[The effect of x-ray radiation and hypoxia on the proteolytic activity of the normal rat spleen and during tumor growth]. / Vliianie rentgenovskogo izlucheniia i gipoksii na proteoliticheskuiu aktivnost' selezenki krys v norme i pri opukholevom roste.

The influence of X-radiation on activity of lysosomal enzymes (D, L, H cathepsins) in rat spleen tissue and in inoculated rat sarcoma 45 has been investigated. Intact rats and rats with tumors were subjected to whole-body and sarcoma 45 to local irradiation with doses of 0.155 C/kg and 0.31 C/kg in conditions of breathing gas hypoxic mixture containing 90% of nitrogen and 10% of oxygen (GHM-10). The combined exposure to radiation and GHM-10 was shown to produce a certain protective action (e.g. normalized cathepsin activity) in the spleen. In the tumor tissue the protective effect of GHM-10 was absent.

[Soluble and membrane glycoproteins of the rat brain in radiation injury]. / Rastvorimye y membrannye glikoproteiny golovnogo mozga krys pri luchevom porazhenii.

The content of total protein, glycoproteins, and N-acetylneuraminic acid in different membrane fractions of rat brain tissues was studied 60 min and 24 h following X-irradiation with a dose of 0.31 C/kg. A slight increase in the amount of glycoproteins was noted upon electrophoresis due to the occurrence of low molecular weight carbohydrate-containing proteins. The derangement of the membrane glycoprotein structure is supposed to be one on the causes of radiation destruction of membranes.

[Ammonia content of the brain, liver and blood of rats in radiation injury]. / Soderzhanie ammiaka v golovnom mozge, pecheni i krovi krys pri luchevom porazhenii.

The neuroparalytic syndrome induced by ammonia was compared with the X-radiation-induced cerebral syndrome. It is suggested that the accumulation of ammonia in the brain and liver of rats is one of the reasons for the similarity of the studied syndromes. The fact that ammonia is bound by glutamic acid indicates that the latter is involved in the mechanisms of ammonia utilization and in the radioprotective properties manifestation.

[Interaction of external and internal factors in the manifestations and formation of psychopathies and pathological personality development]. / Nekotorye voprosy vzaimodeistviia vneshnikh i vnutrennikh faktorov v proiavlenii i formirovanii psikhopatii i patologicheskogo razvitiia lichnosti

The authors substantiate the concept that the material and pathophysiological substrate of psychopathy is the pathological variant of the highest nervous activity type, on the basis of which psychopathy appears and begins to form. They attempt to answer some questions concerning the correlation between exogenous and endogenous origins of psychopathy. A delineation between psychopathy and normal variants on the one hand and accentuated personalities and pathocharacterological personality development on the other one is made.