RESUMO
OBJECTIVE: To evaluate the circumstances in which recurrent laryngeal nerve palsy occurs after thyroid surgery. METHODS: This study assessed 1026 patients who underwent surgery for benign thyroid disease over a seven-year period in a retrospective, single-centre study. RESULTS: With a total of 1835 recurrent laryngeal nerves at risk, there were 38 cases (2.07 per cent) of transient recurrent laryngeal nerve palsy and 8 (0.44 per cent) of permanent recurrent laryngeal nerve palsy. No explanation was found for 10 of the 46 cases of recurrent laryngeal nerve palsy. Among the 38 other cases, the probable causes included poor identification of the recurrent laryngeal nerve during surgery, involuntary resection of the nerve and several other factors. CONCLUSION: Apart from accidental resection of the recurrent laryngeal nerve during thyroid surgery, the causes of post-operative recurrent laryngeal nerve palsy are often unclear and likely multifactorial. Poor identification of the recurrent laryngeal nerve during surgery is still the main cause of post-operative recurrent laryngeal nerve palsy, even when intra-operative neuromonitoring is used.
Assuntos
Complicações Pós-Operatórias/epidemiologia , Doenças da Glândula Tireoide/cirurgia , Tireoidectomia , Paralisia das Pregas Vocais/epidemiologia , Adenoma/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Bócio Nodular/cirurgia , Doença de Graves/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Traumatismos do Nervo Laríngeo Recorrente/epidemiologia , Estudos Retrospectivos , Neoplasias da Glândula Tireoide/cirurgia , Nódulo da Glândula Tireoide/cirurgia , Tireoidite/cirurgia , Adulto JovemRESUMO
OBJECTIVES: To assess the role of cardiovascular risk factors, intake of drugs altering hemostasis and severity signs in patients admitted with spontaneous epistaxis. MATERIAL AND METHODS: A single-center retrospective study covering a 7-year period in a university hospital center included 205 patients admitted with spontaneous epistaxis. Study variables comprised: cardiovascular risk factors (cardiovascular disease or history of cardiovascular disease with hemorrhagic or thromboembolic risk, high blood pressure, type-2 diabetes, dyslipidemia), intake of drugs altering hemostasis, blood pressure and minimum hemoglobin level during hospital stay. Groups of serious and non-serious epistaxis were distinguished. RESULTS: There were no significant inter-group differences for mean age, sex ratio, history of high blood pressure or number of cardiovascular risk factors. Serious epistaxis was associated with significantly lower blood pressure and hemoglobinemia. Number of cardiovascular risk factors correlated with probability of blood transfusion. CONCLUSION: The real influence of the various study factors, including severity factors, on onset of spontaneous epistaxis remains to be elucidated.
Assuntos
Doenças Cardiovasculares/complicações , Doenças Cardiovasculares/diagnóstico , Epistaxe/etiologia , Hospitais Universitários , Pacientes Internados , Idoso , Índice de Massa Corporal , Doenças Cardiovasculares/terapia , Diabetes Mellitus Tipo 2/complicações , Feminino , Transtornos Hemorrágicos/complicações , Humanos , Hipertensão/complicações , Tempo de Internação , Masculino , Estudos Retrospectivos , Fatores de Risco , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
OBJECTIVE: To determine whether pre-operative serum 25-hydroxyvitamin D has an impact on post-operative parathyroid hormone and serum calcium levels in patients undergoing total thyroidectomy for benign goitre. METHODS: This single-centre, retrospective study comprised 246 unselected surgical patients who had undergone total thyroidectomy for bilateral, benign, multinodular goitre. The correlation between pre-operative serum 25-hydroxyvitamin D and post-operative serum parathyroid hormone and serum calcium was studied to determine whether low pre-operative serum 25-hydroxyvitamin D was predictive of post-operative hypocalcaemia. RESULTS: Seventy-nine patients (32 per cent) had post-operative hypocalcaemia. Eighteen patients (7.32 per cent) experienced unintentional parathyroidectomy (1 parathyroid gland in 15 patients, 2 parathyroid glands in 3 patients). In univariate analysis, pre-operative serum 25-hydroxyvitamin D was not correlated with post-operative serum calcium (p = 0.69) or post-operative serum parathyroid hormone (p = 0.5804). Furthermore, in multivariate analysis, which took into account unintentional parathyroidectomy, no correlation was found (p = 0.33). Bilateral unintentional parathyroidectomy was statistically associated with post-operative hypocalcaemia (p = 0.032). CONCLUSION: Pre-operative serum 25-hydroxyvitamin D did not appear to have any impact on post-operative serum calcium in patients undergoing total thyroidectomy for benign goitre.
