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1.
Nutrients ; 13(8)2021 Aug 11.
Artigo em Inglês | MEDLINE | ID: mdl-34444914

RESUMO

There is little data on the experience of managing pediatric Intestinal Failure (IF) in Latin America. This study aimed to identify and describe the current organization and practices of the IF teams in Latin America and the Caribbean. An online survey was sent to inquire about the existence of IF teams that managed children on home parenteral nutrition (HPN). Our questionnaire was based on a previously published European study with a similar goal. Twenty-four centers with pediatric IF teams in eight countries completed the survey, representing a total number of 316 children on HPN. The median number of children on parenteral nutrition (PN) at home per team was 5.5 (range 1-50). Teams consisted of the following members: pediatric gastroenterologist and a pediatric surgeon in all teams, dietician (95.8%), nurse (91.7%), social worker (79.2%), pharmacist (70.8%), oral therapist (62.5%), psychologist (58.3%), and physiotherapist (45.8%). The majority of the centers followed international standards of care on vascular access, parenteral and enteral nutrition, and IF medical and surgical management, but a significant percentage reported inability to monitor micronutrients, like vitamins A (37.5%), E (41.7%), B1 (66.7%), B2 (62.5%), B6 (62.5%), active B12 (58.3%); and trace elements-including zinc (29.2%), aluminum (75%), copper (37.5%), chromium (58.3%), selenium (58.3%), and manganese (58.3%). Conclusion: There is wide variation in how IF teams are structured in Latin America-while many countries have well-established Intestinal rehabilitation programs, a few do not follow international standards. Many countries did not report having an IF team managing pediatric patients on HPN.


Assuntos
Gastroenterologia/estatística & dados numéricos , Enteropatias/terapia , Equipe de Assistência ao Paciente/estatística & dados numéricos , Pediatria/estatística & dados numéricos , Padrões de Prática Médica/estatística & dados numéricos , Adolescente , Região do Caribe , Criança , Pré-Escolar , Feminino , Gastroenterologia/métodos , Humanos , Lactente , Recém-Nascido , América Latina , Masculino , Nutrição Parenteral no Domicílio/estatística & dados numéricos , Pediatria/métodos , Inquéritos e Questionários
2.
Rev Chil Pediatr ; 91(1): 149-157, 2020 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-32730427

RESUMO

Caustic ingestion represents a serious social-medical problem due to the devastating and irreversible consequences it can produce in the upper digestive tract. In Ibero-America, there are no published reliable data on the incidence or prevalence of caustic-induced injuries, and most of the available information on clinical presentation, diagnosis, treatment, and prognosis is based on retrospective clinical series and, indeed, its clinical management is often based primarily on expert opinion. Re cently as an initiative of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN) and with the cooperation of the Spanish Society for Pediatric Gastroente rology, Hepatology and Nutrition (SEGHNP), we have designed a Clinical Practice Guideline that include a series of statements and recommendations aimed at optimizing patient medical care which is based on the systematic review of evidence. Two (2) successive papers focused on the evaluation of physiopathological and clinical-endoscopic diagnostic features of caustic esophagitis in children (1st. Paper) and, on the other hand, the most relevant therapeutic considerations (2nd. Paper). We expect this guideline to become a useful tool for the physician in the difficult decision-making process when assessing patients after caustic ingestion.


Assuntos
Queimaduras Químicas , Cáusticos/toxicidade , Esofagite , Adolescente , Queimaduras Químicas/diagnóstico , Queimaduras Químicas/etiologia , Queimaduras Químicas/fisiopatologia , Queimaduras Químicas/terapia , Criança , Pré-Escolar , Esofagite/diagnóstico , Esofagite/etiologia , Esofagite/fisiopatologia , Esofagite/terapia , Humanos , Lactente , Pediatria
3.
Rev Chil Pediatr ; 91(2): 289-299, 2020 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-32730551

RESUMO

Caustic ingestion represents a serious social-medical problem due to the devastating and irreversible consequences it can produce in the upper digestive tract. In Ibero-America, there are no published reliable data on the incidence or prevalence of caustic-induced injuries, and most of the available information on clinical presentation, diagnosis, treatment, and prognosis is based on retrospective clinical series and, indeed, its clinical management is often based primarily on expert opinion. Re cently as an initiative of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN) and with the cooperation of the Spanish Society for Pediatric Gastroente rology, Hepatology and Nutrition (SEGHNP), we have designed a Clinical Practice Guideline that include a series of statements and recommendations aimed at optimizing patient medical care which is based on the systematic review of evidence. Two (2) separate papers focused on the evaluation of physiopathological and clinical-endoscopic diagnostic features of caustic esophagitis in children (1st. Paper) and, on the other hand, the most relevant therapeutic considerations (2nd. Paper). We expect this guideline to become a useful tool for the physician in the difficult decision-making process when assessing patients after caustic ingestion.


