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1.
JBJS Case Connect ; 9(2): e0124, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31188794

RESUMO

CASE: Total hip arthroplasty (THA) is a commonly performed surgery with well-known complications. Unreported in the literature is a displaced meniscus tear in the acute postoperative period. We present the case of a displaced meniscus tear acutely after THA and discuss our management of this unique problem. CONCLUSIONS: Displaced meniscus tears after THA pose unique challenges and should be considered in patients with knee pain after THA. Arthroscopic intervention occurred 8 weeks after THA to minimize prosthetic joint dislocation and loosening during arthroscopy.


Assuntos
Artroplastia de Quadril/efeitos adversos , Artroscopia/métodos , Lesões do Menisco Tibial/cirurgia , Adulto , Assistência ao Convalescente , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/patologia , Imageamento por Ressonância Magnética/métodos , Masculino , Dor/etiologia , Período Pós-Operatório , Radiografia/métodos , Amplitude de Movimento Articular/fisiologia , Lesões do Menisco Tibial/diagnóstico por imagem , Lesões do Menisco Tibial/patologia , Resultado do Tratamento
2.
Foot Ankle Int ; 37(9): 919-23, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27287343

RESUMO

BACKGROUND: Electromagnetic bone growth stimulators have been found to biologically enhance the bone healing environment, with upregulation of numerous growth factors. The purpose of the study was to quantify the effect, in vivo, of pulsed electromagnetic fields (PEMFs) on growth factor expression and healing time in fifth metatarsal nonunions. METHODS: This was a prospective, randomized, double-blind trial of patients, cared for by 2 fellowship-trained orthopedic foot and ankle surgeons. Inclusion criteria consisted of patients between 18 and 75 years old who had been diagnosed with a fifth metatarsal delayed or nonunion, with no progressive signs of healing for a minimum of 3 months. Eight patients met inclusion criteria and were randomized to receive either an active stimulation or placebo PEMF device. Each patient then underwent an open biopsy of the fracture site and was fitted with the appropriate PEMF device. The biopsy was analyzed for messenger-ribonucleic acid (mRNA) levels using quantitative competitive reverse transcription polymerase chain reaction (QT-RT-PCR). Three weeks later, the patient underwent repeat biopsy and open reduction and internal fixation of the nonunion site. The patients were followed at 2- to 4-week intervals with serial radiographs and were graded by the number of cortices of healing. RESULTS: All fractures healed, with an average time to complete radiographic union of 14.7 weeks and 8.9 weeks for the inactive and active PEMF groups, respectively. A significant increase in placental growth factor (PIGF) level was found after active PEMF treatment (P = .043). Other factors trended higher following active PEMF including brain-derived neurotrophic factor (BDNF), bone morphogenetic protein (BMP) -7, and BMP-5. CONCLUSION: The adjunctive use of PEMF for fifth metatarsal fracture nonunions produced a significant increase in local placental growth factor. PEMF also produced trends toward higher levels of multiple other factors and faster average time to radiographic union compared to unstimulated controls. LEVEL OF EVIDENCE: Level I, prospective randomized trial.


Assuntos
Proteína Morfogenética Óssea 5/fisiologia , Proteína Morfogenética Óssea 7/fisiologia , Fator Neurotrófico Derivado do Encéfalo/fisiologia , Traumatismos do Pé/fisiopatologia , Consolidação da Fratura/fisiologia , Fraturas Ósseas/fisiopatologia , Ossos do Metatarso/fisiopatologia , Proteína Morfogenética Óssea 5/química , Proteína Morfogenética Óssea 5/metabolismo , Proteína Morfogenética Óssea 7/química , Proteína Morfogenética Óssea 7/metabolismo , Método Duplo-Cego , Campos Eletromagnéticos , Humanos , Ossos do Metatarso/patologia , Ossos do Metatarso/fisiologia , Avaliação de Resultados em Cuidados de Saúde , Estudos Prospectivos , Fator de Crescimento Transformador beta
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