Assuntos
Cálcio/sangue , Bócio Nodular/cirurgia , Hipocalcemia/sangue , Vitamina D/análogos & derivados , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Bócio Nodular/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Paratireoidectomia/métodos , Estudos Retrospectivos , Tireoidectomia/métodos , Resultado do Tratamento , Vitamina D/sangue , Adulto JovemRESUMO
OBJECTIVE: To evaluate the presence of cardiovascular risk factors and recovery of idiopathic sudden sensorineural hearing loss in hospitalised patients. METHODS: A single-centre retrospective study of 80 patients hospitalised for idiopathic sudden sensorineural hearing loss was conducted over a 6-year period. Mean pure tone hearing thresholds were assessed by pure tone audiometry. RESULTS: Twenty-three of 80 patients (28.75 per cent) initially had no cardiovascular risk factors. Forty-five patients had hyperlipidaemia, 22 patients had hypertension, 7 patients had diabetes mellitus and 7 patients were obese. No statistically significant difference was observed between patients with complete versus partial sudden sensorineural hearing loss (p = 0.0708) concerning the cardiovascular risk factors. At long-term follow up, the hearing recovery rate was not significantly different between the two groups of patients (p = 0.7541). CONCLUSION: The lack of a clear relationship between idiopathic sudden sensorineural hearing loss and cardiovascular risk factors suggests that sudden sensorineural hearing loss has a predominantly multifactorial disease profile regardless of hearing impairment severity.
Assuntos
Doenças Cardiovasculares/epidemiologia , Perda Auditiva Neurossensorial/diagnóstico , Perda Auditiva Súbita/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Audiometria de Tons Puros , Feminino , Perda Auditiva Neurossensorial/complicações , Perda Auditiva Súbita/complicações , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Recuperação de Função Fisiológica , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento , Adulto JovemRESUMO
OBJECTIVES: To determine whether intra-operative neuromonitoring (IONM) of the vagus nerve during thyroidectomy can predict postoperative vocal fold palsy. DESIGN: A single-centre, prospective study. SETTING: University Hospital. PARTICIPANTS: A total of 95 patients underwent thyroid surgery. A total of 160 vagus nerves were studied. The amplitude of the action potential of vocal muscles was recorded intra-operatively by indirect supramaximal stimulation of the vagus nerve. All patients underwent flexible fibre-optic laryngoscopy on postoperative day 1 to detect the presence of vocal fold palsy. MAIN OUTCOME MEASURES: The primary outcome measure was the difference of the action potential amplitude of the vagus nerve before and after resection of the thyroid lobe. Statistical analysis determined the amplitude variation cut-off able to accurately predict postoperative vocal fold palsy. RESULTS: Transient vocal fold palsy was observed in 4.375% of cases, and permanent fold palsy was observed in 1.25% of cases. A decrease of the action potential amplitude by more than 61% was statistically significantly associated with postoperative vocal fold palsy. A greater than 87% decrease of the amplitude of the action potential was correlated with permanent postoperative vocal fold palsy. CONCLUSION: IONM of the vagus nerve during thyroidectomy may accurately predict postoperative vocal fold palsy.
