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1.
AJR Am J Roentgenol ; 198(3): 708-16, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22358014

RESUMO

OBJECTIVE: The purpose of this study was to determine the effectiveness with which radiologists can use computer-aided detection (CADe) to detect cancer missed at screening. MATERIALS AND METHODS: An observer study was performed to measure the ability of radiologists to detect breast cancer on mammograms with and without CADe. The images in the study were from 300 analog mammographic examinations. In 234 cases the mammograms were read clinically as normal and free of cancer for at least 2 subsequent years. In the other 66 cases, cancers were missed clinically. In 256 cases, current and previous mammograms were available. Eight radiologists read the dataset and recorded a BI-RADS assessment, the location of the lesion, and their level of confidence that the patient should be recalled for diagnostic workup for each suspicious lesion. Jackknife alternative free-response receiver operating characteristic analysis was used. RESULTS: The jackknife alternative free-response receiver operating characteristic figure of merit was 0.641 without aid and 0.659 with aid (p = 0.06; 95% CI, -0.001 to 0.036). The sensitivity increased 9.9% (95% CI, 3.4-19%) and the callback rate 12.1% (95% CI, 7.3-20%) with CADe. Both increases were statistically significant (p < 0.001). Radiologists on average ignored 71% of correct computer prompts. CONCLUSION: Use of CADe can increase radiologist sensitivity 10% with a comparable increase in recall rate. There is potential for CADe to have a bigger clinical impact because radiologists failed to recognize a correct computer prompt in 71% of missed cancer cases [corrected].


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Diagnóstico por Computador , Erros de Diagnóstico/prevenção & controle , Mamografia , Feminino , Humanos , Curva ROC , Sensibilidade e Especificidade
2.
Surg Clin North Am ; 89(1): 235-47, x, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19186238

RESUMO

This article reviews the current state of diagnosis and treatment of soft tissue sarcomas. Etiology, staging, imaging, tissue sampling, and current treatment are all reviewed using updated references. Current standards for surgical treatment are emphasized and the future directions of treatment addressed.


Assuntos
Sarcoma/cirurgia , Diagnóstico por Imagem , Humanos , Neoplasias Pulmonares/secundário , Estadiamento de Neoplasias , Prognóstico , Radioterapia Adjuvante , Neoplasias Retroperitoneais/diagnóstico , Neoplasias Retroperitoneais/terapia , Sarcoma/tratamento farmacológico , Sarcoma/patologia , Sarcoma/radioterapia , Resultado do Tratamento
3.
J Diabetes Complications ; 23(2): 140-2, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-18358751

RESUMO

Diabetic muscle infarction, also known as diabetic myonecrosis, is an uncommon neuromuscular complication of longstanding diabetes. It usually involves the thigh or calf muscles. Patients typically present with severe pain in the affected area. This complication is more often seen in middle-aged diabetic patients with poorly controlled glycemia. We describe a 38-year-old female Type 1 diabetic patient who developed acute neck pain 3 weeks following islet transplantation.


Assuntos
Diabetes Mellitus Tipo 1/cirurgia , Transplante das Ilhotas Pancreáticas/efeitos adversos , Músculos do Pescoço/patologia , Cervicalgia/patologia , Necrose/patologia , Osteomielite/patologia , Complicações Pós-Operatórias/patologia , Adulto , Antibacterianos/uso terapêutico , Diabetes Mellitus Tipo 1/patologia , Doxiciclina/uso terapêutico , Feminino , Humanos , Nafcilina/uso terapêutico , Cervicalgia/tratamento farmacológico , Osteomielite/tratamento farmacológico , Complicações Pós-Operatórias/tratamento farmacológico
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