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1.
Opt Lett ; 49(9): 2373-2376, 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38691722

RESUMO

We designed a grating coupler optimized for normal incidence and numerically demonstrate near-unity coupling in a standard 220-nm-thick silicon-on-insulator (SOI) technology. Our design breaks the vertical symmetry within the grating region by implementing three scattering sites per local period. This technique removes the need for bottom reflectors or additional material layers and can be realized using only two lithography masks. Using adjoint method-based optimization, we engineer the coupling spectrum of the grating, balancing the trade-off between peak efficiency and bandwidth. Using this technique, we simulate three devices with peak coupling efficiencies ranging between 93.4 (-0.3 dB) and 98.6% (-0.06 dB) with corresponding 1 dB bandwidths between 48 and 8 nm all centered around 1.55 µm.

2.
Phys Rev Lett ; 132(8): 085001, 2024 Feb 23.
Artigo em Inglês | MEDLINE | ID: mdl-38457729

RESUMO

We demonstrate a silicon-based electron accelerator that uses laser optical near fields to both accelerate and confine electrons over extended distances. Two dielectric laser accelerator (DLA) designs were tested, each consisting of two arrays of silicon pillars pumped symmetrically by pulse front tilted laser beams, designed for average acceleration gradients 35 and 50 MeV/m, respectively. The DLAs are designed to act as alternating phase focusing (APF) lattices, where electrons, depending on the electron-laser interaction phase, will alternate between opposing longitudinal and transverse focusing and defocusing forces. By incorporating fractional period drift sections that alter the synchronous phase between ±60° off crest, electrons captured in the designed acceleration bucket experience half the peak gradient as average gradient while also experiencing strong confinement forces that enable long interaction lengths. We demonstrate APF accelerators with interaction lengths up to 708 µm and energy gains up to 23.7±1.07 keV FWHM, a 25% increase from starting energy, demonstrating the ability to achieve substantial energy gains with subrelativistic DLA.

3.
Science ; 380(6643): 398-404, 2023 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-37104594

RESUMO

Integrated photonic neural networks provide a promising platform for energy-efficient, high-throughput machine learning with extensive scientific and commercial applications. Photonic neural networks efficiently transform optically encoded inputs using Mach-Zehnder interferometer mesh networks interleaved with nonlinearities. We experimentally trained a three-layer, four-port silicon photonic neural network with programmable phase shifters and optical power monitoring to solve classification tasks using "in situ backpropagation," a photonic analog of the most popular method to train conventional neural networks. We measured backpropagated gradients for phase-shifter voltages by interfering forward- and backward-propagating light and simulated in situ backpropagation for 64-port photonic neural networks trained on MNIST image recognition given errors. All experiments performed comparably to digital simulations ([Formula: see text]94% test accuracy), and energy scaling analysis indicated a route to scalable machine learning.

4.
Micromachines (Basel) ; 13(8)2022 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-36014282

RESUMO

Micro-actuators driven on resonance maximize reach and speed; however, due to their sensitivity to environmental factors (e.g., temperature and air pressure), the amplitude and phase response must be monitored to achieve an accurate actuator position. We introduce an MEMS (microelectromechanical system) amplitude and phase monitor (MAPM) with a signal-to-noise ratio of 51 dB and 11.0 kHz bandwidth, capable of simultaneously driving and sensing the movement of 1D and 2D electrostatically driven micro-actuators without modifying the chip or its packaging. The operational principle is to electromechanically modulate the amplitude of a high-frequency signal with the changing capacitance of the micro-actuator. MAPM operation is characterized and verified by simultaneously measuring the amplitude and phase frequency response of commercial micromirrors. We demonstrate that the MAPM circuitry is insensitive to complex relationships between capacitance and position of the MEMS actuators, and it is capable of giving real-time read-out of the micromirror motion. Our measurements also reveal and quantify observations of phase drift and crosstalk in 2D resonant operation. Measurements of phase changes over time under normal operation also verify the need for phase monitoring. The open-loop, high-sensitivity position sensor enables detailed characterization of dynamic micro-actuator behavior, leading to new insights and new types of operation, including improved control of nonlinear motion.