Assuntos
Monitorização Intraoperatória/métodos , Complicações Pós-Operatórias/epidemiologia , Tireoidectomia , Nervo Vago , Paralisia das Pregas Vocais/epidemiologia , Adulto , Idoso , Feminino , Humanos , Laringoscopia , Masculino , Pessoa de Meia-Idade , Estudos ProspectivosRESUMO
OBJECTIVES: The present study sought to determine whether there is a correlation between the prevalence of superior semicircular canal (SSC) dehiscence (SSCD) on temporal CT and population age. The secondary objective was to identify anatomic factors for SSCD by studying SSC diameter and its protrusion into the middle cranial fossa. The aim was to determine the acquired or congenital origin of SSCD (Minor's syndrome). MATERIAL AND METHOD: A single-center retrospective radiological and anatomic study included 180 CT scans of 354 petrous parts of the temporal bone taken between January and December 2011 in a university hospital center. Bone thickness above the SSC was measured and classified in 4 grades: grade 1, >2.5mm; grade 2, <2.5mm: grade 3, predehiscent; grade 4, dehiscent. SSC diameter was also measured, as was the height of SSC protrusion into the middle cranial fossa. RESULTS: SSCD was found in 0.8% of cases and predehiscence in 12%. Patients with dehiscence were older; patients with grade 3 or 4 were significantly older than those free of dehiscence (P<0.05). There was no significant difference in SSC diameter according to grade. In grade 1, protrusion was greater than in other subjects, with a significant correlation between age and reduced protrusion (P<0.05). CONCLUSION: The study demonstrated a correlation between aging and SSCD prevalence. Reduced SSC roof height with age suggests that SSCD may be an acquired phenomenon, related in some way to aging of the base of the skull.
Assuntos
Doenças do Labirinto/diagnóstico por imagem , Canais Semicirculares/anatomia & histologia , Canais Semicirculares/diagnóstico por imagem , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Doenças do Labirinto/epidemiologia , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Síndrome , Adulto JovemRESUMO
OBJECTIVE: This study aimed to evaluate the impact of intra-operative neuromonitoring of the recurrent laryngeal nerve during total thyroidectomy for benign goitre. METHODS: A single-centre retrospective study using historical controls was conducted for a 10-year period, comprising a series of 767 patients treated by total thyroidectomy for benign goitre. Of these, 306 had intra-operative neuromonitoring of the recurrent laryngeal nerve and 461 did not. Post-operative laryngeal mobility was assessed in all patients by direct laryngoscopy before hospital discharge and at post-operative follow-up visits. RESULTS: In all, 6 out of 461 patients (1.30 per cent) in the control group and 6 out of 306 patients (1.96 per cent) in the intra-operative neuromonitoring group developed permanent recurrent laryngeal nerve palsy. No statistically significant difference was observed between the two patient groups. CONCLUSION: Intra-operative neuromonitoring does not appear to affect the post-operative recurrent laryngeal nerve palsy rate or to reliably predict post-operative recurrent laryngeal nerve palsy. However, it can accurately predict good nerve function after thyroidectomy.
Assuntos
Bócio/cirurgia , Laringoscopia/métodos , Monitorização Intraoperatória/métodos , Traumatismos do Nervo Laríngeo Recorrente/prevenção & controle , Nervo Laríngeo Recorrente/fisiologia , Tireoidectomia/métodos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Traumatismos do Nervo Laríngeo Recorrente/fisiopatologia , Estudos Retrospectivos , Fatores de TempoRESUMO
OBJECTIVE: The study was designed to assess the prevalence, management and survival of patients with simultaneous squamous cell carcinomas of the oral cavity and hypopharynx (OC/HP). MATERIAL AND METHODS: A multicenter, retrospective study (2 university hospitals) was conducted between 2003 and 2007 on a series of 96 patients with simultaneous squamous cell cancers of the OC/HP. RESULTS: A total of 88 men and 8 women were included in the study: 81 patients presented double sites, 14 presented triple sites and one presented quadruple sites. The tumour sites most frequently observed were: hypopharynx in 61% of cases (involving the pyriform sinus in 42% of cases) and the oropharynx in 59% of cases (involving the palatine tonsil in 30% of cases). Upper aerodigestive tract endoscopy under general anaesthesia revealed a simultaneous lesion not suspected on clinical examination in 45% of patients: the site discovered on endoscopy was hypopharyngeal in 2 out of 3 cases; the tumour was classified T1 or T2 in 95.5% of cases. Patients treated simultaneously for all sites had a better prognosis than patients in whom each tumour was treated separately. The 5-year specific survival was 34% and the 5-year overall survival was 28%. CONCLUSION: The prevalence of simultaneous squamous cell carcinomas of the oral cavity and hypopharynx ranges between 1 to 7.4% in the literature and was 4.6% in the present series. A common treatment strategy for each of the patient's tumours appears to be superior to the current theoretical approach that consists of considering each tumour separately.
