degrees to 12 degrees, and intermetatarsal angles improved from 13 degrees to 7 degrees. There were 4 cases of Akin screw removal for soft tissue irritation. There were no other complications, including recurrence. CONCLUSION: The third-generation MICA technique was a safe and effective approach to treating hallux valgus. Further research should focus on long-term outcomes and comparative data with other commonly performed operative techniques. LEVEL OF EVIDENCE: Level IV, case series.

The Risotto sign - a severe inflammatory bursitis with rice body formation, complicating a rotator cuff repair with a bioabsorbable suture anchor.

There is an association between inflammatory bursitis with rice body formation and use of bioabsorbable suture anchors.

Improving dosing of gentamicin in the obese patient: a 3-cycle drug chart and case note audit.

OBJECTIVES: To assess the use of an electronic dose calculator to improve accuracy in the use of a complex Gentamicin prescription policy and assess turnaround time of blood sampling to dose delivery in an NHS hospital. DESIGN: Retrospective review of drug chart, case notes and hospital antibiotic database. SETTING: University Hospitals Bristol, UK PARTICIPANTS: Patients receiving once daily intravenous gentamicin using the trust protocol, during the same time window for 3 consecutive years. MAIN OUTCOME MEASURES: i) Accuracy of dose and frequency prescription of Gentamicin. ii) Time frame for measurement of serum Gentamicin levels. RESULTS: Following the introduction of the online calculator, prescribing errors in obese patients dropped from 43% to 20%, a similar level as in non-obese patients. Errors in frequency calculations dropped from 12.8% to 4%. On average, drug doses could be administered within 2.5 hours of a blood sample being taken. CONCLUSIONS: Online tools can be used to improve prescribing for the complex dosing policies that will increasingly been required to tailor prescribing in obese patients. Serum gentamicin levels can be measured within a 2.5 hour time frame in the environment of an NHS hospital.

Acute tendon injuries in the hand and their management.

Acute tendon injuries to the hand are common. In the UK, there are approximately 12000 inpatient admissions annually for injuries to the tendons and muscles of the hand and wrist (Dew, 2009). Hand injuries involving the dominant hand can cause long-term disability if not appropriately managed. Diagnosis of tendon injuries in the hand relies on careful clinical assessment, particularly if flexor and extensor tendon injuries are not to be missed. This article describes the tendon structure, explains the causes of tendon injury and discusses their assessment and management for a foundation level doctor who will face these injuries regularly whether in primary care or the emergency department.

Central dislocation of the hip secondary to insufficiency fracture.

We present a case report of a 45-year old man who sustained a central dislocation of the hip secondary to an insufficiency fracture of the acetabulum. At the time of presentation he was on alendronate therapy for osteoporosis which had been previously investigated. CT scanning of the pelvis was useful for pre-operative planning which confirmed collapse of the femoral head but no discontinuity of the pelvis. The femoral head was morcellized and used as bone graft for the acetabular defect and an uncemented total hip replacement was performed.