MAS and MANS Predicts Repeated Sprint Ability in Youth Soccer Players.

The study investigated the impact of maximal aerobic speed (MAS) and maximal anaerobic sprint (MANS) on repeated sprint ability (RSA) in soccer. METHODS: 17 amateur-to semi-professional soccer players, age 19 (± 4) years, were tested for maximal oxygen consumption (VO2max), oxygen cost of running (Cr), RSA consisting of 15·20m sprint each divided by a 100 seconds dribble track, and 40-meter sprint performance. MAS was calculated as VO2max · Cr-1, and MANS was defined as the highest velocity in the 40-meter sprint. RESULTS: There was a strong correlation between MAS and average 20-meter RSA velocity (r = 0.760; p < 0.01), and between MAS and performance decrement (r = -0.648; p < 0.01). The product of 0.5MAS + 0.5MANS exhibited the strongest correlation with RSA (r = 0.813; p < 0.01). CONCLUSION: The combination of MAS and MANS strongly predicted RSA. High-intensity aerobic interval training (HIIT) and maximal strength training (MST) are recommended to improve MAS and MANS, and could thus lead to better RSA on the soccer field.

Maximal aerobic and anaerobic power and time performance in 800 m double poling ergometer.

The purpose of this study was to investigate to what extent aerobic power (MAP), maximal anaerobic power (MANP), anaerobic capacity measured as time to exhaustion at 130% MAP (TTE), and maximal accumulated oxygen deficit (MAOD) correlated with 800 m double poling time trial performance (800TT) in a ski ergometer. A second aim was to investigate the relationship between TTE and MAOD, and to what extent TTE and MAOD would relate to anaerobic power reserve (APR). Eighteen cross-country skiers were tested for peak oxygen uptake (VO2peak) and oxygen cost of double poling to assess MAP. Peak power measurements during a 100 m TT were performed to assess MANP. TTE and an 800TT with continuous VO2 measurements were performed to assess time performance and MAOD. All tests were performed on a ski ergometer. Both MAP and MANP correlated strongly (r = - 0.936 and - 0.922, respectively, p < 0.01) with 800TT. Neither TTE nor MAOD correlated with 800TT. TTE correlated moderately with MAOD, both in mL kg-1 and in %VO2peak (r = 0.559, p < 0.05 and 0.621, p < 0.01, respectively). Both TTE and MAOD seemed to be a product of APR. These results suggest focusing on MAP and MANP, but not anaerobic capacity to explain time performance in an event with approximately 3 min duration.

Relationships Between Maximal Aerobic Speed, Lactate Threshold, and Double Poling Velocity at Lactate Threshold in Cross-Country Skiers.

Purpose: To investigate the relationships between maximal aerobic speed (MAS), lactate threshold in per cent of peak oxygen uptake (LT) and velocity at LT (LTv) in cross-country skiers. Secondly, we aimed to explore the fit of an equation previously used in cyclists and runners in a cohort of well-trained, competitive cross-country skiers for calculation of LTv. Thirdly, we aimed to investigate if a new LTv could still be calculated after a period of regular training only by providing a new MAS. Methods: Ninety-five competitive cross-country skiers (65 males and 30 females) were tested for maximal oxygen uptake (VO2max), peak oxygen uptake in double poling (DP-VO2peak), oxygen cost of double poling (CDP), LT, and LTv. Thirty-five skiers volunteered to be tested 3 months later to evaluate potential changes in LT and LTv. Results: Velocity at LT was mainly determined by MAS (r = 0.88, p < 0.01). LT did not show a significant impact on LTv. The product of MAS·LT precisely predicted LTv at baseline (r = 0.99, SEE = 2.4%), and by only measuring MAS, a new LTv could be accurately calculated (r = 0.92, SEE = 6.8%) 3 months later in a sub-set of the initial 95 skiers (n = 35). Conclusion: The results suggest that LT has minor impact on LTv in DP tested in a laboratory. LTv seemed to be predominantly determined by MAS, and we suggest to put more focus on MAS and less on LT and LTv in regular testing to evaluate aerobic performance capacity in DP.

Effect of aerobic exercise intensity on health-related quality of life in severe obesity: a randomized controlled trial.