Assuntos
Carcinoma de Células Escamosas/mortalidade , Carcinoma de Células Escamosas/terapia , Neoplasias Hipofaríngeas/mortalidade , Neoplasias Hipofaríngeas/terapia , Neoplasias Bucais/mortalidade , Neoplasias Bucais/terapia , Neoplasias Primárias Múltiplas/mortalidade , Neoplasias Primárias Múltiplas/terapia , Adulto , Idoso , Carcinoma de Células Escamosas/patologia , Terapia Combinada , Endoscopia , Feminino , Humanos , Neoplasias Hipofaríngeas/patologia , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/patologia , Neoplasias Primárias Múltiplas/patologia , Cuidados Paliativos , Estudos RetrospectivosRESUMO
OBJECTIVES: To compare postoperative complication rates after dissection tonsillectomy in patients operated by outpatient surgery and patients operated by inpatient surgery. POPULATION AND METHODS: A prospective, single-centre, observational study was conducted over a period of 1 year. Dissection tonsillectomy was performed in 103 patients (mean age: 4 years) between September 2011 and September 2012. The following parameters were studied: bleeding or inflammatory complication rate, readmissions, unscheduled visits, factors contraindicating outpatient surgery, reasons for failure of outpatient surgery and influence of Postoperative Nausea and Vomiting scores. RESULTS: Two patient groups were composed: 54 patients were managed by outpatient surgery (Group O) and 49 patients were managed by inpatient surgery (Group I). The two main factors contraindicating outpatient surgery were age less than 3 years (40%) and preoperative suspicion of sleep apnoea-hypopnoea syndrome (26%). Seven patients of Group O had to stay in hospital (outpatient failure rate of 13%). Postoperative complications were observed in 13% of patients of Group O versus 12.2% of patients of Group I with no statistically significant difference between the two groups. One patient in each group had to be readmitted; no statistically significant difference was observed between the two groups (P=0.41). PONV scores were very high (2) in all cases. CONCLUSION: Outpatient tonsillectomy in well-selected patients is not associated with a higher postoperative complication rate than inpatient tonsillectomy. With systematic appropriate prophylaxis, Postoperative Nausea and Vomiting scores had no influence on the postoperative course.
Assuntos
Procedimentos Cirúrgicos Ambulatórios , Hospitalização , Complicações Pós-Operatórias/epidemiologia , Tonsilectomia , Criança , Pré-Escolar , Feminino , França/epidemiologia , Humanos , Masculino , Readmissão do Paciente , Seleção de Pacientes , Estudos ProspectivosRESUMO
OBJECTIVE: The authors present the guidelines of the French Society of Oto-Rhino-Laryngology and Head and Neck Surgery (SFORL) on patient information ahead of thyroid surgery. METHODS: A multidisciplinary medical team was tasked with a scientific literature review on this topic. The texts retrieved were analyzed by an independent committee. A joint meeting drew up the final guidelines. The strength of the recommendations (grade A, B or C) was based on levels of evidence. RESULTS: It is recommended that the results of preoperative exploration and the indications for surgery should be explained to the patient. Patients should be informed as to the type of surgery, surgical objectives, risks and consequences. It is mandatory to obtain the patient's written consent before surgery. CONCLUSION: Appropriate medical information is a critical step in patient management.