Assuntos
Queimaduras Químicas/etiologia , Cáusticos/toxicidade , Esofagite/induzido quimicamente , Esôfago/lesões , Queimaduras Químicas/diagnóstico , Queimaduras Químicas/fisiopatologia , Queimaduras Químicas/terapia , Tomada de Decisão Clínica/métodos , Esofagite/diagnóstico , Esofagite/fisiopatologia , Esofagite/terapia , Esôfago/fisiopatologia , Humanos , América Latina , Espanha
4.
Rev. chil. pediatr ; 91(2): 289-299, abr. 2020. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1098904

RESUMO

Resumen: La ingestión de cáusticos representa un grave problema médico-social por las consecuencias devastadoras e irreversibles que puede producir en el tracto digestivo superior. En Iberoamérica no se han publicado datos fidedignos sobre la incidencia o la prevalencia de lesiones inducidas por cáusticos. La información disponible sobre la presentación clínica, diagnóstico, tratamiento y pronóstico se basa en series retrospectivas de casos y, de hecho, su manejo clínico se sustenta en muchos casos fundamentalmente en la opinión de expertos. Recientemente como una iniciativa de la Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición Pediátrica (SLAGHNP) y con la co laboración de colegas de la Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediá trica (SEGHNP), hemos diseñado una Guía de Práctica Clínica (GPC) la cual incluye una serie de enunciados y recomendaciones dirigidos a optimizar la atención a los pacientes y que se basan en la revisión sistemática de la evidencia. En dos (2) manuscritos sucesivos nos hemos enfocado primero, en los aspectos fisiopatológicos y de diagnóstico clínico-endoscópico de la esofagitis cáustica en niños (1a. Parte) y en segundo lugar, en los aspectos más relevantes del tratamiento (2a. Parte). Esperamos esta guía se convierta en una herramienta útil para el clínico en el difícil proceso de toma de decisio nes a la hora de evaluar un paciente posterior a la ingesta de una sustancia cáustica.


Abstract: Caustic ingestion represents a serious social-medical problem due to the devastating and irreversible consequences it can produce in the upper digestive tract. In Ibero-America, there are no published reliable data on the incidence or prevalence of caustic-induced injuries, and most of the available information on clinical presentation, diagnosis, treatment, and prognosis is based on retrospective clinical series and, indeed, its clinical management is often based primarily on expert opinion. Re cently as an initiative of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN) and with the cooperation of the Spanish Society for Pediatric Gastroente rology, Hepatology and Nutrition (SEGHNP), we have designed a Clinical Practice Guideline that include a series of statements and recommendations aimed at optimizing patient medical care which is based on the systematic review of evidence. Two (2) separate papers focused on the evaluation of physiopathological and clinical-endoscopic diagnostic features of caustic esophagitis in children (1st. Paper) and, on the other hand, the most relevant therapeutic considerations (2nd. Paper). We expect this guideline to become a useful tool for the physician in the difficult decision-making process when assessing patients after caustic ingestion.


Assuntos
Humanos , Queimaduras Químicas/etiologia , Cáusticos/toxicidade , Esofagite/induzido quimicamente , Esôfago/lesões , Espanha , Queimaduras Químicas/diagnóstico , Queimaduras Químicas/fisiopatologia , Queimaduras Químicas/terapia , Esofagite/diagnóstico , Esofagite/fisiopatologia , Esofagite/terapia , Esôfago/fisiopatologia , Tomada de Decisão Clínica/métodos , América Latina
5.
Rev. chil. pediatr ; 91(1): 149-157, feb. 2020. tab, graf
Artigo em Espanhol | LILACS, BNUY, UY-BNMED | ID: biblio-1092801

RESUMO

Resumen: La ingestión de cáusticos representa un grave problema médico-social por las consecuencias devastadoras e irreversibles que puede producir en el tracto digestivo superior. En Iberoamérica no se han publicado datos fidedignos sobre la incidencia o la prevalencia de lesiones inducidas por cáusticos. La información disponible sobre la presentación clínica, diagnóstico, tratamiento y pronóstico se basa en series retrospectivas de casos y, de hecho, su manejo clínico se sustenta en muchos casos fundamentalmente en la opinión de expertos. Recientemente como una iniciativa de la Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición Pediátrica (SLAGHNP) y con la co laboración de colegas de la Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediá trica (SEGHNP), hemos diseñado una Guía de Práctica Clínica (GPC) la cual incluye una serie de enunciados y recomendaciones dirigidos a optimizar la atención a los pacientes y que se basan en la revisión sistemática de la evidencia. En dos (2) manuscritos sucesivos nos hemos enfocado primero, en los aspectos fisiopatológicos y de diagnóstico clínico-endoscópico de la esofagitis cáustica en niños (1a. Parte) y en segundo lugar, en los aspectos más relevantes del tratamiento (2a. Parte). Esperamos esta guía se convierta en una herramienta útil para el clínico en el difícil proceso de toma de decisio nes a la hora de evaluar un paciente posterior a la ingesta de una sustancia cáustica.