BACKGROUND: Aerobic exercise is an important part of obesity treatment and may improve health-related quality of life (HRQOL). The objective of this study was to compare the effect of two different exercise programs on health-related quality of life in patients with severe obesity. METHODS: This was a single-center, open-label, randomized, parallel-group study comparing the effects of a 24-week moderate-intensity continuous training (MICT) program and a combined high-intensity interval training program with MICT (HIIT/MICT). The primary objective (specified secondary outcome) was to assess HRQOL by using the general health dimension of the Short Form Health Survey (SF-36). The secondary objectives were to assess other dimensional SF-36 scores, the impact of weight on the physical and psychosocial aspects of quality of life (IWQOL-Lite), and the burden of obesity-specific weight symptoms (WRSM). RESULTS: 73 patients were enrolled and reported patient reported outcome measures, with 71 patients (55% females) allocated to either MICT (n = 34) or HIIT/MICT (n = 37). In the intention-to-treat analysis, general health scores increased between baseline and 24-week follow-up in both the HIIT/MICT group and the MICT group, with a mean change of 13 (95% CI 6-21) points and 11 (95% CI 5-17) points, respectively, with no difference between the groups. The effect sizes of these changes were moderate. The vitality and social functioning scores of SF-36, and the physical function and self-esteem scores of IWQOL-Lite increased moderately in both groups, with no difference between groups. The tiredness, back pain, and physical stamina scores based on WRSM showed moderate to strong changes in both the groups. CONCLUSIONS: Patients who had completed a combined HIIT/MICT program did not experience larger improvements in general health compared with those completing a clean 24-week MICT program. Exercise may confer general health benefits independent of intensity. TRIALS REGISTRATION: Regional Committees for Medical and Health Research Ethics south east, Norway, October 23, 2013 (identifier: 2013/1849) and ClinicalTrials.gov December 8, 2014 (identifier: NCT02311738).

Effects of Individual Changes in Training Distribution on Maximal Aerobic Capacity in Well-Trained Cross-Country Skiers: A Follow-Up Study.

The purpose of this study was to evaluate individual changes in training distribution and the subsequent effects on maximal oxygen uptake (VO2max). The participants were well-trained cross-country skiers who had performed a year with no substantial changes in training prior to this study. Six cross-country skiers, who were participants in a larger previous study, volunteered for a follow-up study. All skiers performed self-motivated changes in training distribution for a new preparation period in this follow-up, generally by more high-intensity training (HIT). All training characteristics were registered from training diaries. During the follow-up period, all skiers performed an incremental VO2max test in February 2020 and August 2020. Training were categorized into three different training periods; (1) February 2019 to February 2020 (P 1) representing the training performed prior to the follow-up, (2) February 2020 to July 2020 (P 2), and (3) July 2020 to August 2020 (P 3). On average, the skiers increased their VO2max by 5.8 ± 5.0% (range: -1.8 to + 10.2%) during the follow-up study compared with the average VO2max during the preceding year. Total training volume increased on average by 10.0 and 25.7% in P 2 and P 3, respectively, compared with P 1. The average volume of HIT was similar between P 1 and P 2 but increased 62.8% in P 3. However, large individual differences in training changes were observed. In conclusion, the present study revealed that individual changes in training distribution generated an increased VO2max in four out of six already well-trained cross-country skiers. Reduced total training volume (three out of six) and increased (four out of six) HIT volume were the most marked changes.

Aerobic and Anaerobic Speed Predicts 800-m Running Performance in Young Recreational Runners.

The main aim was to investigate the impact of maximal aerobic speed (MAS), maximal anaerobic speed (MANS), and time to exhaustion (TTE) at 130% MAS, on 800-m running time performance (800TT). A second aim was to investigate the impact of anaerobic speed reserve (ASR), i.e., the relative difference between MAS and MANS, on TTE. A total of 22 healthy students classified as recreational runners participated in a cross-sectional study. They were tested for maximal oxygen consumption (VO2max), oxygen cost of running (CR), time performance at 100 m (100TT), time performance at 800 m (800TT), and TTE. MAS was calculated as VO2max × CR -1, and MANS was calculated as 100TT velocity. Both MAS and MANS correlated individually with 800TT (r = -0.74 and -0.67, respectively, p < 0.01), and the product of MAS and MANS correlated strongly (r = -0.82, p < 0.01) with 800TT. TTE did not correlate with 800TT. Both ASR and % MANS correlated strongly with TTE (r = 0.90 and -0.90, respectively, p < 0.01). These results showed that 800TT was first and foremost dependent on MAS and MANS, and with no impact from TTE. It seemed that TTE was merely a product of each runner's individual ASR. We suggest a simplified model of testing and training for 800TT, namely, by focusing on VO2max, CR, and short sprint velocity, i.e., MAS and MANS.

