RESUMO
This article reviews which parts of the alcohol administration methodology were reported in 90 alcohol studies on humans published from 1994 to 1995. although several subject characteristics such as gender were regularly reported, other variables that can influence pharmacokinetics and responses to alcohol were not consistently reported. It is suggested that guidelines for reporting human alcohol administration studies be created and that journal editors and funding agencies require submissions to meet minimum standards for describing the study methodology. Potential guidelines are presented.
Assuntos
Consumo de Bebidas Alcoólicas , Etanol/administração & dosagem , Projetos de Pesquisa/normas , Fatores Etários , Alcoolismo/diagnóstico , Alcoolismo/psicologia , Peso Corporal , Etanol/farmacocinética , Etanol/farmacologia , Feminino , Guias como Assunto , Humanos , Masculino , Seleção de Pacientes , Publicações Periódicas como Assunto/normas , Placebos , Fatores Sexuais , Comportamento SocialRESUMO
This article reviews the 61 alcohol treatment outcome studies published from 1989-1993 with respect to methodology. Although better assessment of subjects' pretreatment characteristics was noted, a minority of studies met even the basic requirements of experimental studies. Further, some reversals of methodological progress were observed in several areas, particularly in collecting outcome data from multiple sources. It is suggested that funding agencies and journal editors require that submissions meet minimum standards for adequate outcome evaluation.