Abstract: Caustic ingestion represents a serious social-medical problem due to the devastating and irreversible consequences it can produce in the upper digestive tract. In Ibero-America, there are no published reliable data on the incidence or prevalence of caustic-induced injuries, and most of the available information on clinical presentation, diagnosis, treatment, and prognosis is based on retrospective clinical series and, indeed, its clinical management is often based primarily on expert opinion. Re cently as an initiative of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN) and with the cooperation of the Spanish Society for Pediatric Gastroente rology, Hepatology and Nutrition (SEGHNP), we have designed a Clinical Practice Guideline that include a series of statements and recommendations aimed at optimizing patient medical care which is based on the systematic review of evidence. Two (2) successive papers focused on the evaluation of physiopathological and clinical-endoscopic diagnostic features of caustic esophagitis in children (1st. Paper) and, on the other hand, the most relevant therapeutic considerations (2nd. Paper). We expect this guideline to become a useful tool for the physician in the difficult decision-making process when assessing patients after caustic ingestion.


Assuntos
Humanos , Lactente , Pré-Escolar , Criança , Adolescente , Queimaduras Químicas/diagnóstico , Queimaduras Químicas/etiologia , Queimaduras Químicas/fisiopatologia , Queimaduras Químicas/terapia , Cáusticos/toxicidade , Esofagite/diagnóstico , Esofagite/etiologia , Esofagite/fisiopatologia , Esofagite/terapia , Pediatria
7.
J Med Econ ; 19(12): 1207-1214, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27441755

RESUMO

AIMS: To estimate the cost-effectiveness of a new strategy that uses an amino acid formula in the elimination diet of infants with suspected cow's milk allergy (CMA). MATERIALS AND METHODS: This pharmacoeconomic study was developed from the perspective of the Brazilian Public Healthcare System. The new strategy proposes using an amino acid formula in the diagnostic elimination diet of infants (≤24 months) with suspected CMA. The rationale is that infants who do not respond to the amino acid formula do not suffer from CMA. Patients with a positive oral challenge test receive a therapeutic elimination diet based on Brazilian Food Allergy Guidelines. This approach was compared to the current recommendations of the Brazilian Food Allergy Guidelines. A decision model was constructed using TreeAge Pro 2012 software. Model inputs were based on a literature review and the opinions of a panel of experts. A univariate sensitivity analysis of incremental cost-effectiveness ratios was performed. RESULTS: The mean cost per patient of the new amino acid formula strategy was R$3,341.57, while the cost of the current Brazilian guidelines strategy was R$3,641.08. The mean number of symptom-free days per patient, which was used as an indicator of effectiveness, was 900.6 and 875.7 days, respectively. The new strategy is, therefore, dominant. In the sensitivity analysis, the dominance was maintained with parameter variation. LIMITATIONS: In the absence of information in the literature, some premises were defined by a panel of specialists. CONCLUSIONS: The new strategy, which uses an amino acid formula in the elimination diagnostic diet followed by an oral food challenge, is a dominant pharmacoeconomic approach that has a lower cost and results in an increased number of symptom-free days.


Assuntos
Aminoácidos , Técnicas de Diagnóstico do Sistema Digestório/economia , Hipersensibilidade a Leite/diagnóstico , Animais , Brasil , Bovinos , Análise Custo-Benefício , Árvores de Decisões , Farmacoeconomia , Humanos , Lactente , Sensibilidade e Especificidade
9.
Rev Invest Clin ; 66 Suppl 2: S9-S72, 2014 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-25706585

RESUMO

Cow's milk allergy (CMA) is an immune-based disease that has become an increasing problem. The diagnosis and management of CMA varies from one clinical setting to another and represents a challenge in pediatric practice. In addition, because nonallergic food reactions can be confused with CMA symptoms, there is an overdiagnosis of the disease. In response to these situations, pediatric specialties from recognized institutions throughout Latin America decided to develop a clinical guideline for diagnosis and management of cow's milk allergy. These guidelines include definitions, epidemiology, pathophysiology overview, clinical and evidencebased recommendations for the diagnosis and treatment of CMA. They also include prevention and prognosis sections and identify gaps in the current knowledge to be addressed through future research.