Responses to Maximal Strength Training in Different Age and Gender Groups.

PURPOSE: The present study aimed to investigate the potential impact of age, gender, baseline strength, and selected candidate polymorphisms on maximal strength training (MST) adaptations. METHODS: A total of 49 subjects (22 men and 27 women) aged 20-76 years, divided into five age groups, completed an 8 weeks MST intervention. Each MST session consisted of 4 sets with 4 repetitions at ∼85-90% of one-repetition maximum (1RM) intensity in leg-press, three times per week. 1RM was tested pre and post the intervention and blood samples were drawn to genotype candidate polymorphisms ACE I/D (rs1799752), ACTN3 R577X (rs1815739), and PPARGC1A Gly482Ser (rs8192678). RESULTS: All age groups increased leg-press 1RM (p < 0.01), with a mean improvement of 24.2 ± 14.0%. There were no differences in improvements between the five age groups or between male and female participants, and there were no non-responders. Baseline strength status did not correlate with 1RM improvements. PPARGC1A rs8192678 T allele carriers had a 15% higher age- and gender corrected baseline 1RM than the CC genotype (p < 0.05). C allele carriers improved 1RM (%) by 34.2% more than homozygotes for the T allele (p < 0.05). CONCLUSION: To the best of our knowledge, this is the first study to report improvement in leg-press maximal strength regardless of gender, baseline strength status in all age groups. The present study is also first to demonstrate an association between the PPARGC1A rs8192678 and maximal strength and its trainability in a moderately trained cohort. MST may be beneficial for good health and performance of all healthy individuals.

Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity-A Randomized Controlled Trial.

OBJECTIVE: This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure. METHODS: This was a single-center randomized controlled trial of patients with severe obesity allocated to a 24-week moderate-intensity continuous training (MICT) program or a combined MICT with high-intensity interval training (HIIT/MICT) program. The primary outcome was energy expenditure during exercise (EEDE). Secondary outcomes included resting metabolic rate, cardiorespiratory fitness, and body composition. RESULTS: A total of 82 (56% females) patients were screened, and 71 (55% females) patients were allocated to HIIT/MICT (n = 37) or MICT (n = 34). Per-protocol analysis showed that EEDE increased by 10% (95% CI: 3%-17%) in the HIIT/MICT group (n = 16) and 7.5% (95% CI: 4%-10%) in the MICT group (n = 24), with no differences between groups. In the 8- to 16- week per-protocol analysis, the HIIT/MICT group had a significantly larger increase in EEDE compared with the MICT group. Resting metabolic rate remained unchanged in both groups. HIIT/MICT and MICT were associated with significant weight loss of 5 kg and 2 kg, respectively. CONCLUSIONS: Patients completing a 24-week combined HIIT/MICT program did not achieve a higher EEDE compared with those who completed a 24-week MICT program. The HIIT/MICT group experienced, on average, a 3-kg-larger weight loss than the MICT group.

Steeper or Faster? Tactical Dispositions to Minimize Oxygen Cost in Ski Mountaineering.

PURPOSE: Investigate the effect of speed, inclination, and use of heel elevator on the oxygen cost of vertical climbing (Cvert) in ski mountaineering. METHODS: In this study, 19 participants who were (3 women and 16 men) moderate- to well-trained recreational Norwegian ski mountaineers were involved. All participants were tested for VO2max in running, and in a ski mountaineering test on a treadmill, to assess Cvert. The test protocol consisted of 12 4 min work periods at different inclinations from 13 to 23°, with continuous VO2 measurements. After every second work period, the inclination increased by 2°, and speed was decreased accordingly. The speed reduction was based on the equation Vvert = speed · sin(α), where α represents the angle of inclination. Vvert was thus held constant for each work period (854 m·h-1). All work periods were completed twice, with and without a heel elevator. Half of the subjects started with the smallest inclination, and the other half started with the steepest inclination. RESULTS: The results showed that Cvert was unchanged at all inclinations except 13°, where there was a significantly higher Cvert, at the same Vvert. Only at 13°, Cvert was higher with the use of heel elevator. There was also a significant trend indicating lower Cvert with use of heel elevator with steeper inclination. CONCLUSIONS: There seemed to be nothing to gain by choosing detours if the inclination was 13° or less. The use of heel elevator was more advantageous, the steeper the inclination, but at 13° there was a negative effect of using heel elevator.