Assuntos
Educação de Pacientes como Assunto , Tireoidectomia , Anestesia Geral , França , Humanos , Consentimento Livre e Esclarecido/legislação & jurisprudência , Equipe de Assistência ao Paciente , Direitos do Paciente/legislação & jurisprudência , Cuidados Pós-Operatórios , Complicações Pós-Operatórias , Cuidados Pré-OperatóriosRESUMO
OBJECTIVES: To study the morbidity of central compartment dissection in differentiated thyroid carcinoma of the follicular epithelium. MATERIAL AND METHOD: A retrospective study of 83 patients (61 patients operated by total thyroidectomy and 22 patients operated by total thyroidectomy and central dissection) was performed. Postoperative serum calcium and laryngeal mobility were studied and statistically compared (Chi(2) test, Fisher's exact test). RESULTS: No significant difference was observed between the two groups in terms of the incidence of recurrent laryngeal nerve paralysis or permanent hypoparathyroidism. In contrast, transient hypoparathyroidism was more frequent among patients undergoing thyroidectomy associated with central dissection (P=0.02). CONCLUSION: Central compartment dissection associated with total thyroidectomy does not increase the risk of recurrent laryngeal nerve paralysis or permanent hypoparathyroidism, but is responsible for an increased rate of transient hypoparathyroidism.
Assuntos
Adenocarcinoma Folicular/cirurgia , Carcinoma Papilar/cirurgia , Dissecação/métodos , Hipoparatireoidismo/etiologia , Complicações Pós-Operatórias/etiologia , Neoplasias da Glândula Tireoide/cirurgia , Tireoidectomia/métodos , Paralisia das Pregas Vocais/etiologia , Adenocarcinoma Folicular/sangue , Adenocarcinoma Folicular/patologia , Adulto , Idoso , Cálcio/sangue , Carcinoma Papilar/sangue , Carcinoma Papilar/patologia , Feminino , Seguimentos , Humanos , Laringoscopia , Excisão de Linfonodo/métodos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Complicações Pós-Operatórias/sangue , Estudos Retrospectivos , Risco , Neoplasias da Glândula Tireoide/patologiaRESUMO
PURPOSE OF THE STUDY: The principal objective is to evaluate the circumstances of diagnosis and the treatment of cervical cellulitis and descending mediastinitis. MATERIAL AND METHOD: It is about a retrospective study concerning ten patients, hospitalized between January 2000 and July 2011 in the University Hospital of Amiens for cervical cellulitis and descending mediastinitis, included according to Estrera's criterion. RESULTS: The starting point was oropharyngeal (tonsillitis) in 70% of the cases. The three main germs were Streptococcus spp, Streptococcus milleri and Prevotella spp. The diffusion of the infection was done mainly by retropharyngeal way. 70% presented a mediastinitis associated to cellulitis. All the patients were operated by cervical approach, two profited from an associated thoracic way. Only four patients did not have any complication of their cellulitis. One patient died. CONCLUSION: The early diagnosis of this pathology proves to be of primary importance. The treatment must be "aggressive". The drainage of mediastinitis proves to be sufficient by trans-cervical way in the event of the involvement of the higher part of the mediastinum (mediastinitis Endo type I) whereas a thoracotomy appears essential in the event of involvement beyond the carina (mediastinitis Endo type II).
Assuntos
Celulite (Flegmão)/complicações , Celulite (Flegmão)/terapia , Mediastinite/complicações , Mediastinite/terapia , Adulto , Idoso , Antibacterianos/uso terapêutico , Celulite (Flegmão)/microbiologia , Feminino , Humanos , Masculino , Mediastinite/microbiologia , Pessoa de Meia-Idade , Estudos Retrospectivos , ToracotomiaRESUMO
OBJECTIVES: This study was designed to evaluate the efficacy and morbidity of immediate tonsillectomy used to treat peritonsillar abscess (quinsy) and parapharyngeal abscess. SUBJECTS AND METHOD: This four-year, retrospective study was based on 31 patients hospitalised in a university hospital ENT and head and neck surgery department for peritonsillar and/or parapharyngeal abscess. All patients underwent immediate, bilateral tonsillectomy. The length of hospital stay, duration of antibiotic therapy, microbiological findings, complications, and the time to complete recovery and oropharyngeal healing were recorded. RESULTS: The patients' mean post-tonsillectomy hospital stay was 2.84 days (median: 3 days). No post-operative haemorrhage was observed. All patients were considered to be cured at the day 10 follow-up visit, and complete oropharyngeal healing was observed at the day 21 visit. The duration of antibiotic therapy ranged from 10 to 15 days (mean: 11.5 days; median: 10 days). DISCUSSION AND CONCLUSION: Immediate tonsillectomy appears to be a safe and effective surgical technique for the management of peritonsillar and parapharyngeal abscess; in particular, it markedly reduces patients' hospital stay (when performed early in the course of the disease) and duration of antibiotic therapy. Immediate tonsillectomy has become the first-line treatment for parapharyngeal abscess and several types of peritonsillar abscess in our department.