Assuntos
Hipersensibilidade a Leite/diagnóstico , Proteínas do Leite/efeitos adversos , Guias de Prática Clínica como Assunto , Medicina Baseada em Evidências , Humanos , América Latina , Hipersensibilidade a Leite/epidemiologia , Hipersensibilidade a Leite/terapia , Proteínas do Leite/imunologia , Prognóstico
10.
J. pediatr. (Rio J.) ; J. pediatr. (Rio J.);89(6): 554-558, nov.-dez. 2013. tab
Artigo em Português | LILACS | ID: lil-697129

RESUMO

OBJETIVO: o ultrassom (US) tem sido uma importante ferramenta de diagnóstico para identificar várias causas de hemorragia gastrointestinal. Neonatos com alergia ao leite de vaca (ALV) podem apresentar hematoquezia, e a confirmação do diagnóstico pode ser difícil. O objetivo deste estudo é descrever achados com ultrassom em escala de cinza e com Doppler colorido em pacientes com ALV. MÉTODOS: estudamos, retrospectivamente, 13 neonatos com ALV. Todos eles apresentaram hematoquezia severa e dor abdominal e foram submetidos a um estudo com US, com o diagnóstico de colite alérgica. O diagnóstico teve como base os achados clínicos, a recuperação após a dieta de exclusão do neonato ou da mãe, no caso de amamentação exclusiva, e o teste de provocação oral positivo. RESULTADOS: a idade média variou de um a seis meses (média = 3,53). Sete dos 13 neonatos (53,8%) passaram novamente por ultrassonografia em escala de cinza e com Doppler colorido após a dieta de exclusão. Dentre eles, 12 dos 13 (92,3%) mostraram anormalidades no US e no ultrassom com Doppler colorido (USDC) no início. Os achados positivos que sugeriram colite foram paredes intestinais espessas e aumento na vascularização, principalmente no cólon descendente e sigmoide. Os resultados da colonoscopia e histopatológicos foram compatíveis com colite alérgica. Após uma mudança na dieta, os 13 neonatos se recuperaram e seus testes de provocação oral foram positivos. CONCLUSÃO: o US com Doppler pode ser muito útil para diagnosticar a colite secundária, como a ALV, e para excluir várias outras doenças abdominais que podem imitar essa doença.


OBJECTIVE: ultrasound (US) has been an important diagnostic tool to identify several causes of gastrointestinal bleeding. Infants with cow's milk allergy (CMA) may present hematochezia and the confirmation of the diagnosis can be difficult. The aim of this study is to describe grayscale and color Doppler ultrasound findings in patients with CMA. METHODS: we retrospectively studied 13 infants with CMA. All infants presented severe hematochezia and abdominal pain. All underwent an US study with the diagnosis of allergic colitis. This diagnosis was based on clinical findings, recovery after infant or mother exclusion diets in the case of exclusive breastfeeding and positive oral challenge test. RESULTS: the mean age ranged from 1 to 6 months (mean = 3.53). Seven out of 13 infants (53.8%) had grayscale and color Doppler sonographic repeated after exclusion diet. Twelve out of 13 (92,3%) showed abnormalities at US and CDUS at beginning. The positive findings suggesting colitis were thickened bowel walls and increased vascularity, especially in the descending and sigmoid colon. Colonoscopy and histopathological findings were compatible with allergic colitis. After a diet change the 13 infants recovered and their oral challenge tests were positive. CONCLUSION: Doppler US may be very useful in diagnosing secondary colitis, such as CMA, and to exclude several other abdominal diseases that can emulate this disease.


Assuntos
Feminino , Humanos , Lactente , Masculino , Dor Abdominal , Hemorragia Gastrointestinal , Hipersensibilidade a Leite/diagnóstico , Proctocolite/diagnóstico , Colite/etiologia , Colite , Hemorragia Gastrointestinal/dietoterapia , Hemorragia Gastrointestinal/etiologia , Hipersensibilidade a Leite/dietoterapia , Proctocolite/imunologia , Estudos Retrospectivos , Resultado do Tratamento , Ultrassonografia Doppler em Cores
11.
J Pediatr (Rio J) ; 89(6): 554-8, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24035877

