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Environ Toxicol Pharmacol ; 105: 104349, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38135201

RESUMO

The objectives of this study were to evaluate the exposure to a diet naturally contaminated with mycotoxins on lactation performance, animal health, and the ability to sequester agents (SA) to reduce the human exposure to AFM1. Sixty healthy lactating Holstein cows were randomly assigned to two groups: naturally contaminated diet without and with the addition of a SA (20 g/cow/d AntitoxCooPil® -60% zeolite-40% cell wall-). Each cow was monitored throughout lactation. The concentration of aflatoxin B1 (AFB1) in feed and M1 (AFM1) in milk, health status, and productive and reproductive parameters were measured. AFB1 concentration in feed was very low (2.31 µg/kgDM). The addition of SA reduced the milk AFM1 concentrations (0.016 vs. 0.008 µg/kg) and transfer rates (2.19 vs. 0.77%). No differences were observed in health status, production and reproduction performance. The inclusion of SA in the diet of dairy cows reduce the risk in the most susceptible population.


Assuntos
Aflatoxina M1 , Contaminação de Alimentos , Lactação , Leite , Sequestrantes , Animais , Bovinos , Feminino , Aflatoxina B1/toxicidade , Aflatoxina B1/análise , Aflatoxina M1/análise , Aflatoxina M1/antagonistas & inibidores , Ração Animal/análise , Ração Animal/toxicidade , Dieta/veterinária , Contaminação de Alimentos/análise , Contaminação de Alimentos/prevenção & controle , Leite/química , Sequestrantes/administração & dosagem , Distribuição Aleatória
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