Assuntos
Abscesso/cirurgia , Abscesso Peritonsilar/cirurgia , Doenças Faríngeas/cirurgia , Tonsilectomia/métodos , Abscesso/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Combinação Amoxicilina e Clavulanato de Potássio/administração & dosagem , Antibacterianos/administração & dosagem , Anti-Inflamatórios/administração & dosagem , Criança , Feminino , Humanos , Tempo de Internação , Masculino , Metilprednisolona/administração & dosagem , Pessoa de Meia-Idade , Abscesso Peritonsilar/diagnóstico por imagem , Abscesso Peritonsilar/microbiologia , Doenças Faríngeas/diagnóstico por imagem , Doenças Faríngeas/microbiologia , Hemorragia Pós-Operatória/epidemiologia , Radiografia , Estudos Retrospectivos , Resultado do Tratamento , Cicatrização/fisiologia , Adulto JovemRESUMO
OBJECTIVES: The purpose of this study was to evaluate the advantages of surgery for diagnosis and treatment of cervical lymph node tuberculosis. MATERIAL AND METHODS: This was a retrospective study from 1st January 1998 to 31st December 2007 including 30 patients with cervical lymph node tuberculosis. The population included 60% autochthones with a mean age of 47.1 years and a female predominance (73.33%). RESULTS: The lymph nodes were most often supraclavicular, unilateral, firm, and a mean 3 cm at its largest span. Lymph nodes were excised for diagnosis in 22 patients, which demonstrated specific granulomatous and giant cell lesions with caseous necrosis in 21 patients out of 22. Five abscessed adenopathies required surgical drainage, and three cases required repeated lymph node cleaning after well-conducted medical treatment. CONCLUSION: Surgery retains an important place in the diagnosis and treatment of cervical lymph node tuberculosis.
Assuntos
Excisão de Linfonodo , Tomografia Computadorizada por Raios X , Tuberculose dos Linfonodos/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antituberculosos/efeitos adversos , Antituberculosos/uso terapêutico , Terapia Combinada , Estudos Transversais , Emigrantes e Imigrantes/estatística & dados numéricos , Feminino , França , Humanos , Linfonodos/diagnóstico por imagem , Linfonodos/patologia , Masculino , Pessoa de Meia-Idade , Pescoço/diagnóstico por imagem , Pescoço/cirurgia , Estudos Retrospectivos , Tuberculose dos Linfonodos/epidemiologia , Tuberculose dos Linfonodos/patologia , Tuberculose dos Linfonodos/cirurgia , Adulto JovemRESUMO
OBJECTIVES: To study and compare postoperative complications of total thyroidectomy for Graves disease and multinodular benign goiters. MATERIAL AND METHODS: A retrospective study on 176 patients (37 with Graves disease and 139 with multinodular benign goiters) over a period of 41 months was conducted. Postoperative calcemia and laryngeal palsy as well as hemorrhagic and infectious complications were studied and statistically compared using the Kruskal-Wallis test. RESULTS: There was no statistical difference concerning the occurrence of postoperative laryngeal palsy, hypoparathyroidism or hemorrhagic complications between these two groups of patients. Only a more frequent immediate postoperative hypocalcemia (day 1) in the Graves disease group was found. CONCLUSION: Total thyroidectomy in the surgical management of Graves disease, after a cautious medical preoperative preparation, appears to be a safe technique. Total thyroidectomy must be performed instead of subtotal thyroidectomy in order to avoid recurrences.