RESUMO

OBJECTIVE: ultrasound (US) has been an important diagnostic tool to identify several causes of gastrointestinal bleeding. Infants with cow's milk allergy (CMA) may present hematochezia and the confirmation of the diagnosis can be difficult. The aim of this study is to describe grayscale and color Doppler ultrasound findings in patients with CMA. METHODS: we retrospectively studied 13 infants with CMA. All infants presented severe hematochezia and abdominal pain. All underwent an US study with the diagnosis of allergic colitis. This diagnosis was based on clinical findings, recovery after infant or mother exclusion diets in the case of exclusive breastfeeding and positive oral challenge test. RESULTS: the mean age ranged from 1 to 6 months (mean=3.53). Seven out of 13 infants (53.8%) had grayscale and color Doppler sonographic repeated after exclusion diet. Twelve out of 13 (92,3%) showed abnormalities at US and CDUS at beginning. The positive findings suggesting colitis were thickened bowel walls and increased vascularity, especially in the descending and sigmoid colon. Colonoscopy and histopathological findings were compatible with allergic colitis. After a diet change the 13 infants recovered and their oral challenge tests were positive. CONCLUSION: Doppler US may be very useful in diagnosing secondary colitis, such as CMA, and to exclude several other abdominal diseases that can emulate this disease.


Assuntos
Dor Abdominal/diagnóstico por imagem , Hemorragia Gastrointestinal/diagnóstico por imagem , Hipersensibilidade a Leite/diagnóstico , Proctocolite/diagnóstico , Colite/diagnóstico por imagem , Colite/etiologia , Feminino , Hemorragia Gastrointestinal/dietoterapia , Hemorragia Gastrointestinal/etiologia , Humanos , Lactente , Masculino , Hipersensibilidade a Leite/dietoterapia , Proctocolite/imunologia , Estudos Retrospectivos , Resultado do Tratamento , Ultrassonografia Doppler em Cores
12.
Rev. argent. salud publica ; 4(16): 31-38, set. 2013. tab
Artigo em Espanhol | LILACS | ID: lil-767332

RESUMO

INTRODUCCIÓN: No existe evidencia de que la conformación de redes de atención y procesos de mejora de la calidad en Argentina se relacionen con mejores resultados en el tratamiento del infarto agudo de miocardio. OBJETIVOS: Evaluar las principales causas de demora o no reperfusión en pacientes con infarto agudo de miocardio y supradesnivel del ST, determinando si la conformación de redes de atención, derivación precoz y mejora de la calidad produce mejores resultados. MÉTODOS: Se realizó un análisis de línea de base, con registro inicial de pacientes en seis centros. En aquellos pacientes que no recibieron tratamiento apropiado (demora o falta de reperfusión), se analizaron las causas raíz. En cada centro se implementaron intervenciones ajustadas a estas causas. En la segunda fase del registro se evaluaron los resultados de las intervenciones. RESULTADOS: En la primera etapa del registro se incluyó a 193 pacientes. El primer lugar de recepción fueron las guardias externas (55,4%), seguidas de las ambulancias (25,9%). Un total de 81 pacientes (41,2%) no recibieron un tratamiento apropiado. Las principales causas fueron el desconocimiento de los pacientes y las demoras en el traslado y diagnóstico. Una vez implementadas las intervenciones, en la segunda etapa (con 226 pacientes) la proporción con demora o sin tratamiento adecuado se redujo al 32,3% (n=73,p=0,04). CONCLUSIONES: Fue factible identificar las principales causas de demora en el tratamiento del infarto agudo de miocardio con supradesnivel del ST e implementar redes de atención y ciclos de mejora. Esto puede mejorar los resultados de la reperfusión, que tiene un gran impacto en la mortalidad.


INTRODUCTION: There is no evidence that networking for care and quality improvement process in Argentina brings better results in the treatment of acute myocardial infarction. OBJECTIVES: To assess the main causes of delay or non-reperfusion in patients with acute myocardial infarction and elevated ST segment, determining whether the networking for care, early referral and quality improvement brings better results. METHODS: A base lineanalysis was performed, including initial patient records in six centers. For those patients who had not received appropriate treatment (delay or lack of reperfusion), root causes were explored. Case-related interventions were implemented in each center. The second stage of the record assessed intervention results. RESULTS: The first stage of the record included 193 patients. The first place of reception were emergency departments (55.4 percent), followed by ambulances (25.9 percent). A total of 81 patients (41.2 percent) did not receive appropriate treatment. This was mainly due to lack of information about patients and delays for transfer and diagnosis. In the second stage (with 226 patients), after the implementation of interventions, the rate with delay or without appropriate treatment was reduced to 32.3 percent (n=73, p=0.04). CONCLUSIONS: It was possible to identify the main causes of delay in the treatment of acute myocardial infarction with elevated ST segment, and to implement networks for care and improvement cycles. This can improve reperfusion results, which have a big impact on mortality.


