RESUMO
A case of ganglioneuroma of parapharyngeal space is described and the literature on this field is briefly reviewed. The patient, a 7-year-old female, presented with a left parapharyngeal space mass causing medial displacement of the left lateral pharyngeal wall. The lesion sized 4.4 cm in the largest diameter. Histologically, the tumour showed the coexistence of two distinct cells types--ganglion cells and Schwann cells--within a loose stroma. Immunohistochemically, both cell types were immunoreactive for S-100 protein and negative for cytokeratins.
Assuntos
Ganglioneuroma/patologia , Neoplasias de Cabeça e Pescoço/patologia , Biomarcadores Tumorais/análise , Criança , Feminino , Ganglioneuroma/química , Ganglioneuroma/cirurgia , Proteína Glial Fibrilar Ácida/análise , Neoplasias de Cabeça e Pescoço/química , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Proteínas de Neoplasias/análise , Proteínas S100/análise , Células de Schwann/patologia , Vimentina/análiseRESUMO
The authors describe a case of lymphoepithelioma-like carcinoma (LELC) of the esophagus occurring in a 77-year-old man. To date, 13 cases have been described in the literature, all in natives of Japan. Histological features, immunohistochemical findings and differential diagnosis are discussed. In our case epithelial neoplastic cells were completely negative for the EBV genome.