5.
Microsyst Nanoeng ; 8: 69, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35769230

RESUMO

Immersion optics enable creation of systems with improved optical concentration and coupling by taking advantage of the fact that the luminance of light is proportional to the square of the refractive index in a lossless optical system. Immersion graded index optical concentrators, that do not need to track the source, are described in terms of theory, simulations, and experiments. We introduce a generalized design guide equation which follows the Pareto function and can be used to create various immersion graded index optics depending on the application requirements of concentration, refractive index, height, and efficiency. We present glass and polymer fabrication techniques for creating broadband transparent graded index materials with large refractive index ranges, (refractive index ratio)2 of ~2, going many fold beyond what is seen in nature or the optics industry. The prototypes demonstrate 3x optical concentration with over 90% efficiency. We report via functional prototypes that graded-index-lens concentrators perform close to the theoretical maximum limit and we introduce simple, inexpensive, design-flexible, and scalable fabrication techniques for their implementation.

6.
Phys Rev Lett ; 127(16): 164802, 2021 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-34723609

RESUMO

Compressing electron pulses is important in many applications of electron beam systems. In this study, we propose to use optical beat notes to compress electron pulses. The beat frequency is chosen to match the initial electron pulse duration, which enables the compression of electron pulses with a wide range of durations. This functionality extends the optical control of electron beams, which is important in compact electron beam systems such as dielectric laser accelerators. We also find that the dominant frequency of the electron charge density changes continuously along its drift trajectory, which may open up new opportunities in coherent interaction between free electrons and quantum or classical systems.

7.
Sci Rep ; 11(1): 20011, 2021 10 08.
Artigo em Inglês | MEDLINE | ID: mdl-34625586

RESUMO

Two-dimensional, resonant scanners have been utilized in a large variety of imaging modules due to their compact form, low power consumption, large angular range, and high speed. However, resonant scanners have problems with non-optimal and inflexible scanning patterns and inherent phase uncertainty, which limit practical applications. Here we propose methods for optimized design and control of the scanning trajectory of two-dimensional resonant scanners under various physical constraints, including high frame-rate and limited actuation amplitude. First, we propose an analytical design rule for uniform spatial sampling. We demonstrate theoretically and experimentally that by expanding the design space, the proposed designs outperform previous designs in terms of scanning range and fill factor. Second, we show that we can create flexible scanning patterns that allow focusing on user-defined Regions-of-Interest (RoI) by modulation of the scanning parameters. The scanning parameters are found by an optimization algorithm. In simulations, we demonstrate the benefits of these designs with standard metrics and higher-level computer vision tasks (LiDAR odometry and 3D object detection). Finally, we experimentally implement and verify both unmodulated and modulated scanning modes using a two-dimensional, resonant MEMS scanner. Central to the implementations is high bandwidth monitoring of the phase of the angular scans in both dimensions. This task is carried out with a position-sensitive photodetector combined with high-bandwidth electronics, enabling fast spatial sampling at [Formula: see text] Hz frame-rate.

8.
J Biomed Opt ; 25(10)2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-33098281

RESUMO

SIGNIFICANCE: Axially swept light sheet microscopy is used for deconvolution-free, high-resolution 3D imaging, but usually the axial scan mechanism reduces the top imaging speed. Phased arrays (PAs) for axial scanning enable both high resolution and high speed. AIM: A high-speed PA with an update rate faster than the camera row read time is used to track the rolling shutter at camera-limited rates. APPROACH: The point spread function is evaluated to ensure sub-micron isotropic resolution, and the technique is demonstrated on a live Drosophila embryo. RESULTS: Isotropic resolution is shown down to 720 ± 55 nm in all three spatial dimensions. With an update rate of 2.85 µs, the PA tracks the camera sensor rolling shutter at camera-limited rates. Features in the Drosophila embryo are resolved clearly compared with the equivalent static light sheet case. The random-access nature of the PA enables a camera sensor readout in the same direction for each frame to maintain even temporal sampling in image sequences with no speed loss. CONCLUSIONS: Use of PAs is compatible with axially swept light sheet microscopy and offers significant improvements in speed.


Assuntos
Sistemas Microeletromecânicos , Microscopia , Imageamento Tridimensional
9.
Opt Express ; 28(10): 14948-14962, 2020 May 11.
Artigo em Inglês | MEDLINE | ID: mdl-32403527

RESUMO

Single-photon light detection and ranging (LiDAR) techniques use emerging single-photon detectors (SPADs) to push 3D imaging capabilities to unprecedented ranges. However, it remains challenging to robustly estimate scene depth from the noisy and otherwise corrupted measurements recorded by a SPAD. Here, we propose a deep sensor fusion strategy that combines corrupted SPAD data and a conventional 2D image to estimate the depth of a scene. Our primary contribution is a neural network architecture-SPADnet-that uses a monocular depth estimation algorithm together with a SPAD denoising and sensor fusion strategy. This architecture, together with several techniques in network training, achieves state-of-the-art results for RGB-SPAD fusion with simulated and captured data. Moreover, SPADnet is more computationally efficient than previous RGB-SPAD fusion networks.