Improving Utilization of Maximal Oxygen Uptake and Work Economy in Recreational Cross-Country Skiers With High-Intensity Double-Poling Intervals.

PURPOSE: To investigate the effect of a double-poling (DP) high-intensity aerobic interval-training (HIT) intervention performed without increasing total HIT volume. This means that regular HIT training (eg, running) was replaced by HIT DP. The aim was to explore whether this intervention could improve peak oxygen uptake in DP, the fractional utilization of maximal oxygen uptake (VO2max) in DP, oxygen cost of DP, maximal aerobic speed, and a 3-km DP time trial. METHODS: Nine non-specially-DP-trained cross-country skiers (intervention group) and 9 national-level cross-country skiers (control group) were recruited. All participants were tested for VO2max in running, peak oxygen uptake in DP, oxygen cost of DP, and time-trial performance before and after a 6-wk, 3-times-per-week HIT DP intervention. The intervention group omitted all regular HIT with HIT in DP, leaving the total weekly amount of HIT unchanged. RESULTS: Seven participants in each group completed the study. VO2max in running remained unchanged in both groups, whereas peak oxygen uptake in DP improved by 7.1% (P = .005) in the intervention group. The fractional utilization of VO2max in DP thus increased by 7.3% (P = .019), oxygen cost of DP by 9.2% (P = .047), maximal aerobic speed by 16.5% (P = .009), and time trial by 19.5% (P = .004) in the intervention group but remained unchanged in the control group. CONCLUSIONS: The results indicate that a 6-wk HIT DP intervention could be an effective model to improve DP-specific capacities, with maintenance of VO2max in running.

No Change - No Gain; The Effect of Age, Sex, Selected Genes and Training on Physiological and Performance Adaptations in Cross-Country Skiing.

The aim was to investigate the effect of training, sex, age and selected genes on physiological and performance variables and adaptations before, and during 6 months of training in well-trained cross-country skiers. National-level cross-country skiers were recruited for a 6 months observational study (pre - post 1 - post 2 test). All participants were tested in an outside double poling time trial (TTDP), maximal oxygen uptake in running (RUN-VO2max), peak oxygen uptake in double poling (DP-VO2peak), lactate threshold (LT) and oxygen cost of double poling (CDP), jump height and maximal strength (1RM) in half squat and pull-down. Blood samples were drawn to genetically screen the participants for the ACTN3 R577X, ACE I/D, PPARGC1A rs8192678, PPARG rs1801282, PPARA rs4253778, ACSL1 rs6552828, and IL6 rs1474347 polymorphisms. The skiers were instructed to train according to their own training programs and report all training in training diaries based on heart rate measures from May to October. 29 skiers completed all testing and registered their training sufficiently throughout the study period. At pre-test, significant sex and age differences were observed in TTDP (p < 0.01), DP-VO2peak (p < 0.01), CDP (p < 0.05), MAS (p < 0.01), LTv (p < 0.01), 1RM half squat (p < 0.01), and 1RM pull-down (p < 0.01). For sex, there was also a significant difference in RUN-VO2max (p < 0.01). No major differences were detected in physiological or performance variables based on genotypes. Total training volume ranged from 357.5 to 1056.8 min per week between participants, with a training intensity distribution of 90-5-5% in low-, moderate- and high-intensity training, respectively. Total training volume and ski-specific training increased significantly (p < 0.05) throughout the study period for the whole group, while the training intensity distribution was maintained. No physiological or performance variables improved during the 6 months of training for the whole group. No differences were observed in training progression or training adaptation between sexes or age-groups. In conclusion, sex and age affected physiological and performance variables, with only a minor impact from selected genes, at baseline. However, minor to no effect of sex, age, selected genes or the participants training were shown on training adaptations. Increased total training volume did not affect physiological and performance variables.

Factors Influencing Running Velocity at Lactate Threshold in Male and Female Runners at Different Levels of Performance.

