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Rev Sci Instrum ; 92(8): 084710, 2021 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-34470408

RESUMO

An insulated-gate bipolar transistor (IGBT) pulse generator for repetitive transcranial magnetic stimulation used for in vivo laboratory experiments on small animals, such as mice, is reported. The pulse generator is based upon an IGBT that can switch 700 A of current for 1 ms and that has a DC breakdown voltage of 1200 V. The duration of the design's output pulse is controlled by, and follows, an input trigger pulse. The voltage amplitude of the output pulses is determined by an external high-voltage power supply and the energy stored in a 330 µF capacitor bank. The approach enables the amplitude of the voltage applied across the coil, the length of time the voltage is applied, and the number of times the voltage pulses are applied all to be controlled and adjusted to facilitate a wide range of experimental options. This paper provides a detailed schematic of the design, design discussions, and some representative experimental results. Additionally, the reported design can be scaled to higher currents by using an IGBT with a higher current rating.


Assuntos
Laboratórios , Estimulação Magnética Transcraniana , Animais , Fontes de Energia Elétrica , Camundongos , Fenômenos Físicos
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