10.
Science ; 367(6473): 79-83, 2020 01 03.
Artigo em Inglês | MEDLINE | ID: mdl-31896715

RESUMO

Particle accelerators represent an indispensable tool in science and industry. However, the size and cost of conventional radio-frequency accelerators limit the utility and reach of this technology. Dielectric laser accelerators (DLAs) provide a compact and cost-effective solution to this problem by driving accelerator nanostructures with visible or near-infrared pulsed lasers, resulting in a 104 reduction of scale. Current implementations of DLAs rely on free-space lasers directly incident on the accelerating structures, limiting the scalability and integrability of this technology. We present an experimental demonstration of a waveguide-integrated DLA that was designed using a photonic inverse-design approach. By comparing the measured electron energy spectra with particle-tracking simulations, we infer a maximum energy gain of 0.915 kilo-electron volts over 30 micrometers, corresponding to an acceleration gradient of 30.5 mega-electron volts per meter. On-chip acceleration provides the possibility for a completely integrated mega-electron volt-scale DLA.

11.
IEEE Trans Med Imaging ; 39(4): 1127-1137, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31567074

RESUMO

We present software-based methods for automatic phase control and for mosaicing high-speed, Lissajous-scanned images. To achieve imaging speeds fast enough for mosaicing, we first increase the image update rate tenfold from 3 to 30 Hz, then vertically interpolate each sparse image in real-time to eliminate fixed pattern noise. We validate our methods by imaging fluorescent beads and automatically maintaining phase control over the course of one hour. We then image fixed mouse brain tissues at varying update rates and compare the resulting mosaics. Using reconstructed image data as feedback for phase control eliminates the need for phase sensors and feedback controllers, enabling long-term imaging experiments without additional hardware. Mosaicing subsampled images results in video-rate imaging speeds, nearly fully recovered spatial resolution, and millimeter-scale fields of view.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Microscopia Confocal/métodos , Software , Gravação em Vídeo/métodos , Algoritmos , Animais , Encéfalo/diagnóstico por imagem , Camundongos
12.
J Biomed Opt ; 24(4): 1-6, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30968649

RESUMO

We demonstrate improved optical sectioning in light sheet fluorescence microscopy using tunable structured illumination (SI) frequencies to optimize image quality in scattering specimens. The SI patterns are generated coherently using a one-dimensional spatial light modulator for maximum pattern contrast, and the pattern spatial frequency is adjustable up to half the incoherent cutoff frequency of our detection objective. At this frequency, we demonstrate background reductions of 2 orders of magnitude.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Microscopia de Fluorescência , Animais , Colo/diagnóstico por imagem , Colo/patologia , Desenho de Equipamento , Luz , Camundongos , Microscopia de Fluorescência/instrumentação , Microscopia de Fluorescência/métodos , Imagens de Fantasmas , Espalhamento de Radiação
13.
Phys Rev Lett ; 122(10): 104801, 2019 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-30932681

RESUMO

We demonstrate a laser-driven, tunable electron lens fabricated in monolithic silicon. The lens consists of an array of silicon pillars pumped symmetrically by two 300 fs, 1.95 µm wavelength, nJ-class laser pulses from an optical parametric amplifier. The optical near field of the pillar structure focuses electrons in the plane perpendicular to the pillar axes. With 100±10 MV/m incident laser fields, the lens focal length is measured to be 50±4 µm, which corresponds to an equivalent quadrupole focusing gradient B^{'} of 1.4±0.1 MT/m. By varying the incident laser field strength, the lens can be tuned from a 21±2 µm focal length (B^{'}>3.3 MT/m) to focal lengths on the centimeter scale.

14.
Phys Rev Lett ; 123(26): 264802, 2019 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-31951436

RESUMO

Net acceleration of attosecond-scale electron pulses is critical to the development of on-chip accelerators. We demonstrate a silicon-based laser-driven two-stage accelerator as an injector stage prototype for a Dielectric Laser Accelerator (DLA). The first stage converts a 57-keV (500±100)-fs (FWHM) electron pulse into a pulse train of 700±200 as (FWHM) microbunches. The second stage harnesses the tunability of dual-drive DLA to perform both a net acceleration and a streaking measurement. In the acceleration mode, the second stage increases the net energy of the electron pulse by 200 eV over 12.25 µm. In the deflection mode, the microbunch temporal profile is analyzed by a direct streaking measurement with 200 as resolution. This work provides a demonstration of a novel, on-chip method to access the attosecond regime, opening new paths towards attosecond science using DLA.

