RESUMO
PURPOSE: To assess patient satisfaction with autologous serum tears (AST) for the treatment of dry eye disease (DED). METHODS: A prospective, observational case-series, including 100 participants who were treated with AST for DED. The five-item Dry Eye Questionnaire (DEQ-5), Symptom Assessment in Dry Eye (SANDE) Questionnaire, and the Treatment Satisfaction Questionnaire for Medication (TSQM) were used to assess DED symptoms and patients' treatment satisfaction. RESULTS: The duration of AST treatment was 1-6 months in 25%, 6-12 months in 24%, 1-2 years in 22%, and 2-3 years in 29% of the participants. The mean cumulative DEQ-5 score was 12.7⯱â¯3.8 and 65% of the participants scored ≥12, which may suggest an underlying diagnosis of Sjögren's syndrome. The use of other treatments was significantly reduced after the use of AST (Pâ¯<â¯0.001). The mean total SANDE score improved from 79.5⯱â¯21.8, 95% CI [75.2, 83.8] before to 42.2⯱â¯23.2, 95% CI [37.6, 46.8] after using AST (Pâ¯<â¯0.001). The mean TSQM treatment efficacy, convenience, and global satisfaction scores were 73.1⯱â¯17.2, 95% CI [69.6, 76.5], 72.5⯱â¯17.5, 95% CI [69.0, 76.0], and 74.6⯱â¯22.7, 95% CI [70.1, 79.0]. No patients reported any side effects. CONCLUSION: Autologous serum tears treatment in severe dry eye disease significantly reduced dry eye symptoms, with high patients' satisfaction scores.
Assuntos
Síndromes do Olho Seco/terapia , Soro , Lágrimas , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Soluções Oftálmicas , Medidas de Resultados Relatados pelo Paciente , Satisfação do Paciente , Estudos Prospectivos , Fatores de Tempo , Resultado do TratamentoRESUMO
Transverse colon volvulus is a rarely encountered disorder that is difficult to diagnose preoperatively. The anatomic, physiological, and mechanical factors that predispose patients to this problem are discussed as well as various therapies. The radiographic appearance is also reviewed.