Assuntos
Humanos , Estudos de Avaliação como Assunto , Qualidade da Assistência à Saúde , Diagnóstico Tardio , Infarto do Miocárdio/diagnóstico , Infarto do Miocárdio/terapia , Falha de Tratamento , Reperfusão Miocárdica/mortalidade , Reperfusão Miocárdica/reabilitação , Tempo para o Tratamento , Transferência de Pacientes , Argentina
13.
Clin Nutr ; 32(1): 93-7, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22841400

RESUMO

BACKGROUND & AIMS: To determine the relevance of waist circumference (WC) measurement and monitoring in children and adolescents as an early indicator of overweight, metabolic syndrome (MS) and cardiovascular problems in young adults in comparison with visceral and subcutaneous adiposity. METHODS: A cohort study with 159 subjects (51.6% female) started in 1999 with an average age of 13.2 years. In 1999, 2006 and 2008 weight, height, and WC were evaluated. In 2006 blood samples for laboratory diagnosis of MS were added. In 2008 abdominal computed tomography (ACT) to quantify the fat deposits were also added. RESULTS: The WC measured in children and adolescents was strongly correlated with body mass index (BMI) measured simultaneously. A strong correlation was established between WC in 1999 with measures of WC and BMI as young adults. WC strongly correlated with fat deposits in ACT. The WC in 1999 expressed more subcutaneous fat (SAT), while the WC when young adults expressed strong correlation with both visceral fat (VAT) and SAT. The correlation of WC with fat deposits was stronger in females. WC and not BMI in 1999 was significantly higher in the group that evolved to MS. CONCLUSIONS: The WC in children and adolescents was useful in screening patients for MS. WC expressed the accumulation of abdominal fat; especially subcutaneous fat.


Assuntos
Adipogenia , Adiposidade , Desenvolvimento do Adolescente , Desenvolvimento Infantil , Síndrome Metabólica/diagnóstico , Obesidade/complicações , Sobrepeso/complicações , Adolescente , Índice de Massa Corporal , Brasil , Criança , Estudos de Coortes , Diagnóstico Precoce , Feminino , Humanos , Gordura Intra-Abdominal/diagnóstico por imagem , Gordura Intra-Abdominal/patologia , Estudos Longitudinais , Masculino , Síndrome Metabólica/sangue , Síndrome Metabólica/complicações , Síndrome Metabólica/patologia , Obesidade/diagnóstico por imagem , Sobrepeso/diagnóstico por imagem , Caracteres Sexuais , Gordura Subcutânea Abdominal/diagnóstico por imagem , Gordura Subcutânea Abdominal/patologia , Tomografia Computadorizada por Raios X , Circunferência da Cintura
15.
Pediatr Radiol ; 42(12): 1465-70, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22956178

RESUMO

BACKGROUND: Blood flow volume in the superior mesenteric artery (SMA) measured by pulsed Doppler has been used in adults to evaluate Crohn disease but has not been utilized in children and adolescents. OBJECTIVE: To establish a cutoff point for normal SMA blood flow using pulsed Doppler US measurement in healthy children and adolescents. MATERIALS AND METHODS: The study included healthy volunteers from an urban community, divided into two age groups, children (5-9 years) and adolescents (10-17 years). Anthropometric measurements included waist circumference and body surface area classified according to the z-score of body mass index. Heart rate, blood pressure, oxygen saturation and temperature were measured immediately before US evaluation. RESULTS: The average age of the 60 participants was 12.2 years. Of these, 21 (35%) were ages 5-9 years and 39 (65%) were ages 10-17 years; 21 (35%) were boys. Findings of the two examiners coincided for 58 of the 60 (96.7%) participants. SMA blood flow was significantly lower in the children (mean ± SD = 556 ± 122 ml/min) than in adolescents (mean ± SD 775 ± 311 ml/min) (P < 0.001). SMA blood flow showed statistically significant positive associations with body surface area. CONCLUSION: We found that superior mesenteric artery blood flow is significantly lower in children than in adolescents and is associated with body surface area.


Assuntos
Determinação do Volume Sanguíneo/métodos , Artéria Mesentérica Superior/diagnóstico por imagem , Artéria Mesentérica Superior/fisiologia , Ultrassonografia Doppler Dupla/métodos , Adolescente , Velocidade do Fluxo Sanguíneo/fisiologia , Volume Sanguíneo/fisiologia , Criança , Feminino , Humanos , Masculino , Valores de Referência , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Adulto Jovem
16.
Radiol. bras ; Radiol. bras;44(4): 268-270, jul.-ago. 2011. ilus
Artigo em Português | LILACS | ID: lil-598557

RESUMO

O divertículo de Meckel é a anomalia congênita mais comum do trato gastrintestinal e a hemorragia é a complicação mais frequente. Cintilografia, ultrassonografia modo B e com Doppler, e tomografia computadorizada podem ser utilizadas para detectar complicações. Descrevemos dois casos de divertículo de Meckel complicado detectados à ultrassonografia, cujos achados foram diferentes dos descritos na literatura.


Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract and bleeding is its most frequent complication. Scintigraphy, B-mode and Doppler ultrasonography, and computed tomography may be utilized to detect complications. The present report describes two cases of complicated Meckel's diverticulum detected at ultrasonography whose findings were different from those described in the literature.


Assuntos
Humanos , Masculino , Pré-Escolar , Adolescente , Diverticulite , Divertículo Ileal , Diagnóstico por Imagem , Ultrassonografia Doppler em Cores
17.
AJR Am J Roentgenol ; 196(6): W817-22, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21606275

RESUMO

OBJECTIVE: The objective of our study was to evaluate whether gray-scale and color Doppler ultrasound can reveal intestinal inflammation in infants with cow's milk allergy (CMA). SUBJECTS AND METHODS: This study evaluated the clinical findings and grayscale and color Doppler sonograms of 34 infants. Seventeen 0- to 6-month-old infants with suspected CMA and 17 nonsymptomatic age-matched infants were evaluated by a blinded investigator who determined the percentage of vessel density and the thickness of different parts of the bowel. Clinical and sonographic variables were evaluated in the same regions of bowel considering three time points: presentation, after 4 weeks of feeding only amino acid-based formula, and after challenge test. Likelihood ratios and receiver operating characteristic (ROC) curves were used to define a cutoff point for vascular density percentage. RESULTS: The difference in the percentage of vessel density between patients with CMA (mean, 28.1%) and control infants (mean, 7.77%) was statistically significant. ROC analysis showed that a cutoff point of 18.7% could differentiate between patients with CMA and control infants with 81.8% sensitivity and 94.1% specificity. The area under the curve was 0.941. We found statistical differences in bowel wall thickness between control patients and patients with CMA. CONCLUSION: There was a significant increase in vessel density in infants younger than 6 months with CMA compared with healthy age-matched infants. The most appropriate cutoff point for vessel density was 18.7%. The results of this study suggest that Doppler ultrasound could be used as a screening tool to diagnose CMA.


Assuntos
Intestinos/diagnóstico por imagem , Hipersensibilidade a Leite/diagnóstico por imagem , Ultrassonografia Doppler em Cores , Área Sob a Curva , Estudos de Casos e Controles , Feminino , Humanos , Lactente , Recém-Nascido , Inflamação/diagnóstico por imagem , Masculino , Exame Físico , Estudos Prospectivos , Curva ROC , Sensibilidade e Especificidade , Inquéritos e Questionários
18.
BMC Pediatr ; 10: 25, 2010 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-20416046

RESUMO

BACKGROUND: Cow's milk is the most common food allergen in infants and the diagnosis of cow's milk allergy is difficult, even with the use of several diagnostic tests. Therefore, elimination diets and challenge tests are essential for the diagnosis and treatment of this disorder. The aim of this study is to report the clinical presentation and nutritional status of children evaluated by pediatric gastroenterologists for the assessment of symptoms suggestive of cow's milk allergy. METHODS: An observational cross-sectional study was performed among 9,478 patients evaluated by 30 pediatric gastroenterologists for 40 days in 5 different geographical regions in Brazil. Clinical data were collected from patients with symptoms suggestive of cow's milk allergy. The nutritional status of infants (age < or = 24 months) seen for the first time was evaluated according to z-scores for weight-for-age, weight-for-height, and height-for-age. Epi-Info (CDC-NCHS, 2000) software was used to calculate z-scores. RESULTS: The prevalence of suspected cow's milk allergy in the study population was 5.4% (513/9,478), and the incidence was 2.2% (211/9,478). Among 159 infants seen at first evaluation, 15.1% presented with a low weight-for-age z score (< -2.0 standard deviation - SD), 8.7% with a low weight-for-height z score (< -2.0 SD), and 23.9% with a low height-for-age z score (< -2.0 SD). CONCLUSION: The high prevalence of nutritional deficits among infants with symptoms suggestive of cow's milk allergy indicates that effective elimination diets should be prescribed to control allergy symptoms and to prevent or treat malnutrition.


