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1.
Chem Commun (Camb) ; 49(53): 5954-6, 2013 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-23715176

RESUMO

We report the development of molecularly imprinted polyacrylamide nanoparticles that bind to and neutralize the activity of cytotoxins present in the venom of the Mozambique Spitting Cobra (Naja mossambica mossambica). The binding activity of these nanoparticles is avid and specific. These findings hold promise for the development of a synthetic antivenom.


Assuntos
Resinas Acrílicas/química , Proteínas Cardiotóxicas de Elapídeos/química , Citotoxinas/química , Nanopartículas/química , Impressão Molecular
2.
J Chem Educ ; 90(3): 326-331, 2013 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-23585695

RESUMO

A chemical research program at a public high school has been developed. The full-year Advanced Chemical Research class (ACR) in the high school enrolls 20 to 30 seniors each year, engaging them in long-term experimental projects. Through partnerships involving university scientists, ACR high school students have had the opportunity to explore a number of highly sophisticated original research projects. As an example of the quality of experimental work made possible through these high school-university partnerships, this article describes the development of a novel method for the oxidation of ethidium bromide, a mutagen commonly used in molecular biology. Data collected from ACR alumni show that the ACR program is instrumental in encouraging students to pursue careers in scientific fields and in creating life-long problem-solvers.

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