BACKGROUND: The primary aim was to examine the relationship between lactate threshold (LT) expressed as percentage of maximal oxygen uptake (VO2max) and running velocity at LT (LTV). A secondary aim was to investigate to what extent VO2max, oxygen cost of running (CR), and maximal aerobic speed (MAS) determined LTV. A third aim was to investigate potential differences in LT and LTV between elite, national and recreational runners, as well as possible gender differences regarding VO2max, CR, LT, and LTV. METHODS: Seventy-five competitive runners (37 males and 38 females) with an average VO2max of 63.0 ± 9.3 mL⋅kg-1⋅min-1, and an average LTV of 13.6 ± 2.3 km⋅h-1 were tested for VO2max, LT, LTV, MAS, and CR. RESULTS: Lactate threshold did not correlate with LTV. With an r - value of 0.95 (p < 0.001) and a standard error of estimate of 4.0%, the product of MAS and individual LT determined 90% of LTV, outside a range of ±0.27 km⋅h-1. LTV increased with higher performance level. However, LT did not differ between elite, national and recreational runners. Female runners had 2.5% higher LT, 8% lower LTV, and 21% lower VO2max, but 9% better CR than male runners. CONCLUSION: Lactate threshold did not correlate with LTV. The product of MAS and LT correlated strongly with LTV. There were no differences between elite, national and recreational runners regarding LT, but female runners had higher LT than the male runners. Female runners at the same relative performance level had lower LTV and VO2max, but better CR than male runners.

Large Inter-Individual Differences in Responses to a Block of High Intensity Aerobic Interval Training: A Case Series in National-level Cyclists and Triathletes.

The aim was to investigate individual responses on VO2max and performance to a block of high intensity aerobic interval training (HIIT) in national-level endurance athletes. METHODS: National-level cyclists and triathletes (five men and two women, 31 ± 3.3 years, VO2max 65.1 ± 3.3 ml·kg-1·min-1) conducted 14 HIIT sessions (4×4 min uphill running at 90-95% maximal heart rate) in nine days during preseason. VO2max in running and cycling, lactate threshold (LT) in cycling, oxygen cost of cycling (CC), and a cycling time-trial (TT) were tested two days pre and seven days post intervention. Feasibility was determined using attendance rates, adherence (defined as completing all sessions), and reported adverse events. RESULTS: The results showed that adherence was 100% with 100% attendance rate. No adverse events were reported. TT (-75.6 ± 50.8 seconds, p < 0.0001) but not VO2max cycling (-0.2 ± 4.6 ml×kg-1×min-1, p = 0.53) or running (0.2 ± 1.2 ml×kg-1×min-1, p = 0.85) was improved on group level. The individual responses varied from -8.2% to +14.5% change in VO2max, and -7.5% to +0.8% in TT. CONCLUSIONS: The large inter-individual differences in responses call for tailor-making HIIT blocks, mapping of biomarkers to avoid overtraining, and studying the effects of such blocks with longer follow-up than seven days.

Distribution of allele frequencies for genes associated with physical activity and/or physical capacity in a homogenous Norwegian cohort- a cross-sectional study.

BACKGROUND: There are large individual differences in physical activity (PA) behavior as well as trainability of physical capacity. Heritability studies have shown that genes may have as much impact on exercise participation behavior as environmental factors. Genes that favor both trainability and participation may increase the levels of PA. The present study aimed to assess the allele frequencies in genes associated with PA and/or physical capacity, and to see if there is any association between these polymorphisms and self-reported PA levels in a cohort of middle-aged Norwegians of Scandinavian descent (n = 831; mean age mean age (± SD) 55.5 ± 3.8 years). RESULTS: The genotype distributions of the ACTN3 R577X, ACE I/D and MAOA uVNTR polymorphisms were similar to other populations of European descent. When comparing the genotype distribution between the low/medium level PA group (LMPA) and high level PA groups (HPA), a significant difference in ACTN3 577X allele distribution was found. The X allele frequency was 10% lower in the HPA level group (P = 0.006). There were no differences in the genotype distribution of the ACE I/D or MAOA uVNTR polymorphism. Education and previous participation in sports or outdoor activities was positively associated with the self-reported PA levels (P ≤ 0.001). CONCLUSIONS: To the best of our knowledge, this is the first study to report association between ACTN3 R577X genotype and PA level in middle-aged Scandinavians. Nevertheless, the contribution of a single polymorphism to a complex trait, like PA level, is likely small. Socioeconomic variables, as education and previous participation in sports or outdoor activities, are positively associated with the self-reported PA levels.

Stronger Is Better: The Impact of Upper Body Strength in Double Poling Performance.