Assuntos
Desnutrição/etiologia , Hipersensibilidade a Leite/complicações , Hipersensibilidade a Leite/diagnóstico , Leite/efeitos adversos , Estado Nutricional , Fatores Etários , Animais , Estatura , Peso Corporal , Brasil/epidemiologia , Bovinos , Estudos Transversais , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Masculino , Leite/imunologia , Hipersensibilidade a Leite/epidemiologia , Hipersensibilidade a Leite/fisiopatologia , Prevalência
19.
Rev. bras. nutr. clín ; 24(3): 155-158, jul.-set. 2009. tab
Artigo em Português | LILACS | ID: lil-550230

RESUMO

Objetivo: Comparar os registros de diarréia em pacientes adultos internados, submetidos á nutrição enteral (NE), antes e após treinamento da equipe de enfermagem. Método: Foram avaliados os registros de diarréia realizados pelas equipes de enfermagem, para estes pacientes, durante 30 dias em dois momentos, antes (G1) e após (G2) treinamento, que constava de definição de diarréia (pelo menos 3 fezes líquidas ou semi-líquidas por dia), imagens de evacuações e mudança na forma de registro, com padronização das anotações (o número de evacuações e a quantidade estimada). o intervalo entre as coletas foi de um ano. Resultados: No G1 foram observados 40 pacientes (71+- 17 anos; 52,5% homens), com registro de diarréia em 15 pacientes; 1,66 +- 3,2 dias de diarréia/paciente. com base na definição acima, 10/15 apresentaram efetivamente diarréia. os técnicos descreveram 65 dias com diarréia, mas utilizando a definição padronizada, ocorreu em apenas 18 dias. No G2 foram avaliados 37 pacientes (75,8 +- 13,3 anos; 54,1%homens). foram relatados 0,08 +- 0,27 dias de diarréia/paciente. no G1, o número de dias efetivos de diarréia foi maior que no G2, mas sem diferença estatística. a única diferença estatisticamente significativa foi entre os dias efetivos de diarréia entre os dois grupos (p=0,001). Conclusão: os autores demonstram que a padronização de registros e treinamento da equipe contribuiu para a redução de diagnósticos equiviocados de diarréia.


Objective: To compare the records of diarrhea in hospitalized adult patients, undergoing enteral nutrition (EN), before and after training of nursing staff. Methods: We studied the records of diarrhea made by nursing staff for these patients during 30 days on two occasions, before (G1) and after (G2) training, which included the definition of diarrhea (at least 3 liquid stools or semi net-a day), images of evacuations and change in registration form, with standardization of the notes (the number of bowel movements and estimated). the interval between collections was one year. Results: In G1 were observed 40 patients (71 + - 17 years, 52.5% men) with a record of diarrhea in 15 patients, 1.66 + - 3.2 days of diarrhea / patient. based on the above definition, 10/15 had actually diarrhea. technicians reported 65 days with diarrhea, but using the standard definition, occurred in only 18 days. G2 were assessed 37 patients (75.8 + - 13.3 years, 54.1% men). reported were 0.08 + - 0.27 days of diarrhea / patient. in G1, the actual number of days of diarrhea was higher than in G2, but no statistical difference. the only difference was statistically significant between the actual days of diarrhea between the two groups (p = 0.001). Conclusion: The authors show that the standardization of records and staff training contributed to the reduction of diagnostic equiviocados diarrhea.


Objetivo: Comparar los registros de la diarrea en pacientes adultos hospitalizados, con nutrición enteral (NE), antes y después del entrenamiento del personal de enfermería. Métodos: Se estudiaron los registros de la diarrea por parte del personal de enfermería para estos pacientes durante 30 días en dos ocasiones, antes de (G1) y después (G2) la formación, que incluía la definición de diarrea (heces líquidas por lo menos 3 o semi Net-a-día), las imágenes de las evacuaciones y el cambio en el formulario de inscripción, con la normalización de las notas (el número de evacuaciones intestinales y estimadas). el intervalo entre las colecciones era un año. Resultados: En el G1 se observaron 40 pacientes (71 + - 17 años, hombres 52,5%) con un registro de la diarrea en 15 pacientes, 1.66 + - 3,2 días de diarrea / paciente. sobre la base de la definición anterior, 10/15 había hecho diarrea. técnicos informaron 65 días con diarrea, pero utilizando la definición estándar, se produjo en sólo 18 días. G2 se evaluaron 37 pacientes (75,8 + - 13,3 años, 54,1% hombres). se reportaron 0,08 + - 0,27 días de diarrea / paciente. en el G1, el número real de días de diarrea fue superior en el G2, pero sin diferencia estadística. la única diferencia fue estadísticamente significativa entre los días reales de la diarrea entre los dos grupos (p = 0,001). Conclusión: Los autores demuestran que la normalización de los registros y la capacitación del personal contribuido a la reducción de la diarrea equiviocados diagnóstico.


Assuntos
Humanos , Masculino , Idoso , Diarreia/diagnóstico , Diarreia/enfermagem , Equipe de Enfermagem/organização & administração , Nutrição Enteral/enfermagem , Nutrição Enteral , Enfermagem Primária/métodos , Enfermagem Primária
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