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1.
Nat Commun ; 3: 851, 2012 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-22617291

RESUMO

Illegal, Unreported and Unregulated fishing has had a major role in the overexploitation of global fish populations. In response, international regulations have been imposed and many fisheries have been 'eco-certified' by consumer organizations, but methods for independent control of catch certificates and eco-labels are urgently needed. Here we show that, by using gene-associated single nucleotide polymorphisms, individual marine fish can be assigned back to population of origin with unprecedented high levels of precision. By applying high differentiation single nucleotide polymorphism assays, in four commercial marine fish, on a pan-European scale, we find 93-100% of individuals could be correctly assigned to origin in policy-driven case studies. We show how case-targeted single nucleotide polymorphism assays can be created and forensically validated, using a centrally maintained and publicly available database. Our results demonstrate how application of gene-associated markers will likely revolutionize origin assignment and become highly valuable tools for fighting illegal fishing and mislabelling worldwide.


Assuntos
Polimorfismo de Nucleotídeo Único/genética , Animais , Conservação dos Recursos Naturais , Ecologia , Pesqueiros , Peixes/genética
2.
J Manipulative Physiol Ther ; 32(1): 93-8, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19121467

RESUMO

OBJECTIVE: This case study reports on selected measures of locomotion (running) in a 5-year-old patient with xeroderma pigmentosum after chiropractic care. CLINICAL FEATURE: A 5-year-old female patient (16.4 kg, 99.1 cm) with xeroderma pigmentosum (type A) volunteered to participate in the experiment with the consent of her parents. The patient had well-documented signs of delayed fine motor (eg, difficulty with writing, coloring, cutting) and gross motor control (eg, balance and coordination dysfunction and falling while running), and delayed speech. INTERVENTION AND OUTCOMES: Trunk forward lean angles, step lengths, and hip horizontal translations were assessed by video as the participant ran as fast as possible down a laboratory runway. After chiropractic manipulation (adjustments), the patient reduced the trunk forward lean angle to become more vertical (P = .000). In addition, the patient experienced an increase in step length (P = .031). No significant change in lateral translation was observed after the intervention. CONCLUSION: For this patient with xeroderma pigmentosum, chiropractic manipulation (adjustments) resulted in immediate changes in running performance. Further investigation is needed to examine the effect of chiropractic on locomotion in both symptomatic and asymptomatic patients.


Assuntos
Marcha/fisiologia , Manipulação Quiroprática , Corrida/fisiologia , Xeroderma Pigmentoso/terapia , Pré-Escolar , Feminino , Humanos , Transtornos das Habilidades Motoras/etiologia , Equilíbrio Postural/fisiologia , Distúrbios da Fala/etiologia , Xeroderma Pigmentoso/complicações , Xeroderma Pigmentoso/fisiopatologia
3.
J Manipulative Physiol Ther ; 29(4): 257-66, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16690379

RESUMO

OBJECTIVE: To investigate the effect of chiropractic adjustments on movement time using Fitts Law. METHODS: This was a prospective, randomized controlled trial. Ten patients from a private chiropractic practice participated. Participants in the treatment group received high-velocity, low-amplitude chiropractic adjustments to areas of joint dysfunction (chiropractic subluxation). A nonintervention group was used to control for improvement resulting from time and practice effects. Movement time was measured as participants moved a cursor onto a target appearing on a computer screen. A range of target widths and target distances were used to vary the index of difficulty. RESULTS: All participants in the experimental group had significantly improved movement times following spinal adjustments compared with only 1 participant in the control group. The average improvement in movement time for the experimental group was 183 ms, a 9.2% improvement, whereas the average improvement in movement time for the control group was 29 ms, a 1.7% improvement. The difference (improvement) scores after the intervention were significantly greater for the chiropractic group compared with the control group as measured by a 2-tailed independent samples t test (P < .05). CONCLUSION: The results of this study demonstrated a significant improvement in movement time with chiropractic care. These results suggest that spinal adjustments may influence motor behavior.


Assuntos
Dor Lombar/terapia , Manipulação Quiroprática/métodos , Adulto , Feminino , Humanos , Masculino , Matemática , Pessoa de Meia-Idade , Projetos Piloto , Estudos Prospectivos , Fatores de Tempo
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