Assuntos
Bócio Nodular/cirurgia , Doença de Graves/cirurgia , Tireoidectomia/efeitos adversos , Adolescente , Adulto , Idoso de 80 Anos ou mais , Algoritmos , Feminino , Humanos , Hipocalcemia/etiologia , Hipoparatireoidismo/etiologia , Masculino , Pessoa de Meia-Idade , Hemorragia Pós-Operatória/etiologia , Estudos Retrospectivos , Tireoidectomia/métodos , Paralisia das Pregas Vocais/etiologiaRESUMO
Anatomical variants of the sinonasal cavities are common. About 15 major variants are described (nasal septal deviation is present in up to 62% of the population). Because the may lead to complications at the time of endovascular procedures or endoscopic sinonasal surgery (vascular, nervous, or osseous injury), there detection has medicolegal implications. Knowledge of anatomical variants by radiologists and ENT surgeons is thus required. We will describe these variants, their imaging features, frequency, implications and associated risk of potential complication.
Assuntos
Seios Paranasais/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Adulto , Artéria Carótida Interna/diagnóstico por imagem , Endoscopia , Seio Etmoidal/anatomia & histologia , Seio Etmoidal/diagnóstico por imagem , Seio Etmoidal/cirurgia , Humanos , Seio Maxilar/anatomia & histologia , Seio Maxilar/diagnóstico por imagem , Seio Maxilar/cirurgia , Septo Nasal/diagnóstico por imagem , Nervo Óptico/diagnóstico por imagem , Seios Paranasais/anatomia & histologia , Seios Paranasais/cirurgia , Fatores de Risco , Sinusite/diagnóstico por imagem , Seio Esfenoidal/anatomia & histologia , Seio Esfenoidal/diagnóstico por imagem , Seio Esfenoidal/cirurgiaRESUMO
OBJECTIVE: To highlight a poorly known anatomical variation of the lateral lobe of the thyroid gland, which can be useful in identifying the recurrent laryngeal nerve during thyroid surgery. MATERIALS AND METHODS: We performed a three-year prospective study of 79 thyroid surgery patients. Great attention was paid to anatomical variations of the thyroid gland (i.e. the presence or absence of a distinct tubercle of Zuckerkandl), the recurrent laryngeal nerve and the location of the parathyroid glands. RESULTS: A total of 71 right lobectomies and 74 left lobectomies were performed. Five tubercles of Zuckerkandl were identified (7.04 per cent of cases) and were useful in detecting the recurrent laryngeal nerve (but only on the right side). CONCLUSION: The tubercle of Zuckerkandl is a poorly known and variable anatomical feature of the thyroid gland which may not, in fact, be so rare. It arises for embryological reasons, and it can be a reliable anatomical landmark for identifying the recurrent laryngeal nerve during thyroid surgery. It should be included in the Nomina Anatomica as the 'processus posterior glandulae thyroideae' described by Zuckerkandl.
Assuntos
Nervo Laríngeo Recorrente/anatomia & histologia , Doenças da Glândula Tireoide/cirurgia , Glândula Tireoide/anatomia & histologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Nervo Laríngeo Recorrente/cirurgia , Traumatismos do Nervo Laríngeo Recorrente , Glândula Tireoide/inervação , Glândula Tireoide/cirurgia , Adulto JovemRESUMO
OBJECTIVES: To determine the value of technetium-99m bone scintigraphy in the screening of bone metastases in the systematic initial extension assessment of upper aerodigestive tract suamous cell carcinomas; to identify risk factors of these bone metastases for better screening. MATERIAL AND METHODS: In this prospective study, the initial assessment of tumoral extension was systematically associated with bone scintigraphy. Only patients with no malignant tumors were included in the study. Any skeletal fixation identified was then analyzed with standard radiography and/or tomodensitometry and with the patient's clinical progression to confirm whether or not the fixation was metastatic. The sensitivity and specificity of bone scintigraphy was then calculated. A correlation between bone pain or hypercalcemia and confirmed bone metastases was also systematically sought to determine whether these factors were predictive of bone metastases so as to better target the screening. RESULTS: Among the 55 patients included in the study, three had confirmed bone metastases. All were detected by the bone scintigraphy, with a sensitivity of 100%. However, the 20 false-positive results gave a low specificity of 62%. Bone pain was described by two patients, but they were among the three metastatic patients. Specificity was 100%, but the sensitivity was only 67%. Three patients had hypercalcemia: the three metastatic patients. The sensitivity and specificity were 100%. In the tumoral status of the three patients with bone metastasis, tumors were small, classified as T1 or T2, but with substantial node involvement, classified N3, and with invasion of the internal jugular vein in two cases. CONCLUSION: The incidence of bone metastases in the initial extension assessment was low; consequently, they are not sought systematically. However, their presence radically changes the prognosis and the therapeutic management, raising the question of screening. The technetium-99m bone scintigraphy has limits, with many false-positive resulting the need for additional investigations. Defining the risk factors for bone metastases would improve screening. Two questions remain: what factors are involved? The bone pain and the hypercalcemia must be analyzed with a larger number of cases, but they seem to be nonspecific. The node involvement stage could be a more reliable parameter, in particular in cases of jugular vein invasion; what method should be used? In the future, the PET scan could be the key procedure not only in the locoregional extension assessment, but also for general extensions, in a single procedure investigating the whole body.
