RESUMO
Acute alcohol intoxication in rats with alloxan diabetes is accompanied by the increase of urea and uric acid and by the decrease in free fatty acids in serum. In the liver of experimental animals the increase of activity of glutamate dehydrogenase, AMP deaminase, and tyrosine transaminase was found.
Assuntos
Intoxicação Alcoólica/metabolismo , Diabetes Mellitus Experimental/metabolismo , Fígado/metabolismo , Nitrogênio/metabolismo , AMP Desaminase/sangue , Intoxicação Alcoólica/complicações , Aminoácidos/sangue , Aminoácidos/metabolismo , Animais , Glutamato Desidrogenase/metabolismo , Glutaminase/sangue , Masculino , Ratos , Tirosina Transaminase/sangue , Ureia/sangue , Ácido Úrico/sangueRESUMO
Hypoglycemic coma induced by administration of a large dose of insulin, was accompanied by the increased rates of glycolysis, glycogenolysis, activity of lactate dehydrogenase, succinate dehydrogenase, isocitrate dehydrogenase, and increased concentration of glycogen. Under these conditions triacylglycerol content decreased administration of the large dose of insulin to rats with alloxan diabetes increased not only rates of glycolysis, glycogenolysis and lactate dehydrogenase activity and also activities of aspartate transaminase and glutamate dehydrogenase. Data obtained suggest the increased utilization of amino acids for energy supply of myocardium under conditions of hypoglycemia induced by insulin adminisration to diabetic animals.
