Factores asociados a infección de prótesis total de rodilla primaria en adultos mayores en un hospital de referencia en Perú. 2012-2015 / Factors associated with infection of primary total knee prosthesis in older adults in a referral hospital in Peru. 2012-2015

OBJETIVO: Determinar los factores de riesgo asociados a infección de prótesis de rodilla en pacientes adultos mayores en un hospital de referencia en Perú. Pacientes y metodología: Se realizó un estudio de casos y controles. La muestra calculada fue de 44 casos y 132 controles. Los datos fueron obtenidos retrospectivamente de las historias clínicas. Se realizaron pruebas U de Mann Whitney y chi cuadrado para comparación de casos y controles. Se calcularon las odds ratio (OR) en un análisis de regresión logística binaria para identificar factores de riesgo. Se consideró significativa una p < 0,05 y un intervalo de confianza (IC) del 95%. RESULTADOS: Los factores de riesgo significativos (p < 0,05) en el análisis bivariado fueron la obesidad (OR=9;72; IC95%: 4,47-21,14), el tabaquismo (OR=4,06; IC95%: 1,59-10,39), la artritis reumatoide (OR=4,66; IC95%: 1,52-14,32), la diabetes mellitus tipo2 (OR=5,63; IC95%: 2,69-11,78), el drenaje persistente (OR=9,27; IC95%: 3,85-22,31), la infección superficial (OR=6,87; IC95%: 3,25-14,49) y la estancia hospitalaria prolongada (OR=4,67; IC95%: 2,26-9,64). El análisis multivariado ajustado para las posibles variables de confusión determinó que los factores de riesgo significativos (p < 0,05) fueron la obesidad (ORa=9,14; IC95%: 3,28-25,48), la diabetes mellitus (ORa=3,77; IC95%: 1,38-10,32), el drenaje persistente (ORa=4,64; IC95%: 1,03-20,80) y la infección superficial de herida (ORa=27,35; IC95%: 2,57-290,64). CONCLUSIONES: Los factores de riesgo para infección de prótesis de rodilla identificados en este estudio son prevenibles. Los principales factores de riesgo para infección de prótesis de rodilla son la obesidad, la diabetes mellitus tipo 2, la infección superficial de herida operatoria y el drenaje persistente, los cuales, en conjunto o por separado, fueron considerados factores de riesgo en la población estudiada

OBJECTIVE: To determine the risk factors associated with prosthetic knee infection in elderly patients in a referral hospital in Peru. PATIENTS AND METHODS: A case and control study was performed. The calculated sample was 44 cases and 132 controls. The data were collected retrospectively from clinical records. U-Mann Whitney and Chi-square tests were performed in the comparison of cases and controls. Odds ratios (OR) were calculated in a binary logistic regression analysis to identify the risk factors, a P<.05 and a 95% confidence interval (CI) were considered significant. RESULTS: Significant (P<.05) risk factors evidenced in the bivariate analysis were obesity (OR=9.72; 95%CI: 4.47-21.14), smoking (OR=4.06; 95%CI: 1.59-10.39), rheumatoid arthritis (OR=4.66; 95%CI: 1.52-14.32), diabetes mellitus type2 (OR=5.63; 95%CI: 2.69-11.78), persistent drainage (OR=9.27; 95%CI: 3.85-22.31), superficial infection (OR=6.87; 95%CI: 3.25-14.49) and prolonged hospital stay (OR=4.67; 95%CI: 2.26-9.64). In the multivariate analysis where it was adjusted for confounding variables, it was determined that risk factors were obesity (ORa=9.14; 95%CI: 3.28-25.48), diabetes mellitus (ORa=3.77; 95%CI: 1.38-10.32), persistent drainage (ORa=4.64; 95%CI: 1.03-20.80) and superficial wound infection (ORa=27.35; 95%CI: 2.57-290.64). CONCLUSIONS: Risk factors for prosthetic knee infection identified in this study are preventable. The main risk factors were obesity, diabetes mellitus type 2, superficial wound infection and persistent drainage, which were considered together or separately to be risk factors in the population studied

Factors associated with infection of primary total knee prosthesis in older adults in a referral hospital in Peru. 2012-2015. / Factores asociados a infección de prótesis total de rodilla primaria en adultos mayores en un hospital de referencia en Perú. 2012-2015.

OBJECTIVE: To determine the risk factors associated with prosthetic knee infection in elderly patients in a referral hospital in Peru. PATIENTS AND METHODS: A case and control study was performed. The calculated sample was 44 cases and 132 controls. The data were collected retrospectively from clinical records. U-Mann Whitney and Chi-square tests were performed in the comparison of cases and controls. Odds ratios (OR) were calculated in a binary logistic regression analysis to identify the risk factors, a P<.05 and a 95% confidence interval (CI) were considered significant. RESULTS: Significant (P<.05) risk factors evidenced in the bivariate analysis were obesity (OR=9.72; 95%CI: 4.47-21.14), smoking (OR=4.06; 95%CI: 1.59-10.39), rheumatoid arthritis (OR=4.66; 95%CI: 1.52-14.32), diabetes mellitus type2 (OR=5.63; 95%CI: 2.69-11.78), persistent drainage (OR=9.27; 95%CI: 3.85-22.31), superficial infection (OR=6.87; 95%CI: 3.25-14.49) and prolonged hospital stay (OR=4.67; 95%CI: 2.26-9.64). In the multivariate analysis where it was adjusted for confounding variables, it was determined that risk factors were obesity (ORa=9.14; 95%CI: 3.28-25.48), diabetes mellitus (ORa=3.77; 95%CI: 1.38-10.32), persistent drainage (ORa=4.64; 95%CI: 1.03-20.80) and superficial wound infection (ORa=27.35; 95%CI: 2.57-290.64). CONCLUSIONS: Risk factors for prosthetic knee infection identified in this study are preventable. The main risk factors were obesity, diabetes mellitus type2, superficial wound infection and persistent drainage, which were considered together or separately to be risk factors in the population studied.