15.
Opt Lett ; 43(21): 5455-5458, 2018 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-30383030

RESUMO

We demonstrate a high-speed linear microelectromechanical systems (MEMS) phase modulator capable of random access scanning at 350 kHz, so that any state can be accessed in 2.9 µs from any other state. 670 scan lines with a .87 deg field of view (FOV) are demonstrated in a Fourier regime, with a projected far-field response of 660 lines with an 18 deg FOV after magnification.

16.
Opt Lett ; 43(12): 2803-2806, 2018 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-29905693

RESUMO

Low-loss photonic crystal (PC) mirrors exhibit positive and negative Goos-Hänchen shift (GHS) due to the strong angular and wavelength dependencies of their reflected phase. This Letter demonstrates the existence of large positive and negative GHS in PC mirrors through theoretical, numerical, and experimental approaches. A simple algebraic relation shows that positive effective thickness yields positive (negative) GHS for resonances that blue (red) shift with angle, while the opposite is true for interfaces with negative effective thickness. Spatiotemporal coupled-mode theory demonstrates the above relation for simple systems with one or two resonance modes, and it also shows the existence of both positive and negative GHS. These effects are numerically and experimentally verified in complex PCs with several resonance modes.

17.
Opt Lett ; 43(9): 2181-2184, 2018 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-29714784

RESUMO

We present the demonstration of phase-dependent laser acceleration and deflection of electrons using a symmetrically driven silicon dual pillar grating structure. We show that exciting an evanescent inverse Smith-Purcell mode on each side of a dual pillar grating can produce hyperbolic cosine acceleration and hyperbolic sine deflection modes, depending on the relative excitation phase of each side. Our devices accelerate sub-relativistic 99.0 keV kinetic energy electrons by 3.0 keV over a 15 µm distance with accelerating gradients of 200 MeV/m with 40 nJ, 300 fs, 1940 nm pulses from an optical parametric amplifier. These results represent a significant step towards making practical dielectric laser accelerators for ultrafast, medical, and high-energy applications.

18.
IEEE Trans Med Imaging ; 37(4): 929-940, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29610072

RESUMO

Automated cell segmentation and tracking is essential for dynamic studies of cellular morphology, movement, and interactions as well as other cellular behaviors. However, accurate, automated, and easy-to-use cell segmentation remains a challenge, especially in cases of high cell densities, where discrete boundaries are not easily discernable. Here, we present a fully automated segmentation algorithm that iteratively segments cells based on the observed distribution of optical cell volumes measured by quantitative phase microscopy. By fitting these distributions to known probability density functions, we are able to converge on volumetric thresholds that enable valid segmentation cuts. Since each threshold is determined from the observed data itself, virtually no input is needed from the user. We demonstrate the effectiveness of this approach over time using six cell types that display a range of morphologies, and evaluate these cultures over a range of confluencies. Facile dynamic measures of cell mobility and function revealed unique cellular behaviors that relate to tissue origins, state of differentiation, and real-time signaling. These will improve our understanding of multicellular communication and organization.


Assuntos
Algoritmos , Técnicas Citológicas/métodos , Processamento de Imagem Assistida por Computador/métodos , Microscopia/métodos , Linhagem Celular , Células Cultivadas , Humanos
19.
Opt Lett ; 43(3): 599-602, 2018 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-29400850

RESUMO

An optimization algorithm for preparing display-ready holographic elements (hogels) to synthesize a light field is outlined, and proof of concept is experimentally demonstrated. This method allows for higher-rank factorization, which can be used for time-multiplexing multiple frames for improved image quality, using phase-only and fully complex modulation with a single spatial light modulator.

20.
Microsyst Nanoeng ; 4: 18, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-31057906

RESUMO

Complex optical devices including aspherical focusing mirrors, solar concentrator arrays, and immersion lenses were 3D printed using commercial technology and experimentally demonstrated by evaluating surface roughness and shape. The as-printed surfaces had surface roughness on the order of tens of microns. To improve this unacceptable surface quality for creating optics, a polymer smoothing technique was developed. Atomic force microscopy and optical profilometry showed that the smoothing technique reduced the surface roughness to a few nanometers, consistent with the requirements of high-quality optics, while tests of optical functionality demonstrated that the overall shapes were maintained so that near theoretically predicted operation was achieved. The optical surface smoothing technique is a promising approach towards using 3D printing as a flexible tool for prototyping and fabrication of miniaturized high-quality optics.

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