RESUMO
Occupational bronchial asthma with its prevalence amounting to 14% is one of the main entities in occupational morbidity structure. Clinical evidence in recent decades demonstrates changed phenotype of occupational bronchial asthma. Changes are increased number of patients suffering from the severe asthma, higher occurrence of occupational bronchial asthma which pathogenesis is more significantly mediated by nonimmune mechanisms. Prevalence of these types of occupational bronchial asthma approaches 9.7-22%.
Assuntos
Adenilil Ciclases/sangue , Asma/sangue , Doenças Profissionais/sangue , Asma/enzimologia , Asma/fisiopatologia , AMP Cíclico/sangue , GMP Cíclico/sangue , Humanos , Hidrocortisona/sangue , Sistema Hipotálamo-Hipofisário/fisiopatologia , Infecções/complicações , Pessoa de Meia-Idade , Doenças Profissionais/enzimologia , Doenças Profissionais/fisiopatologia , Sistema Hipófise-Suprarrenal/fisiopatologiaRESUMO
Workers engaged into treatment of nonferrous alloys are exposed to aerosols of condensation and disintegration. Those who contact aerosols of nonferrous metals demonstrate respiratory, gastrointestinal and skin diseases. To reveal a role of occupational factors in formation of those diseases, the authors designed diagnostic criteria according to results of clinical, allergologic, immunologic and cytochemical studies.