RESUMO
In order to study the mechanisms of development of pathological changes in children living in contaminated areas and chronically exposed to radionuclides as a result of exposure through the food chain, studied the vegetative homeostasis and thermographic study endothelium-dependent vascular reactions with occlusive tests. Showed signs of dysregulation of the autonomic nervous system dysfunction, the secretory activity of the endothelium and increased secretion of substances endothelial origin.
Assuntos
Sistema Nervoso Autônomo/efeitos da radiação , Acidente Nuclear de Chernobyl , Endotélio Vascular/efeitos da radiação , Frequência Cardíaca/efeitos dos fármacos , Homeostase/efeitos da radiação , Vasodilatação/efeitos da radiação , Adolescente , Estudos de Casos e Controles , Criança , Eletrocardiografia , Endotélio Vascular/inervação , Humanos , Termografia , UcrâniaRESUMO
The children--residents of contaminated territories, born from mothers irradiated in their childhood had in remote period of the Chernobyl Disaster an increase in the frequency of disorders connected with immune system activation and depressive types, increase in intensity of free radical processes in blood serum and erythrocytes.
Assuntos
Radicais Livres/sangue , Imunidade Celular/efeitos da radiação , Imunidade Humoral/efeitos da radiação , Exposição Materna/efeitos adversos , Exposição Paterna/efeitos adversos , Poluentes Radioativos/toxicidade , Estudos de Casos e Controles , Acidente Nuclear de Chernobyl , Criança , Eritrócitos/metabolismo , Eritrócitos/efeitos da radiação , Feminino , Granulócitos/efeitos da radiação , Humanos , Masculino , Fagocitose/efeitos da radiação , Gravidez , Fatores de Tempo , UcrâniaRESUMO
Children who live in radiation polluted areas have been found with the help of cytochemical analysis of enzymatic spectrum of circulating lymphocytes to have less active energy creation processes taken place in mitochondrions. It is partially compensated by intensification of glycolytic reactions and involvement of lipids and amino acids in processes of energy creation. These changes on system level (the muscle system) were confirmed by electromyography. It is confirmed showing the decrease in bioelectrical activity and functional reserves of muscle tissue and clinically by signs of chronic fatigue signs.