The purpose of the present study was to compare time results from a roller-skiing double poling (DP) time trial with different physiological variables, muscular strength variables, and DP characteristics in both male and female young competitive skiers with the same relative training background. In order to do this, 28 (16 women and 12 men) well-trained 16-25-year-old cross-country skiers from three Norwegian high schools for skiers, as well as local high performance competitive skiers from the South-East of Norway were recruited to participate in the study. All participants were tested for; maximal oxygen uptake in running, Peak oxygen uptake in DP, lactate threshold in DP, DP economy, time to voluntary exhaustion in DP, force analyses in DP, one repetition maximum and power output in pulldown, and leg press and a time trial during DP roller skiing. The results expressed strong correlations between roller skiing time trial performance and maximal strength in pull-down, both independent (r xy = -0.83, p < 0.01) and dependent (r xy-z = -0.50, p < 0.02) of sex. Higher maximal upper body strength was related to higher DP peak forces (PF) (r xy = 0.78, p < 0.02), lower DP frequency (r xy = -0.71, p < 0.01), and shorter DP contact time (CT) (r xy = -0.48, p < 0.02). The practical implications of the present study is to acknowledge maximal upper body strength as a performance determining factor in DP. This point at the importance of including maximal strength training in cross-country skiers training programs.

Associations between cardiorespiratory fitness and weight loss in patients with severe obesity undergoing an intensive lifestyle intervention program: retrospective cohort study.

BACKGROUND: To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program. METHODS: Retrospective cohort study conducted at a tertiary care outpatient rehabilitation center from November 1, 2013 through January 1, 2017. CRF was measured as maximal oxygen consumption during a maximal oxygen uptake (VO2max) test on a treadmill or bicycle at baseline and after 3 months. RESULTS: A total of 180 patients had a baseline mean (SD) BMI 41.1 (4.8) kg/m2 and CRF of 79.4 (14.9) mL·kg-0.75·min- 1. Patients with a baseline CRF above median achieved a greater 3-month and 1-year weight loss compared with patients with CRF below median; mean (95% CI) 2.5 kg (1.3, 3.8) and 4.0 kg (0.8, 7.2), respectively. In addition, patients with 3-month changes of CRF above median had 4.0 kg (0.9, 7.1) greater weight loss at 1-year follow-up than those below median. CONCLUSIONS: Among patients with severe obesity who underwent a 1-year ILI program, higher baseline CRF was associated with significantly larger weight loss after 3 months and 1 year. In addition, those with higher initial 3-month CRF changes had greater weight loss at 1 year. TRIAL REGISTRATION: Retrospectively registered in Regional Committees for Medical and Health Research Ethics (REC) south east September 22, 2016 (2016/1414) and clinicaltials.gov August 13, 2018 (identifier: NCT03593798 ).

High-intensity aerobic interval training improves aerobic fitness and HbA1c among persons diagnosed with type 2 diabetes.

PURPOSE: It remains to be established how high-intensity aerobic interval training (HAIT) affects risk factors associated with type 2 diabetes (TD2). This study investigated effects of HAIT on maximal oxygen uptake (VO2max), glycated Hemoglobin type A1C (HbA1c), insulin resistance (IR), fat oxidation (FatOx), body weight (BW), percent body fat (%BF), lactate threshold (LT), blood pressure (BP), and blood lipid profile (BLP) among persons with T2D. Results were compared to the effects after a moderate-intensity training (MIT) program. METHODS: Thirty-eight individuals with T2D completed 12 weeks of supervised training. HAIT consisted of 4 × 4 min of walking or running uphill at 85-95% of maximal heart rate, and MIT consisted of continuous walking at 70-75% of maximal heart rate. RESULTS: A 21% increase in VO2max (from 25.6 to 30.9 ml kg-1 min-1, p < 0.001), and a reduction in HbA1c by -0.58% points (from 7.78 to 7.20%, p < 0.001) was found in HAIT. BW and body mass index (BMI) was reduced by 1.9% (p < 0.01). There was a tendency towards an improved FatOx at 60% VO2max (14%, p = 0.065). These improvements were significant different from MIT. Both HAIT and MIT increased velocity at LT, and reduced %BF, waist circumference, hip circumference, and BP, with no significant differences between the two groups. Correlations were found between change in VO2max and change in HbA1c when the two intervention groups were combined (R = -0.52, p < 0.01). CONCLUSION: HAIT is an effective exercise strategy to improve aerobic fitness and reduce risk factors associated with T2D.