Assuntos
Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/secundário , Carcinoma de Células Escamosas/diagnóstico por imagem , Carcinoma de Células Escamosas/secundário , Neoplasias de Cabeça e Pescoço/patologia , Adulto , Idoso , Carcinoma de Células Escamosas/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Estudos Prospectivos , CintilografiaRESUMO
To study the circumstances of diagnosis, predisposing factors, bacteriology and therapeutic management of parapharyngeal abscesses. This retrospective study over a period of 7 years concerned 16 patients hospitalized in an ENT and Head and Neck surgery department for parapharyngeal abscess. All patients were treated by intravenous antibiotics and steroids for 5-7 days. The length of hospital stay was 6-15 days. Parapharyngeal abscesses associated with peritonsillar and retropharyngeal abscess were all initially aspirated transorally for evacuation and bacteriologic examination. Five patients underwent surgical drainage (two via cervical incision, three by immediate tonsillectomy techniques and one by intra-oral drainage). Two patients presented jugular vein thrombosis. No life-threatening complication was observed. Patients were considered to be cured when cervical CT scan performed on D21-45 was normal. Parapharyngeal abscess is the second most common deep neck abscess after peritonsillar abscess. The diagnosis is both clinical and radiologic. CT scan is the best imaging examination for diagnosis and follow-up of parapharyngeal abscess. Non-complicated parapharyngeal abscesses require first-line medical management (intravenous antibiotics (amoxicillin and clavulanic acid) combined with steroids) and follow-up CT scan.
Assuntos
Antibacterianos/uso terapêutico , Drenagem/métodos , Glucocorticoides/uso terapêutico , Abscesso Peritonsilar/diagnóstico por imagem , Abscesso Peritonsilar/terapia , Adolescente , Adulto , Idoso , Antibacterianos/administração & dosagem , Criança , Diagnóstico Diferencial , Quimioterapia Combinada , Feminino , Seguimentos , Glucocorticoides/administração & dosagem , Humanos , Injeções Intravenosas , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
PURPOSE OF THE STUDY: We aimed to highlight a rare anatomical variation involving the recurrent laryngeal nerve, and to emphasise its implications for thyroid surgery. MATERIALS AND METHODS: Over a period of 13 years, 993 patients underwent thyroid surgery; 1557 recurrent laryngeal nerves (887 on the right side) were exposed. RESULTS: Three non-recurrent laryngeal nerves were found on the right side, associated with a retro-oesophageal subclavian artery. One case was suspected before surgery. DISCUSSION: Several variations in the path and branches of the recurrent laryngeal nerve have been reported in the literature. The frequency of occurrence of a non-recurrent laryngeal nerve is about 1 per cent, for patients undergoing thyroid surgery. Other surgically relevant anatomical variations of the recurrent laryngeal nerve include associations with the inferior thyroid artery and the presence of nerve branches. CONCLUSION: The recurrent laryngeal nerve must be carefully dissected and totally exposed during thyroid surgery in order to best preserve its function. Moreover, the thyroid surgeon must be aware of the existence of anatomical variations, which are not as rare as one may think.